STRINGSTRING
stat3.1 stat3.1 A0A1L8G9F4 A0A1L8G9F4 A0A1L8G8T2 A0A1L8G8T2 Themis.L Themis.L A0A1L8G7G5 A0A1L8G7G5 srf-2 srf-2 A0A1L8G6C6 A0A1L8G6C6 rsad2 rsad2 Pax1.S Pax1.S A0A1L8G189 A0A1L8G189 srf srf ripk2-2 ripk2-2 A0A1L8FZ33 A0A1L8FZ33 A0A1L8FYE8 A0A1L8FYE8 A0A1L8FXP7 A0A1L8FXP7 ccr9 ccr9 gli3-2 gli3-2 A0A1L8FW11 A0A1L8FW11 Fzd8.L Fzd8.L ripk2 ripk2 A0A1L8FT23 A0A1L8FT23 Bcl2.S Bcl2.S gli3 gli3 Eomes.S Eomes.S A0A1L8FR84 A0A1L8FR84 cd3e-2 cd3e-2 A0A1L8FKW5 A0A1L8FKW5 Nkx2-3.L Nkx2-3.L A0A1L8FIL9 A0A1L8FIL9 Cd3g.S Cd3g.S cd3e cd3e Nkx2-3.S Nkx2-3.S A0A1L8FDY2 A0A1L8FDY2 Rorc.L Rorc.L A0A1L8FD41 A0A1L8FD41 Sema4a.L Sema4a.L Ripk3.S Ripk3.S dll4 dll4 A0A1L8FAA6 A0A1L8FAA6 jag2-2 jag2-2 bcl11b-2 bcl11b-2 batf batf tgfb1-2 tgfb1-2 tsc1-2 tsc1-2 nrarp nrarp Rorc.S Rorc.S A0A1L8F518 A0A1L8F518 sema4a sema4a tgfb1 tgfb1 sash3 sash3 Foxp3.S Foxp3.S abl1 abl1 tsc1 tsc1 Batf.S Batf.S bcl11b bcl11b zbtb1 zbtb1 jag2 jag2 armc5 armc5 A0A1L8EXY7 A0A1L8EXY7 A0A1L8EX75 A0A1L8EX75 A0A1L8EX74 A0A1L8EX74 sp3 sp3 A0A1L8EVP6 A0A1L8EVP6 jmjd6-2 jmjd6-2 tmem98 tmem98 A0A1L8ES01 A0A1L8ES01 Ikzf3.L Ikzf3.L rsad2-2 rsad2-2 Stat3.2.L Stat3.2.L A0A1L8EQA7 A0A1L8EQA7 A0A1L8EQ99 A0A1L8EQ99 fzd5 fzd5 nhej1 nhej1 jmjd6 jmjd6 A0A1L8EKZ0 A0A1L8EKZ0 Ikzf3.S Ikzf3.S A0A1L8EKQ5 A0A1L8EKQ5 Ccr7.S Ccr7.S A0A1L8EKH9 A0A1L8EKH9 rag2 rag2 rag1 rag1 A0A1L8GFI0 A0A1L8GFI0 Rc3h1.S Rc3h1.S abl2 abl2 A0A1L8GGJ1 A0A1L8GGJ1 rag1-2 rag1-2 fadd fadd A0A1L8GKL1 A0A1L8GKL1 A0A1L8GM23 A0A1L8GM23 Rc3h1.L Rc3h1.L Abl2.L Abl2.L A0A1L8GN98 A0A1L8GN98 braf braf IL12B IL12B A0A1L8GR26 A0A1L8GR26 Cd74.S Cd74.S rora rora ncaph2 ncaph2 prr7 prr7 Irf1.S Irf1.S prr7-2 prr7-2 Gata3.L Gata3.L lep lep Ncaph2.L Ncaph2.L rora-2 rora-2 Tp53.L Tp53.L A0A1L8H4Q1 A0A1L8H4Q1 Foxn1.S Foxn1.S rabl3 rabl3 pknox1 pknox1 Sox13.S Sox13.S A0A1L8H7W4 A0A1L8H7W4 Gpr18.S Gpr18.S A0A1L8H9B3 A0A1L8H9B3 A0A1L8H9B5 A0A1L8H9B5 wnt1 wnt1 A0A1L8HA03 A0A1L8HA03 A0A1L8HAR8 A0A1L8HAR8 pknox1-2 pknox1-2 A0A1L8HBZ9 A0A1L8HBZ9 gpr89b gpr89b Foxn1.L Foxn1.L il18r1 il18r1 A0A1L8HGR1 A0A1L8HGR1 Gpr18.L Gpr18.L A0A1L8HH85 A0A1L8HH85 Wnt1.L Wnt1.L A0A1L8HID3 A0A1L8HID3 A0A1L8HKJ9 A0A1L8HKJ9 rhoh rhoh Kit.S Kit.S lef1 lef1 stk11 stk11 A0A1L8HNH2 A0A1L8HNH2 anxa1.2 anxa1.2 Syk.S Syk.S ptger4 ptger4 A0A1L8HRT3 A0A1L8HRT3 A0A1L8HSZ2 A0A1L8HSZ2 rhoh-2 rhoh-2 Kit.L Kit.L stk11-2 stk11-2 A0A1L8HY95 A0A1L8HY95 A0A1L8HYC9 A0A1L8HYC9 syk syk psmb11 psmb11 A0A1L8HZL4 A0A1L8HZL4 ptger4-2 ptger4-2 A0A1L8I2P8 A0A1L8I2P8 G67.L G67.L LOC398065 LOC398065 ccr7 ccr7 sash3-2 sash3-2 sp3-2 sp3-2 xfz8 xfz8 gata3 gata3 lep-2 lep-2 fadd-2 fadd-2 ctnnb1 ctnnb1 anxa1.3 anxa1.3 zap70 zap70 ptpn2 ptpn2 anxa1.1 anxa1.1 lig4 lig4 irf1 irf1 cd74 cd74 anxa1.1-2 anxa1.1-2 ctnnb1-2 ctnnb1-2 lef1-2 lef1-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
stat3.1Signal transducer and activator of transcription. (769 aa)
