STRINGSTRING
Sema6d.S Sema6d.S Sema4b.S Sema4b.S sema4c sema4c pwwp2a pwwp2a anxa6 anxa6 A0A1L8GQT6 A0A1L8GQT6 kbtbd8-2 kbtbd8-2 sema3b-2 sema3b-2 A0A1L8EP11 A0A1L8EP11 gbx2.2 gbx2.2 Fn1.S Fn1.S nrp2 nrp2 sox8 sox8 A0A1L8EVC1 A0A1L8EVC1 Acvr1.L Acvr1.L Gbx2.2.L Gbx2.2.L A0A1L8FJZ9 A0A1L8FJZ9 Ret.L Ret.L A0A1L8FQN3 A0A1L8FQN3 foxc1 foxc1 Rdh10.S Rdh10.S nrp1 nrp1 foxc1-2 foxc1-2 jag1 jag1 A0A1L8G3R8 A0A1L8G3R8 Jag1.L Jag1.L gbx2.1-2 gbx2.1-2 ednra-2 ednra-2 sema5b sema5b alcam alcam sema6d sema6d pdcd6 pdcd6 edn1 edn1 sox9-a sox9-a fbxl17 fbxl17 gbx2.1 gbx2.1 ednra ednra A0A310TSJ1 A0A310TSJ1 A0A310TLP0 A0A310TLP0 A0A1L8I2V3 A0A1L8I2V3 Gdnf.L Gdnf.L A0A1L8I2G3 A0A1L8I2G3 sema6a-2 sema6a-2 A0A1L8HYI9 A0A1L8HYI9 A0A1L8HWX7 A0A1L8HWX7 A0A1L8HW98 A0A1L8HW98 hand2 hand2 Phox2b Phox2b tapt1 tapt1 A0A1L8HRY9 A0A1L8HRY9 Gdnf.S Gdnf.S sema6a sema6a A0A1L8HPH6 A0A1L8HPH6 A0A1L8HND0 A0A1L8HND0 A0A1L8HMZ5 A0A1L8HMZ5 A0A1L8HLI5 A0A1L8HLI5 Phox2b.S Phox2b.S Tapt1.S Tapt1.S ednrb-2 ednrb-2 Alcam.L Alcam.L pef1-2 pef1-2 klhl12-2 klhl12-2 phactr4-2 phactr4-2 ednrb ednrb pef1 pef1 phactr4 phactr4 klhl12 klhl12 sema4c-2 sema4c-2 sema4b sema4b A0A1L8GZY9 A0A1L8GZY9 Smo.L Smo.L sema3a-2 sema3a-2 sema3d-2 sema3d-2 sema3c sema3c sema3e-2 sema3e-2 Anxa6.L Anxa6.L sema3e sema3e sema3d sema3d Sema3c.S Sema3c.S sema3a sema3a Smo.S Smo.S sema4a sema4a A0A1L8F5F3 A0A1L8F5F3 ednrb2 ednrb2 gsc gsc fgf19 fgf19 Foxc2.S Foxc2.S sox10 sox10 sema3b sema3b sema3f sema3f kbtbd8 kbtbd8 fgf19-2 fgf19-2 foxc2 foxc2 sox10-2 sox10-2 sema3f-2 sema3f-2 A0A1L8EWN9 A0A1L8EWN9 nrp2-2 nrp2-2 Sox8.L Sox8.L A0A1L8EZF8 A0A1L8EZF8 Gsc.S Gsc.S sema6c-2 sema6c-2 Ednrb2.S Ednrb2.S sema6c sema6c Sema4a.L Sema4a.L A0A1L8FDB0 A0A1L8FDB0 cyp26c1 cyp26c1 Sema4g.S Sema4g.S cyp26c1-2 cyp26c1-2 sema4g sema4g
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sema6d.SSema domain-containing protein; Belongs to the semaphorin family. (1047 aa)
Sema4b.SSema domain-containing protein; Belongs to the semaphorin family. (835 aa)
sema4cUncharacterized protein; Belongs to the semaphorin family. (833 aa)
pwwp2aPWWP domain-containing protein 2A; H2A.Z-specific chromatin binding protein which plays an important role in the neural crest cell differentiation and/or migration during early development and is essential for the development of the head and eye. (784 aa)
anxa6Annexin. (674 aa)
A0A1L8GQT6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
kbtbd8-2BTB domain-containing protein. (600 aa)
sema3b-2Uncharacterized protein; Belongs to the semaphorin family. (773 aa)
A0A1L8EP11Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (484 aa)
gbx2.2Homeobox domain-containing protein. (340 aa)
Fn1.SUncharacterized protein. (2480 aa)
nrp2Neuropilin; Belongs to the neuropilin family. (933 aa)
sox8HMG box domain-containing protein. (461 aa)
A0A1L8EVC1Sema domain-containing protein. (1089 aa)
Acvr1.LReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (624 aa)
Gbx2.2.LHomeobox domain-containing protein. (340 aa)
A0A1L8FJZ9LisH domain-containing protein. (1036 aa)
