58 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8ETM3	Uncharacterized protein. (500 aa)
	bsg-2	LOC100037021 protein. (387 aa)
	A0A1L8HYC9	Annexin. (242 aa)
	A0A1L8HY95	Annexin. (338 aa)
	nsg1-2	Uncharacterized protein. (185 aa)
	anxa1.2	Annexin. (338 aa)
	bsg	Uncharacterized protein. (387 aa)
	nsg1	Uncharacterized protein. (185 aa)
	Myo1c.L	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1044 aa)
	Cldn4.L	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	vangl1-2	Vang-like protein. (499 aa)
	Myo1c.S	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1028 aa)
	vangl1	Vang-like protein. (503 aa)
	slc26a5-2	STAS domain-containing protein. (752 aa)
	A0A1L8GW83	Uncharacterized protein; Belongs to the potassium channel family. (604 aa)
	ptpro	Uncharacterized protein. (1289 aa)
	slc26a5	STAS domain-containing protein. (754 aa)
	A0A1L8GQW8	Uncharacterized protein; Belongs to the potassium channel family. (667 aa)
	A0A1L8GM23	Uncharacterized protein. (1150 aa)
	kcnq1	Uncharacterized protein; Belongs to the potassium channel family. (652 aa)
	A0A1L8GFI0	Uncharacterized protein. (848 aa)
	A0A1L8GD44	Uncharacterized protein; Belongs to the potassium channel family. (637 aa)
	cldn1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	bves-2	Uncharacterized protein. (349 aa)
	A0A1L8G8C8	AKAP7_RIRII_bdg domain-containing protein. (79 aa)
	A0A1L8G867	Uncharacterized protein. (500 aa)
	Epcam.L	Thyroglobulin type-1 domain-containing protein. (314 aa)
	fzd3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	bves	Uncharacterized protein. (347 aa)
	Epcam.S	Thyroglobulin type-1 domain-containing protein. (314 aa)
	A0A1L8FLE6	C1q domain-containing protein. (221 aa)
	vangl2-2	Vang-like protein. (521 aa)
	vangl2	Vang-like protein. (521 aa)
	A0A1L8F2E9	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (201 aa)
	pkd1	Uncharacterized protein. (4353 aa)
	tbcd	TFCD_C domain-containing protein. (1187 aa)
	A0A1L8EUA7	PKD domain-containing protein. (501 aa)
	A0A1L8EUA6	Uncharacterized protein. (3827 aa)
	fz3	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	A0A1L8ETL8	MFS domain-containing protein. (502 aa)
	A0A1L8ETL2	MFS domain-containing protein. (491 aa)
	A0A1L8ETK5	Uncharacterized protein. (531 aa)
	A0A1L8ESJ4	BTB domain-containing protein; Belongs to the potassium channel family. (874 aa)
	A0A1L8EN81	TFCD_C domain-containing protein. (997 aa)
	Kcnb1.L	BTB domain-containing protein; Belongs to the potassium channel family. (876 aa)
	cldn1-2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	ctnnb1-2	Ctnnb1-prov protein. (781 aa)
	anxa1.1-2	Annexin. (343 aa)
	cldn5-2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)
	MGC82764	MGC82764 protein. (245 aa)
	cldn5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)
	slc16a3	MGC81989 protein. (472 aa)
	anxa1.1	Annexin. (343 aa)
	anxa1.3	Annexin. (363 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	cldn12	LOC496360 protein. (245 aa)
	arl2	LOC496366 protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	gjb1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (265 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EN81	arl2	A0A1L8EN81	Q5HZL3	TFCD_C domain-containing protein.	LOC496366 protein; Belongs to the small GTPase superfamily. Arf family.	0.968
A0A1L8EUA6	ctnnb1	A0A1L8EUA6	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.417
A0A1L8F2E9	ctnnb1	A0A1L8F2E9	Q63ZT4	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Beta-catenin protein.	0.425
A0A1L8F2E9	ctnnb1-2	A0A1L8F2E9	Q7ZX35	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Ctnnb1-prov protein.	0.425
A0A1L8GD44	A0A1L8GQW8	A0A1L8GD44	A0A1L8GQW8	Uncharacterized protein; Belongs to the potassium channel family.	Uncharacterized protein; Belongs to the potassium channel family.	0.902
A0A1L8GD44	kcnq1	A0A1L8GD44	A0A1L8GJB4	Uncharacterized protein; Belongs to the potassium channel family.	Uncharacterized protein; Belongs to the potassium channel family.	0.900
A0A1L8GQW8	A0A1L8GD44	A0A1L8GQW8	A0A1L8GD44	Uncharacterized protein; Belongs to the potassium channel family.	Uncharacterized protein; Belongs to the potassium channel family.	0.902
A0A1L8GQW8	kcnq1	A0A1L8GQW8	A0A1L8GJB4	Uncharacterized protein; Belongs to the potassium channel family.	Uncharacterized protein; Belongs to the potassium channel family.	0.902
Cldn4.L	Epcam.L	A0A1L8HDJ7	A0A1L8G611	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Thyroglobulin type-1 domain-containing protein.	0.428
Cldn4.L	Epcam.S	A0A1L8HDJ7	A0A1L8G1E7	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Thyroglobulin type-1 domain-containing protein.	0.526
Cldn4.L	MGC82764	A0A1L8HDJ7	Q6GPN3	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	MGC82764 protein.	0.577
Cldn4.L	cldn1	A0A1L8HDJ7	A0A1L8GA96	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.808
Cldn4.L	cldn1-2	A0A1L8HDJ7	Q8AVG4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.809
Cldn4.L	cldn12	A0A1L8HDJ7	Q5HZM0	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	LOC496360 protein.	0.577
Cldn4.L	cldn5	A0A1L8HDJ7	Q6GNW1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.799
Cldn4.L	cldn5-2	A0A1L8HDJ7	Q6PA22	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.798
Epcam.L	Cldn4.L	A0A1L8G611	A0A1L8HDJ7	Thyroglobulin type-1 domain-containing protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.428
Epcam.L	cldn1	A0A1L8G611	A0A1L8GA96	Thyroglobulin type-1 domain-containing protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.410
Epcam.L	cldn1-2	A0A1L8G611	Q8AVG4	Thyroglobulin type-1 domain-containing protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.410
Epcam.L	ctnnb1	A0A1L8G611	Q63ZT4	Thyroglobulin type-1 domain-containing protein.	Beta-catenin protein.	0.428