A0A1L8G9F4Autophagy protein 5; Involved in autophagic vesicle formation. (334 aa)
A0A1L8G8T2SEFIR domain-containing protein. (397 aa)
Themis.LUncharacterized protein. (572 aa)
A0A1L8G7G5Paired domain-containing protein. (437 aa)
srf-2MADS-box domain-containing protein. (448 aa)
A0A1L8G6C6Homeobox domain-containing protein. (387 aa)
rsad2Elp3 domain-containing protein. (350 aa)
Pax1.SPaired domain-containing protein. (449 aa)
A0A1L8G189Homeobox domain-containing protein. (381 aa)
srfMADS-box domain-containing protein. (449 aa)
ripk2-2Uncharacterized protein. (545 aa)
A0A1L8FZ33HMG box domain-containing protein. (537 aa)
A0A1L8FYE8Tyrosine-protein phosphatase non-receptor type. (462 aa)
A0A1L8FXP7BH4_2 domain-containing protein. (300 aa)
ccr9G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (366 aa)
gli3-2Uncharacterized protein. (1568 aa)
A0A1L8FW11Uncharacterized protein. (139 aa)
Fzd8.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
ripk2Uncharacterized protein. (550 aa)
A0A1L8FT23HMG box domain-containing protein. (489 aa)
Bcl2.SBH4_2 domain-containing protein. (253 aa)
gli3Uncharacterized protein. (1565 aa)
Eomes.ST-box_assoc domain-containing protein. (668 aa)
A0A1L8FR84Uncharacterized protein. (220 aa)
cd3e-2Uncharacterized protein. (179 aa)
A0A1L8FKW5Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2533 aa)
Nkx2-3.LHomeobox domain-containing protein. (331 aa)
A0A1L8FIL9Ig-like domain-containing protein. (491 aa)
Cd3g.SIg-like domain-containing protein. (217 aa)
cd3eIGc2 domain-containing protein. (182 aa)
Nkx2-3.SHomeobox domain-containing protein. (335 aa)
A0A1L8FDY2Ig-like domain-containing protein. (467 aa)
Rorc.LUncharacterized protein. (504 aa)
A0A1L8FD41Uncharacterized protein. (428 aa)
Sema4a.LSema domain-containing protein; Belongs to the semaphorin family. (719 aa)
Ripk3.SProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (425 aa)
dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (675 aa)
A0A1L8FAA6Uncharacterized protein. (694 aa)
jag2-2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1227 aa)
bcl11b-2Uncharacterized protein. (809 aa)
batfBZIP domain-containing protein. (115 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
tsc1-2Uncharacterized protein. (1102 aa)
nrarpANK_REP_REGION domain-containing protein. (114 aa)
Rorc.SUncharacterized protein. (465 aa)
A0A1L8F518Fibronectin type-III domain-containing protein. (433 aa)
sema4aSema domain-containing protein; Belongs to the semaphorin family. (742 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
sash3Uncharacterized protein. (391 aa)
Foxp3.SUncharacterized protein. (429 aa)
abl1Tyrosine-protein kinase. (1122 aa)
tsc1Uncharacterized protein. (1104 aa)
Batf.SBZIP domain-containing protein. (115 aa)
bcl11bUncharacterized protein. (810 aa)