Ret.LProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1096 aa)
A0A1L8FQN3Neuropilin; Belongs to the neuropilin family. (883 aa)
foxc1Fork-head domain-containing protein. (492 aa)
Rdh10.SUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (926 aa)
foxc1-2Fork-head domain-containing protein. (495 aa)
jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1206 aa)
A0A1L8G3R8G_PROTEIN_RECEP_F1_2 domain-containing protein. (459 aa)
Jag1.LDelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
gbx2.1-2Homeobox protein GBX-2b. (336 aa)
ednra-2Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (415 aa)
sema5bMGC68835 protein. (1088 aa)
alcamMGC84135 protein. (570 aa)
sema6dSemaphorin 6D4; Belongs to the semaphorin family. (1085 aa)
pdcd6Pdcd6 protein. (187 aa)
edn1LOC100158354 protein. (221 aa)
sox9-aSex determining region Y-box 9. (477 aa)
fbxl17F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerization of BTB domain-containing proteins (dimerization quality control, DQC). FBXL17 specifically recognizes and binds a conserved degron of non-consecutive residues present at the interface of BTB dimers of aberrant composition: aberrant BTB dimer are then ubiquitinated by the SCF(FBXL17) complex and degraded by the proteaseome (By similarity). The ability of the SCF(FBXL17) complex to eliminate co [...] (673 aa)
gbx2.1Homeobox domain-containing protein. (340 aa)
ednraLOC100036912 protein; Belongs to the G-protein coupled receptor 1 family. (415 aa)
A0A310TSJ1CUB domain-containing protein. (99 aa)
A0A310TLP0G_PROTEIN_RECEP_F1_2 domain-containing protein. (293 aa)
A0A1L8I2V3Mothers against decapentaplegic homolog. (510 aa)
Gdnf.LTGF_BETA_2 domain-containing protein. (332 aa)
A0A1L8I2G3Arb2 domain-containing protein. (422 aa)
sema6a-2Sema domain-containing protein; Belongs to the semaphorin family. (1018 aa)
A0A1L8HYI9Uncharacterized protein; Belongs to the semaphorin family. (855 aa)
A0A1L8HWX7TGF_BETA_2 domain-containing protein. (211 aa)
A0A1L8HW98Sema domain-containing protein; Belongs to the semaphorin family. (917 aa)
hand2BHLH domain-containing protein. (210 aa)
Phox2bHomeobox domain-containing protein. (293 aa)
tapt1Uncharacterized protein. (545 aa)
A0A1L8HRY9Mothers against decapentaplegic homolog. (549 aa)
Gdnf.SGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (227 aa)
sema6aSema domain-containing protein; Belongs to the semaphorin family. (1018 aa)
A0A1L8HPH6Uncharacterized protein; Belongs to the semaphorin family. (853 aa)
A0A1L8HND0TGF_BETA_2 domain-containing protein. (221 aa)
A0A1L8HMZ5Sema domain-containing protein; Belongs to the semaphorin family. (917 aa)
A0A1L8HLI5BHLH domain-containing protein. (272 aa)
Phox2b.SHomeobox domain-containing protein. (293 aa)
Tapt1.SUncharacterized protein. (546 aa)
ednrb-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (431 aa)
Alcam.LUncharacterized protein. (573 aa)
pef1-2Uncharacterized protein. (283 aa)
klhl12-2BTB domain-containing protein. (564 aa)
phactr4-2Phosphatase and actin regulator. (709 aa)
