104 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sun1-2	SUN domain-containing protein. (939 aa)
	A0A1L8GF41	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (635 aa)
	Bbs2.S	Uncharacterized protein. (761 aa)
	pax6	Uncharacterized protein. (467 aa)
	mdk	Uncharacterized protein. (142 aa)
	fbxo45-2	Uncharacterized protein. (281 aa)
	A0A1L8G9J6	BRCT domain-containing protein. (154 aa)
	A0A1L8G9I5	BRCT domain-containing protein. (587 aa)
	A0A1L8G9E5	Uncharacterized protein. (181 aa)
	nr2e1	Uncharacterized protein. (386 aa)
	mkks	Uncharacterized protein. (572 aa)
	A0A1L8G773	BTB domain-containing protein. (461 aa)
	pex13	SH3 domain-containing protein. (398 aa)
	fbxo45	Uncharacterized protein. (280 aa)
	A0A1L8G3L5	BRCT domain-containing protein. (453 aa)
	Akirin2.S	Uncharacterized protein. (272 aa)
	Nr2e1.S	Uncharacterized protein. (386 aa)
	A0A1L8G079	Uncharacterized protein. (954 aa)
	A0A1L8FY03	Phosphatase and actin regulator. (641 aa)
	gli3-2	Uncharacterized protein. (1568 aa)
	cdk5r1l	Uncharacterized protein. (293 aa)
	gli3	Uncharacterized protein. (1565 aa)
	Eomes.S	T-box_assoc domain-containing protein. (668 aa)
	htr6	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (422 aa)
	mboat7	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (474 aa)
	A0A1L8FLQ0	Uncharacterized protein. (679 aa)
	Tacc2.L	TACC_C domain-containing protein. (1643 aa)
	A0A1L8FHP2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (407 aa)
	nbl1	CTCK domain-containing protein. (171 aa)
	Bax.L	Uncharacterized protein. (221 aa)
	Pax10a	Homeobox domain-containing protein. (281 aa)
	A0A1L8FGU2	Uncharacterized protein. (77 aa)
	pex5	TPR_REGION domain-containing protein. (619 aa)
	emx2	Homeobox domain-containing protein. (243 aa)
	Mpp5.L	Uncharacterized protein; Belongs to the MAGUK family. (675 aa)
	Foxg1.L	Fork-head domain-containing protein. (436 aa)
	psen1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
	A0A1L8F7K0	Uncharacterized protein. (349 aa)
	A0A1L8F7J4	Uncharacterized protein. (359 aa)
	tsc1-2	Uncharacterized protein. (1102 aa)
	mpp5	Guanylate kinase-like domain-containing protein. (92 aa)
	A0A1L8F323	Homeobox domain-containing protein. (233 aa)
	A0A1L8F2Q7	Uncharacterized protein. (359 aa)
	tsc1	Uncharacterized protein. (1104 aa)
	Ccdc85c.S	Uncharacterized protein. (392 aa)
	A0A1L8EZY9	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
	foxg1	Fork-head domain-containing protein. (418 aa)
	C16orf45.L	BMERB domain-containing protein. (207 aa)
	A0A1L8EX85	RRM domain-containing protein. (292 aa)
	A0A1L8EVZ7	T-box_assoc domain-containing protein. (666 aa)
	cdk5r2	Cyclin-dependent kinase 5 activator. (320 aa)
	A0A1L8ESE2	Uncharacterized protein. (292 aa)
	sun1	SUN domain-containing protein. (939 aa)
	C16orf45.S	BMERB domain-containing protein. (207 aa)
	Tbr1.S	T-box_assoc domain-containing protein. (679 aa)
	A0A1L8EL62	Uncharacterized protein. (292 aa)
	Pax10b	Paired box 10b. (281 aa)
	ctnnb1-2	Ctnnb1-prov protein. (781 aa)
	crkl-2	MGC81407 protein. (302 aa)
	emx2-2	MGC81839 protein. (245 aa)
	efhc1	MGC84469 protein. (552 aa)
	crkl	MGC84382 protein. (302 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	btbd3	BTB domain protein 3. (519 aa)
	cdk5r2-2	Cyclin-dependent kinase 5 activator. (320 aa)
	cdk5r1l-2	Cyclin-dependent kinase 5 regulatory subunit. (293 aa)
	Arx2	Aristaless-related homeobox 2. (528 aa)
	xab2	LOC100036801 protein. (838 aa)
	LOC398065	LOC398065 protein. (666 aa)
	A0A310TMJ6	Uncharacterized protein. (605 aa)
	cep120	Uncharacterized protein. (999 aa)
	Ntrk2.S	Tyrosine-protein kinase receptor. (821 aa)
	mgarp	AIF-MLS domain-containing protein. (550 aa)
	A0A1L8HTQ2	Uncharacterized protein. (1521 aa)
