58 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8G548	Uncharacterized protein. (465 aa)
	A0A1L8GFH0	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (946 aa)
	A0A1L8GFZ8	Uncharacterized protein. (519 aa)
	A0A1L8GHR8	Uncharacterized protein. (300 aa)
	fjx1-2	Uncharacterized protein. (386 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	Wls.L	Uncharacterized protein. (541 aa)
	A0A1L8GM33	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (944 aa)
	A0A1L8GMD0	Uncharacterized protein. (586 aa)
	A0A1L8GQT6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	sfrp1	Uncharacterized protein. (311 aa)
	ptpro	Uncharacterized protein. (1289 aa)
	Sfrp1.L	Uncharacterized protein. (311 aa)
	fzd9	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	A0A1L8HD44	FZ domain-containing protein. (183 aa)
	fzd9-2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
	A0A1L8HJF4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (456 aa)
	ror2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	fzd10	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
	sfrp2	Uncharacterized protein. (295 aa)
	A0A1L8HXI8	Uncharacterized protein. (510 aa)
	fzd10a	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
	fz3	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	Xporc-d	Xporc-d protein; Belongs to the membrane-bound acyltransferase family. (450 aa)
	sfrp2-2	Sfrp2-prov protein. (298 aa)
	ror2-2	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	sfrp5	Secreted frizzled-related protein 5. (315 aa)
	frzb2	Putative wnt inhibitor frzb2. (295 aa)
	szl	Putative wnt inhibitor frzb3. (280 aa)
	wls	Uncharacterized protein. (541 aa)
	fjx1	Uncharacterized protein. (385 aa)
	ryk	Uncharacterized protein. (596 aa)
	fzd3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	fzd6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
	cthrc1-2	Uncharacterized protein. (235 aa)
	apcdd1	Uncharacterized protein. (515 aa)
	A0A1L8FX32	Uncharacterized protein. (971 aa)
	sfrp4	Uncharacterized protein. (353 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	cthrc1	Uncharacterized protein. (235 aa)
	Fzd6.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
	A0A1L8FSN6	Uncharacterized protein. (800 aa)
	A0A1L8FQX7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
	Sfrp5.S	Uncharacterized protein. (315 aa)
	A0A1L8EX74	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	Frzb-1	Uncharacterized protein. (319 aa)
	A0A1L8ET08	APCDDC domain-containing protein. (373 aa)
	A0A1L8ES96	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (554 aa)
	A0A1L8EPZ4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	Frzb.S	Uncharacterized protein. (319 aa)
	apcdd1l	Uncharacterized protein. (499 aa)
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	A0A1L8EKF4	FZ domain-containing protein. (134 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EPZ4	A0A1L8GFH0	A0A1L8EPZ4	A0A1L8GFH0	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.792
A0A1L8EPZ4	A0A1L8GM33	A0A1L8EPZ4	A0A1L8GM33	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.792
A0A1L8EPZ4	A0A1L8GQT6	A0A1L8EPZ4	A0A1L8GQT6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.889
A0A1L8EPZ4	Fzd6.S	A0A1L8EPZ4	A0A1L8FTP5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.402
A0A1L8EPZ4	Lrp5.L	A0A1L8EPZ4	A0A1L8GJX4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.887
A0A1L8EPZ4	Sfrp1.L	A0A1L8EPZ4	A0A1L8H1S5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.658
A0A1L8EPZ4	Sfrp5.S	A0A1L8EPZ4	A0A1L8FEX3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.658
A0A1L8EPZ4	fzd6	A0A1L8EPZ4	A0A1L8FZR1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.402
A0A1L8EPZ4	ror2	A0A1L8EPZ4	A0A1L8HPI6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.792
A0A1L8EPZ4	ror2-2	A0A1L8EPZ4	Q8AV69	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.792
A0A1L8EPZ4	ryk	A0A1L8EPZ4	A0A1L8GB75	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.702
A0A1L8EPZ4	sfrp1	A0A1L8EPZ4	A0A1L8GRT5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.658
A0A1L8EPZ4	sfrp2	A0A1L8EPZ4	A0A1L8HUI3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.675
A0A1L8EPZ4	sfrp2-2	A0A1L8EPZ4	Q7ZXM6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Sfrp2-prov protein.	0.675
A0A1L8EPZ4	sfrp4	A0A1L8EPZ4	A0A1L8FWW4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.654
A0A1L8EPZ4	sfrp5	A0A1L8EPZ4	Q8AWG4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 5.	0.658
A0A1L8ES96	A0A1L8GFH0	A0A1L8ES96	A0A1L8GFH0	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.792
A0A1L8ES96	A0A1L8GM33	A0A1L8ES96	A0A1L8GM33	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.792
A0A1L8ES96	A0A1L8GQT6	A0A1L8ES96	A0A1L8GQT6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.889
A0A1L8ES96	Fzd6.S	A0A1L8ES96	A0A1L8FTP5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.411