130 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8HMD0	Uncharacterized protein. (720 aa)
	A0A1L8EL97	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (315 aa)
	Map2.S	Microtubule-associated protein. (1811 aa)
	Kremen2.S	Uncharacterized protein. (421 aa)
	A0A1L8ESG7	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	A0A1L8EVC1	Sema domain-containing protein. (1089 aa)
	Map2.L	Microtubule-associated protein. (1769 aa)
	kremen2	Uncharacterized protein. (420 aa)
	A0A1L8EZY9	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
	bag5	Uncharacterized protein. (452 aa)
	tsc1	Uncharacterized protein. (1104 aa)
	sema6c	Sema domain-containing protein; Belongs to the semaphorin family. (1042 aa)
	sema4a	Sema domain-containing protein; Belongs to the semaphorin family. (742 aa)
	efna1	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (216 aa)
	tsc1-2	Uncharacterized protein. (1102 aa)
	bag5-2	Uncharacterized protein. (453 aa)
	psen1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
	sema6c-2	Sema domain-containing protein; Belongs to the semaphorin family. (995 aa)
	Sema4a.L	Sema domain-containing protein; Belongs to the semaphorin family. (719 aa)
	A0A1L8FDF6	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (301 aa)
	Sema4g.S	Uncharacterized protein; Belongs to the semaphorin family. (797 aa)
	Slit1.S	Uncharacterized protein. (1529 aa)
	A0A1L8FFM1	Uncharacterized protein. (588 aa)
	A0A1L8FHW0	Uncharacterized protein. (480 aa)
	inpp5f	Uncharacterized protein. (1108 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	znf365-2	Uncharacterized protein. (396 aa)
	sema4g	Uncharacterized protein; Belongs to the semaphorin family. (831 aa)
	A0A1L8FJF5	Uncharacterized protein. (1320 aa)
	A0A1L8FKX2	Uncharacterized protein. (305 aa)
	thy1	Ig-like domain-containing protein. (165 aa)
	Mag.L	Uncharacterized protein. (625 aa)
	A0A1L8FQD6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Mylip.L	Uncharacterized protein. (445 aa)
	Dtnbp1.L	Uncharacterized protein. (317 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	A0A1L8G0P6	Uncharacterized protein. (797 aa)
	ngef	Uncharacterized protein. (691 aa)
	Neu4.S	Sialidase domain-containing protein. (495 aa)
	A0A1L8G548	Uncharacterized protein. (465 aa)
	Bcl11a.L	Uncharacterized protein. (710 aa)
	ngef-2	Uncharacterized protein. (691 aa)
	ryk	Uncharacterized protein. (596 aa)
	Neu4.L	Sialidase domain-containing protein. (482 aa)
	A0A1L8GG21	Uncharacterized protein. (1334 aa)
	ifrd2	Uncharacterized protein. (435 aa)
	sema3b	Uncharacterized protein; Belongs to the semaphorin family. (773 aa)
	sema3f	Uncharacterized protein; Belongs to the semaphorin family. (780 aa)
	A0A1L8GML0	Uncharacterized protein. (1260 aa)
	sema3f-2	Uncharacterized protein; Belongs to the semaphorin family. (780 aa)
	sema3b-2	Uncharacterized protein; Belongs to the semaphorin family. (773 aa)
	Fkbp4.S	Peptidylprolyl isomerase. (447 aa)
	sema4c	Uncharacterized protein; Belongs to the semaphorin family. (833 aa)
	minar1	UPF0258 domain-containing protein. (857 aa)
	Sema4b.S	Sema domain-containing protein; Belongs to the semaphorin family. (835 aa)
	Sema6d.S	Sema domain-containing protein; Belongs to the semaphorin family. (1047 aa)
	sema3a	Uncharacterized protein; Belongs to the semaphorin family. (771 aa)
	Sema3c.S	Uncharacterized protein; Belongs to the semaphorin family. (748 aa)
	sema3d	Uncharacterized protein; Belongs to the semaphorin family. (766 aa)
	sema3e	Sema domain-containing protein; Belongs to the semaphorin family. (769 aa)
	A0A1L8GUT1	dNK domain-containing protein. (331 aa)
	ifrd1	Uncharacterized protein. (426 aa)
	lrrk2	Uncharacterized protein. (2514 aa)
	sema3e-2	Sema domain-containing protein; Belongs to the semaphorin family. (276 aa)
	sema3c	Uncharacterized protein; Belongs to the semaphorin family. (748 aa)
	sema3d-2	Uncharacterized protein; Belongs to the semaphorin family. (776 aa)
	sema3a-2	Uncharacterized protein; Belongs to the semaphorin family. (774 aa)
	A0A1L8GZY9	Sema domain-containing protein; Belongs to the semaphorin family. (574 aa)
	sema4b	Uncharacterized protein; Belongs to the semaphorin family. (835 aa)
	minar1-2	UPF0258 domain-containing protein. (848 aa)
	sema4c-2	Uncharacterized protein; Belongs to the semaphorin family. (834 aa)
	A0A1L8H4S2	LRRCT domain-containing protein. (455 aa)
	A0A1L8H818	Protein kinase domain-containing protein. (1055 aa)
	A0A1L8H819	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (325 aa)
	Efnb2.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (329 aa)
	A0A1L8HA48	DMAP-interaction domain-containing protein. (1538 aa)
	Fat3.S	Uncharacterized protein. (3417 aa)
	A0A1L8HAZ0	Uncharacterized protein. (1286 aa)
	Rtn4rl1.L	LRRCT domain-containing protein. (461 aa)
	lrig2	Uncharacterized protein. (1075 aa)
	ulk2	Protein kinase domain-containing protein. (1073 aa)
	ube3a	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (908 aa)