	tacc3-2	TACC_C domain-containing protein. (881 aa)
	A0A1L8HSR8	Homeobox domain-containing protein. (294 aa)
	A0A1L8HRV8	AA_TRNA_LIGASE_II domain-containing protein. (558 aa)
	ntrk2	Tyrosine-protein kinase receptor. (807 aa)
	A0A1L8HLW2	Uncharacterized protein. (5037 aa)
	A0A1L8HLT5	AIF-MLS domain-containing protein. (377 aa)
	Slit2.S	Uncharacterized protein. (1530 aa)
	emx1	Homeobox domain-containing protein. (254 aa)
	nf1	Uncharacterized protein. (2759 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (830 aa)
	PAFAH1B1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (435 aa)
	Crk.L	Uncharacterized protein. (297 aa)
	Nf1.S	Uncharacterized protein. (2774 aa)
	A0A1L8H7W7	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (739 aa)
	pafah1b1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
	crk	Uncharacterized protein. (297 aa)
	Arx.S	Uncharacterized protein. (527 aa)
	tacc1-2	TACC_C domain-containing protein. (636 aa)
	Smo.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
	reln	Uncharacterized protein. (3461 aa)
	Smo.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
	A0A1L8GTC8	TPR_REGION domain-containing protein. (516 aa)
	tacc1	TACC_C domain-containing protein. (572 aa)
	sun2	SUN domain-containing protein. (709 aa)
	A0A1L8GN93	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1598 aa)
	adgrg1	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (642 aa)
	bbs1	BBS1 domain-containing protein. (588 aa)
	pax6-2	Uncharacterized protein. (467 aa)
	Mdk.L	Uncharacterized protein. (173 aa)
	Sun2.S	SUN domain-containing protein. (678 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EX85	xab2	A0A1L8EX85	A0JPH9	RRM domain-containing protein.	LOC100036801 protein.	0.460
A0A1L8EZY9	ctnnb1	A0A1L8EZY9	Q63ZT4	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Beta-catenin protein.	0.986
A0A1L8EZY9	ctnnb1-2	A0A1L8EZY9	Q7ZX35	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Ctnnb1-prov protein.	0.977
A0A1L8EZY9	psen1	A0A1L8EZY9	A0A1L8FAH5	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.900
A0A1L8GTC8	Bbs2.S	A0A1L8GTC8	A0A1L8GEJ7	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.994
A0A1L8GTC8	Smo.L	A0A1L8GTC8	A0A1L8GZN4	TPR_REGION domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.717
A0A1L8GTC8	Smo.S	A0A1L8GTC8	A0A1L8GTP2	TPR_REGION domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.717
A0A1L8GTC8	bbs1	A0A1L8GTC8	A0A1L8GK24	TPR_REGION domain-containing protein.	BBS1 domain-containing protein.	0.997
A0A1L8H7W7	Nr2e1.S	A0A1L8H7W7	A0A1L8G2R9	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Uncharacterized protein.	0.583
A0A1L8H7W7	nr2e1	A0A1L8H7W7	A0A1L8G913	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Uncharacterized protein.	0.583
A0A1L8HLW2	ctnnb1	A0A1L8HLW2	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.636
A0A1L8HLW2	ctnnb1-2	A0A1L8HLW2	Q7ZX35	Uncharacterized protein.	Ctnnb1-prov protein.	0.636
Akirin2.S	emx1	A0A1L8G374	A0A1L8HKA3	Uncharacterized protein.	Homeobox domain-containing protein.	0.471
Bbs2.S	A0A1L8GTC8	A0A1L8GEJ7	A0A1L8GTC8	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.994
Bbs2.S	Smo.L	A0A1L8GEJ7	A0A1L8GZN4	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.728
Bbs2.S	Smo.S	A0A1L8GEJ7	A0A1L8GTP2	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.728
Bbs2.S	bbs1	A0A1L8GEJ7	A0A1L8GK24	Uncharacterized protein.	BBS1 domain-containing protein.	0.997
Bbs2.S	mkks	A0A1L8GEJ7	A0A1L8G7D7	Uncharacterized protein.	Uncharacterized protein.	0.557
Bbs2.S	pex13	A0A1L8GEJ7	A0A1L8G6W9	Uncharacterized protein.	SH3 domain-containing protein.	0.491
Crk.L	crkl	A0A1L8HDP2	Q66KG8	Uncharacterized protein.	MGC84382 protein.	0.634