zbtb1Uncharacterized protein. (695 aa)
jag2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1223 aa)
armc5BTB domain-containing protein. (934 aa)
A0A1L8EXY7Fibronectin type-III domain-containing protein. (903 aa)
A0A1L8EX75Uncharacterized protein. (1160 aa)
A0A1L8EX74Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
sp3Uncharacterized protein. (717 aa)
A0A1L8EVP6Uncharacterized protein. (289 aa)
jmjd6-2JmjC domain-containing protein. (403 aa)
tmem98Uncharacterized protein. (226 aa)
A0A1L8ES01Uncharacterized protein. (552 aa)
Ikzf3.LUncharacterized protein. (513 aa)
rsad2-2Elp3 domain-containing protein. (363 aa)
Stat3.2.LSignal transducer and activator of transcription. (760 aa)
A0A1L8EQA7Fibronectin type-III domain-containing protein. (866 aa)
A0A1L8EQ99Fibronectin type-III domain-containing protein. (954 aa)
fzd5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
nhej1Uncharacterized protein. (362 aa)
jmjd6JmjC domain-containing protein. (403 aa)
A0A1L8EKZ0Uncharacterized protein. (226 aa)
Ikzf3.SUncharacterized protein. (511 aa)
A0A1L8EKQ5Uncharacterized protein. (534 aa)
Ccr7.SG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (380 aa)
A0A1L8EKH9STAT_int domain-containing protein. (635 aa)
rag2RAG2_PHD domain-containing protein. (520 aa)
rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1045 aa)
A0A1L8GFI0Uncharacterized protein. (848 aa)
Rc3h1.SUncharacterized protein. (1138 aa)
abl2Tyrosine-protein kinase. (1102 aa)
A0A1L8GGJ1Uncharacterized protein. (1173 aa)
rag1-2V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1045 aa)
faddUncharacterized protein. (188 aa)
A0A1L8GKL1Uncharacterized protein. (495 aa)
A0A1L8GM23Uncharacterized protein. (1150 aa)
Rc3h1.LUncharacterized protein. (1114 aa)
Abl2.LTyrosine-protein kinase. (1102 aa)
A0A1L8GN98Uncharacterized protein. (1290 aa)
brafUncharacterized protein. (802 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (316 aa)
A0A1L8GR26HMG box domain-containing protein. (487 aa)
Cd74.SThyroglobulin type-1 domain-containing protein. (302 aa)
roraUncharacterized protein. (461 aa)
ncaph2Uncharacterized protein. (620 aa)
prr7Uncharacterized protein. (262 aa)
Irf1.SInterferon regulatory factor. (345 aa)
prr7-2Uncharacterized protein. (258 aa)
Gata3.LUncharacterized protein. (454 aa)
lepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
Ncaph2.LUncharacterized protein. (624 aa)
rora-2Uncharacterized protein. (464 aa)
Tp53.LP53 domain-containing protein. (137 aa)
A0A1L8H4Q1Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (200 aa)
Foxn1.SFork-head domain-containing protein. (646 aa)
rabl3Uncharacterized protein. (235 aa)
pknox1Homeobox domain-containing protein. (427 aa)
Sox13.SHMG box domain-containing protein. (567 aa)
A0A1L8H7W4Uncharacterized protein. (139 aa)
