81 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Slit2.S	Uncharacterized protein. (1530 aa)
	gbx2.1-2	Homeobox protein GBX-2b. (336 aa)
	btg2	B-cell translocation protein 2. (158 aa)
	lep-2	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	Arx2	Aristaless-related homeobox 2. (528 aa)
	gbx2.1	Homeobox domain-containing protein. (340 aa)
	A0A310TQ27	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (851 aa)
	A0A1L8I1U8	Uncharacterized protein. (192 aa)
	Ntrk2.S	Tyrosine-protein kinase receptor. (821 aa)
	Ndnf.L	Uncharacterized protein. (569 aa)
	Rapgef2.L	Uncharacterized protein. (1647 aa)
	A0A1L8HTQ2	Uncharacterized protein. (1521 aa)
	Phox2b	Homeobox domain-containing protein. (293 aa)
	ntrk2	Tyrosine-protein kinase receptor. (807 aa)
	ndnf	Uncharacterized protein. (570 aa)
	A0A1L8HLK0	Uncharacterized protein. (1639 aa)
	Phox2b.S	Homeobox domain-containing protein. (293 aa)
	A0A1L8HIV3	Uncharacterized protein. (729 aa)
	A0A1L8HHE3	Uncharacterized protein. (4632 aa)
	A0A1L8HES3	Uncharacterized protein. (262 aa)
	PAFAH1B1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (435 aa)
	A0A1L8HAK1	Uncharacterized protein. (743 aa)
	Mycbp2.L	Uncharacterized protein. (4632 aa)
	pafah1b1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
	Arx.S	Uncharacterized protein. (527 aa)
	spg11	Spatacsin_C domain-containing protein. (2345 aa)
	lingo1-2	Ig-like domain-containing protein. (606 aa)
	lep	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
	sema3e-2	Sema domain-containing protein; Belongs to the semaphorin family. (276 aa)
	A0A1L8ELE7	Uncharacterized protein. (389 aa)
	A0A1L8EP59	Anion exchange protein. (812 aa)
	gbx2.2	Homeobox domain-containing protein. (340 aa)
	Map2.S	Microtubule-associated protein. (1811 aa)
	nrp2	Neuropilin; Belongs to the neuropilin family. (933 aa)
	B4galt6.L	Uncharacterized protein. (389 aa)
	lrrc45	Uncharacterized protein. (679 aa)
	Slc4a10.L	Anion exchange protein. (1087 aa)
	Gbx2.2.L	Homeobox domain-containing protein. (340 aa)
	Map2.L	Microtubule-associated protein. (1769 aa)
	nrp2-2	Neuropilin; Belongs to the neuropilin family. (934 aa)
	foxg1	Fork-head domain-containing protein. (418 aa)
	A0A1L8F204	Uncharacterized protein. (389 aa)
	A0A1L8F2Q7	Uncharacterized protein. (359 aa)
	A0A1L8F323	Homeobox domain-containing protein. (233 aa)
	arhgap35	Uncharacterized protein. (1476 aa)
	mpp5	Guanylate kinase-like domain-containing protein. (92 aa)
	A0A1L8F6J2	Uncharacterized protein. (389 aa)
	A0A1L8F7J4	Uncharacterized protein. (359 aa)
	A0A1L8F7K0	Uncharacterized protein. (349 aa)
	arhgap35-2	Uncharacterized protein. (1480 aa)
	Foxg1.L	Fork-head domain-containing protein. (436 aa)
	Mpp5.L	Uncharacterized protein; Belongs to the MAGUK family. (675 aa)
	kif1bp	Uncharacterized protein. (613 aa)
	A0A1L8FFM1	Uncharacterized protein. (588 aa)
	Drd2.S	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (437 aa)
	A0A1L8FHR9	Ig-like domain-containing protein. (351 aa)
	A0A1L8FHX0	Uncharacterized protein. (978 aa)
	A0A1L8FK40	Uncharacterized protein. (573 aa)
	A0A1L8FKX2	Uncharacterized protein. (305 aa)