ednrbG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (431 aa)
pef1Uncharacterized protein. (278 aa)
phactr4Phosphatase and actin regulator. (694 aa)
klhl12BTB domain-containing protein. (564 aa)
sema4c-2Uncharacterized protein; Belongs to the semaphorin family. (834 aa)
sema4bUncharacterized protein; Belongs to the semaphorin family. (835 aa)
A0A1L8GZY9Sema domain-containing protein; Belongs to the semaphorin family. (574 aa)
Smo.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
sema3a-2Uncharacterized protein; Belongs to the semaphorin family. (774 aa)
sema3d-2Uncharacterized protein; Belongs to the semaphorin family. (776 aa)
sema3cUncharacterized protein; Belongs to the semaphorin family. (748 aa)
sema3e-2Sema domain-containing protein; Belongs to the semaphorin family. (276 aa)
Anxa6.LAnnexin. (673 aa)
sema3eSema domain-containing protein; Belongs to the semaphorin family. (769 aa)
sema3dUncharacterized protein; Belongs to the semaphorin family. (766 aa)
Sema3c.SUncharacterized protein; Belongs to the semaphorin family. (748 aa)
sema3aUncharacterized protein; Belongs to the semaphorin family. (771 aa)
Smo.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
sema4aSema domain-containing protein; Belongs to the semaphorin family. (742 aa)
A0A1L8F5F3OTU domain-containing protein. (493 aa)
ednrb2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (433 aa)
gscHomeobox domain-containing protein. (294 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
Foxc2.SFork-head domain-containing protein. (461 aa)
sox10HMG box domain-containing protein. (438 aa)
sema3bUncharacterized protein; Belongs to the semaphorin family. (773 aa)
sema3fUncharacterized protein; Belongs to the semaphorin family. (780 aa)
kbtbd8BTB domain-containing protein. (600 aa)
fgf19-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
foxc2Fork-head domain-containing protein. (465 aa)
sox10-2HMG box domain-containing protein. (446 aa)
sema3f-2Uncharacterized protein; Belongs to the semaphorin family. (780 aa)
A0A1L8EWN9Uncharacterized protein. (2484 aa)
nrp2-2Neuropilin; Belongs to the neuropilin family. (934 aa)
Sox8.LHMG box domain-containing protein. (459 aa)
A0A1L8EZF8OTU domain-containing protein. (415 aa)
Gsc.SHomeobox domain-containing protein. (243 aa)
sema6c-2Sema domain-containing protein; Belongs to the semaphorin family. (995 aa)
Ednrb2.SG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (435 aa)
sema6cSema domain-containing protein; Belongs to the semaphorin family. (1042 aa)
Sema4a.LSema domain-containing protein; Belongs to the semaphorin family. (719 aa)
A0A1L8FDB0Mothers against decapentaplegic homolog. (514 aa)
cyp26c1Uncharacterized protein; Belongs to the cytochrome P450 family. (602 aa)
Sema4g.SUncharacterized protein; Belongs to the semaphorin family. (797 aa)
cyp26c1-2Uncharacterized protein; Belongs to the cytochrome P450 family. (605 aa)
sema4gUncharacterized protein; Belongs to the semaphorin family. (831 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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