	A0A1L8HI96	DMAP-interaction domain-containing protein. (1579 aa)
	spart	MIT domain-containing protein. (595 aa)
	A0A1L8HKV2	Amidohydro-rel domain-containing protein. (682 aa)
	Slit2.S	Uncharacterized protein. (1530 aa)
	A0A1L8HLT5	AIF-MLS domain-containing protein. (377 aa)
	Prag1.S	Protein kinase domain-containing protein. (1282 aa)
	A0A1L8HMZ5	Sema domain-containing protein; Belongs to the semaphorin family. (917 aa)
	gak	Uncharacterized protein. (1316 aa)
	lpar1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	A0A1L8HPH6	Uncharacterized protein; Belongs to the semaphorin family. (853 aa)
	A0A1L8HPX7	IPPc domain-containing protein. (772 aa)
	Rtn4r.S	Uncharacterized protein. (494 aa)
	Ulk1.S	Protein kinase domain-containing protein. (967 aa)
	Kremen1.S	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (452 aa)
	sema6a	Sema domain-containing protein; Belongs to the semaphorin family. (1018 aa)
	A0A1L8HRQ5	PID domain-containing protein. (784 aa)
	Crmp1.L	Amidohydro-rel domain-containing protein. (682 aa)
	A0A1L8HTQ2	Uncharacterized protein. (1521 aa)
	mgarp	AIF-MLS domain-containing protein. (550 aa)
	rufy3	Uncharacterized protein. (732 aa)
	A0A1L8HW98	Sema domain-containing protein; Belongs to the semaphorin family. (917 aa)
	paqr3	Uncharacterized protein. (311 aa)
	A0A1L8HYI9	Uncharacterized protein; Belongs to the semaphorin family. (855 aa)
	A0A1L8HYR3	CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (497 aa)
	Rtn4r.L	Uncharacterized protein. (494 aa)
	inpp5j	IPPc domain-containing protein. (784 aa)
	ulk1	Protein kinase domain-containing protein. (1049 aa)
	kremen1	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
	sema6a-2	Sema domain-containing protein; Belongs to the semaphorin family. (1018 aa)
	A0A1L8I2I6	PID domain-containing protein. (751 aa)
	A0A310U3N1	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (445 aa)
	lpar1-2	Lysophosphatidic acid G-protein-coupled receptor 2; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	sema6d	Semaphorin 6D4; Belongs to the semaphorin family. (1085 aa)
	cib1	LOC496348 protein. (190 aa)
	snapin	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (122 aa)
	cib1-2	LOC495358 protein. (190 aa)
	ifrd2-2	Ifrd2 protein. (434 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	rab29	MGC80435 protein. (204 aa)
	dguok	MGC82558 protein. (265 aa)
	paqr3-2	MGC83905 protein. (309 aa)
	fkbp4	Peptidylprolyl isomerase. (447 aa)
	sema5b	MGC68835 protein. (1088 aa)
	ifrd1-2	MGC69123 protein. (425 aa)
	efnb2	Efnb2a protein; Belongs to the ephrin family. (329 aa)
	ube3a-2	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (908 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EL97	A0A1L8G548	A0A1L8EL97	A0A1L8G548	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.602
A0A1L8EL97	ryk	A0A1L8EL97	A0A1L8GB75	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.602
A0A1L8ESG7	A0A1L8G548	A0A1L8ESG7	A0A1L8G548	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.602
A0A1L8ESG7	ryk	A0A1L8ESG7	A0A1L8GB75	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.602
A0A1L8EZY9	Map2.L	A0A1L8EZY9	A0A1L8EWQ3	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Microtubule-associated protein.	0.400
A0A1L8EZY9	psen1	A0A1L8EZY9	A0A1L8FAH5	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.900
A0A1L8EZY9	thy1	A0A1L8EZY9	A0A1L8FLF5	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Ig-like domain-containing protein.	0.624
A0A1L8FDF6	Efnb2.S	A0A1L8FDF6	A0A1L8H932	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	0.468
A0A1L8FDF6	efnb2	A0A1L8FDF6	Q6PF53	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Efnb2a protein; Belongs to the ephrin family.	0.468
A0A1L8FHW0	Rtn4r.L	A0A1L8FHW0	A0A1L8I065	Uncharacterized protein.	Uncharacterized protein.	0.607
A0A1L8FHW0	Rtn4r.S	A0A1L8FHW0	A0A1L8HQ46	Uncharacterized protein.	Uncharacterized protein.	0.607
A0A1L8FJF5	sema3a	A0A1L8FJF5	A0A1L8GTU0	Uncharacterized protein.	Uncharacterized protein; Belongs to the semaphorin family.	0.575
A0A1L8FJF5	sema3a-2	A0A1L8FJF5	A0A1L8GZD9	Uncharacterized protein.	Uncharacterized protein; Belongs to the semaphorin family.	0.575
A0A1L8FJF5	sema3f	A0A1L8FJF5	A0A1L8GHF1	Uncharacterized protein.	Uncharacterized protein; Belongs to the semaphorin family.	0.512
A0A1L8FJF5	sema3f-2	A0A1L8FJF5	A0A1L8GP74	Uncharacterized protein.	Uncharacterized protein; Belongs to the semaphorin family.	0.512
A0A1L8FQD6	A0A1L8G548	A0A1L8FQD6	A0A1L8G548	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.602
A0A1L8FQD6	ryk	A0A1L8FQD6	A0A1L8GB75	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.602
A0A1L8G548	A0A1L8EL97	A0A1L8G548	A0A1L8EL97	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.602
A0A1L8G548	A0A1L8ESG7	A0A1L8G548	A0A1L8ESG7	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.602
A0A1L8G548	A0A1L8FQD6	A0A1L8G548	A0A1L8FQD6	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.602