	Drd2.L	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (438 aa)
	scn1b	Ig-like domain-containing protein. (217 aa)
	A0A1L8FSW1	Uncharacterized protein. (383 aa)
	b4galt6	Uncharacterized protein. (383 aa)
	Nr2e1.S	Uncharacterized protein. (386 aa)
	fbxo45	Uncharacterized protein. (280 aa)
	nr2e1	Uncharacterized protein. (386 aa)
	fbxo45-2	Uncharacterized protein. (281 aa)
	lhx8	Uncharacterized protein. (374 aa)
	cdh11	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	lhx8-2	Uncharacterized protein. (374 aa)
	A0A1L8GM41	Uncharacterized protein. (3539 aa)
	A0A1L8GMB2	Pepdidase_M14_N domain-containing protein. (91 aa)
	A0A1L8GMB9	Uncharacterized protein. (126 aa)
	ndnfl1	Uncharacterized protein. (544 aa)
	lingo1	Ig-like domain-containing protein. (606 aa)
	sema3e	Sema domain-containing protein; Belongs to the semaphorin family. (769 aa)
	Scyl2.S	Protein kinase domain-containing protein. (889 aa)
	A0A1L8GV89	Uncharacterized protein. (82 aa)
	ndnfl1.1	Uncharacterized protein. (545 aa)
	scyl2	Protein kinase domain-containing protein. (930 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ELE7	A0A1L8FSW1	A0A1L8ELE7	A0A1L8FSW1	Uncharacterized protein.	Uncharacterized protein.	0.565
A0A1L8ELE7	B4galt6.L	A0A1L8ELE7	A0A1L8ESP9	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8ELE7	b4galt6	A0A1L8ELE7	A0A1L8FYU5	Uncharacterized protein.	Uncharacterized protein.	0.565
A0A1L8F2Q7	A0A1L8HAK1	A0A1L8F2Q7	A0A1L8HAK1	Uncharacterized protein.	Uncharacterized protein.	0.684
A0A1L8F2Q7	A0A1L8HIV3	A0A1L8F2Q7	A0A1L8HIV3	Uncharacterized protein.	Uncharacterized protein.	0.684
A0A1L8F7J4	A0A1L8HAK1	A0A1L8F7J4	A0A1L8HAK1	Uncharacterized protein.	Uncharacterized protein.	0.684
A0A1L8F7J4	A0A1L8HIV3	A0A1L8F7J4	A0A1L8HIV3	Uncharacterized protein.	Uncharacterized protein.	0.684
A0A1L8FSW1	A0A1L8ELE7	A0A1L8FSW1	A0A1L8ELE7	Uncharacterized protein.	Uncharacterized protein.	0.565
A0A1L8FSW1	A0A310TQ27	A0A1L8FSW1	A0A310TQ27	Uncharacterized protein.	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.	0.917
A0A1L8FSW1	B4galt6.L	A0A1L8FSW1	A0A1L8ESP9	Uncharacterized protein.	Uncharacterized protein.	0.565
A0A1L8FSW1	b4galt6	A0A1L8FSW1	A0A1L8FYU5	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8HAK1	A0A1L8F2Q7	A0A1L8HAK1	A0A1L8F2Q7	Uncharacterized protein.	Uncharacterized protein.	0.684
A0A1L8HAK1	A0A1L8F7J4	A0A1L8HAK1	A0A1L8F7J4	Uncharacterized protein.	Uncharacterized protein.	0.684
A0A1L8HAK1	A0A1L8HIV3	A0A1L8HAK1	A0A1L8HIV3	Uncharacterized protein.	Uncharacterized protein.	0.507
A0A1L8HES3	spg11	A0A1L8HES3	A0A1L8H1C5	Uncharacterized protein.	Spatacsin_C domain-containing protein.	0.566
A0A1L8HHE3	fbxo45	A0A1L8HHE3	A0A1L8G4Z9	Uncharacterized protein.	Uncharacterized protein.	0.928
A0A1L8HHE3	fbxo45-2	A0A1L8HHE3	A0A1L8GBA4	Uncharacterized protein.	Uncharacterized protein.	0.928
A0A1L8HIV3	A0A1L8F2Q7	A0A1L8HIV3	A0A1L8F2Q7	Uncharacterized protein.	Uncharacterized protein.	0.684
A0A1L8HIV3	A0A1L8F7J4	A0A1L8HIV3	A0A1L8F7J4	Uncharacterized protein.	Uncharacterized protein.	0.684
A0A1L8HIV3	A0A1L8HAK1	A0A1L8HIV3	A0A1L8HAK1	Uncharacterized protein.	Uncharacterized protein.	0.507