Gpr18.SG_PROTEIN_RECEP_F1_2 domain-containing protein. (330 aa)
A0A1L8H9B3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (360 aa)
A0A1L8H9B5Uncharacterized protein. (111 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
A0A1L8HA03KRAP_IP3R_bind domain-containing protein. (256 aa)
A0A1L8HAR8Uncharacterized protein. (139 aa)
pknox1-2Homeobox domain-containing protein. (428 aa)
A0A1L8HBZ9Uncharacterized protein. (242 aa)
gpr89bUncharacterized protein. (455 aa)
Foxn1.LFork-head domain-containing protein. (667 aa)
il18r1Uncharacterized protein. (558 aa)
A0A1L8HGR1Uncharacterized protein. (564 aa)
Gpr18.LG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (331 aa)
A0A1L8HH85G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (360 aa)
Wnt1.LProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
A0A1L8HID3KRAP_IP3R_bind domain-containing protein. (255 aa)
A0A1L8HKJ9Ig-like domain-containing protein. (240 aa)
rhohUncharacterized protein. (191 aa)
Kit.SMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
lef1HMG box domain-containing protein. (372 aa)
stk11Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
A0A1L8HNH2Tyrosine-protein kinase. (608 aa)
anxa1.2Annexin. (338 aa)
Syk.STyrosine-protein kinase. (632 aa)
ptger4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (476 aa)
A0A1L8HRT3FN3_7 domain-containing protein. (446 aa)
A0A1L8HSZ2Ig-like domain-containing protein. (235 aa)
rhoh-2Uncharacterized protein. (190 aa)
Kit.LMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
stk11-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
A0A1L8HY95Annexin. (338 aa)
A0A1L8HYC9Annexin. (242 aa)
sykTyrosine-protein kinase. (605 aa)
psmb11Proteasome subunit beta. (276 aa)
A0A1L8HZL4Protein kinase domain-containing protein. (523 aa)
ptger4-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
A0A1L8I2P8Uncharacterized protein. (473 aa)
G67.LUncharacterized protein. (718 aa)
LOC398065LOC398065 protein. (666 aa)
ccr7LOC100036961 protein; Belongs to the G-protein coupled receptor 1 family. (358 aa)
sash3-2LOC100049772 protein. (386 aa)
sp3-2LOC100037013 protein. (724 aa)
xfz8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
gata3XGATA-3 protein. (435 aa)
lep-2Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
fadd-2Fas-associating death domain-containing protein. (188 aa)
ctnnb1Beta-catenin protein. (781 aa)
anxa1.3Annexin. (363 aa)
zap70Tyrosine-protein kinase. (617 aa)
ptpn2Tyrosine-protein phosphatase non-receptor type. (468 aa)
anxa1.1Annexin. (343 aa)
lig4DNA ligase. (911 aa)
irf1Interferon regulatory factor. (298 aa)
cd74MGC68635 protein. (293 aa)
anxa1.1-2Annexin. (343 aa)
ctnnb1-2Ctnnb1-prov protein. (781 aa)
lef1-2Lymphoid enhancer factor XLEF-1. (372 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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