STRINGSTRING
A0A1L8EK96 A0A1L8EK96 A0A1L8EKQ1 A0A1L8EKQ1 A0A1L8ELA2 A0A1L8ELA2 Cebpb.S Cebpb.S A0A1L8EM96 A0A1L8EM96 A0A1L8EMB1 A0A1L8EMB1 trim16 trim16 A0A1L8ENZ6 A0A1L8ENZ6 Frzb.S Frzb.S Klf7.S Klf7.S med1l med1l wnt9b.2 wnt9b.2 Cebpb.L Cebpb.L A0A1L8ETJ3 A0A1L8ETJ3 Mmp9.L Mmp9.L A0A1L8EU06 A0A1L8EU06 Frzb-1 Frzb-1 klf7 klf7 Spred1.S Spred1.S A0A1L8F0V0 A0A1L8F0V0 A0A1L8F2X9 A0A1L8F2X9 tnf tnf spred3 spred3 A0A1L8F4T9 A0A1L8F4T9 F11r.S F11r.S cited1 cited1 A0A1L8F6T4 A0A1L8F6T4 lta-2 lta-2 spred3-2 spred3-2 Spred1.L Spred1.L A0A1L8FCX1 A0A1L8FCX1 Errfi1.S Errfi1.S ajap1 ajap1 A0A1L8FGI1 A0A1L8FGI1 A0A1L8FGS7 A0A1L8FGS7 Pax10a Pax10a tnfrsf1a tnfrsf1a ajap1-2 ajap1-2 A0A1L8FMK1 A0A1L8FMK1 Hes3.1.L Hes3.1.L A0A1L8FN25 A0A1L8FN25 Deltaef1 Deltaef1 Bmp6.S Bmp6.S Rock1.S Rock1.S grhl2 grhl2 Zeb1.S Zeb1.S sfrp4 sfrp4 Med1.L Med1.L bmp6 bmp6 Rock1.L Rock1.L Grhl2.L Grhl2.L jag1 jag1 bmp2 bmp2 dll1 dll1 tp63 tp63 wwtr1 wwtr1 Proc.S Proc.S A0A1L8G4W1 A0A1L8G4W1 grhl1 grhl1 rock2 rock2 Bmp2.L Bmp2.L Jag1.L Jag1.L Ahi1.L Ahi1.L tp63-2 tp63-2 A0A1L8GB68 A0A1L8GB68 Rock2.L Rock2.L A0A1L8GBR0 A0A1L8GBR0 Grhl1.L Grhl1.L pax6 pax6 cdh5 cdh5 apold1 apold1 pax6-2 pax6-2 A0A1L8GJQ1 A0A1L8GJQ1 cdh5-2 cdh5-2 apold1-2 apold1-2 A0A1L8GNU9 A0A1L8GNU9 A0A1L8GPB5 A0A1L8GPB5 cav3.1 cav3.1 nkx6-3 nkx6-3 Smo.S Smo.S Btg1.S Btg1.S Btg1.L Btg1.L Gata3.L Gata3.L Smo.L Smo.L A0A1L8GZR4 A0A1L8GZR4 Il1b.L Il1b.L A0A1L8H1M9 A0A1L8H1M9 Nkx6-3.L Nkx6-3.L ikbkb ikbkb Serpine1.L Serpine1.L Foxn1.S Foxn1.S kdf1 kdf1 Acvrl1.S Acvrl1.S Vdr.L Vdr.L yap1 yap1 numa1 numa1 Foxn1.L Foxn1.L prkx prkx acvrl1 acvrl1 Pax10b Pax10b vdr vdr Yap1.L Yap1.L numa1-2 numa1-2 Atoh8 Atoh8 add1 add1 zdhhc21 zdhhc21 s1pr3 s1pr3 A0A1L8HPW4 A0A1L8HPW4 fst fst Gdnf.S Gdnf.S A0A1L8HSZ7 A0A1L8HSZ7 add1-2 add1-2 spry1 spry1 zdhhc21-2 zdhhc21-2 ptch1 ptch1 s1pr3-2 s1pr3-2 lif lif fst-2 fst-2 Gdnf.L Gdnf.L h2afy h2afy tnf-2 tnf-2 tnfrsf1a-2 tnfrsf1a-2 kdf1-2 kdf1-2 spry1-2 spry1-2 bmp4 bmp4 il1b-A il1b-A mespa mespa X-Delta-2 X-Delta-2 gata3 gata3 f11r f11r wwtr1-2 wwtr1-2 maff maff ctnnb1 ctnnb1 tmem100 tmem100 commd5 commd5 trim16-2 trim16-2 cldn5 cldn5 MGC80637 MGC80637 ptch2 ptch2 cav1a cav1a cav1 cav1 cldn5-2 cldn5-2 mmp9 mmp9 errfi1 errfi1 h2afy2 h2afy2 ctnnb1-2 ctnnb1-2 Cav-3 Cav-3 bmp4-2 bmp4-2 dll1-2 dll1-2 ptch1-2 ptch1-2 ptch2-2 ptch2-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1L8EK96Uncharacterized protein. (127 aa)
A0A1L8EKQ1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa)
A0A1L8ELA2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
Cebpb.SCCAAT/enhancer-binding protein. (288 aa)
A0A1L8EM96ETS domain-containing protein. (363 aa)
A0A1L8EMB1Uncharacterized protein. (683 aa)
trim16Uncharacterized protein. (563 aa)
A0A1L8ENZ6SSD domain-containing protein. (946 aa)
Frzb.SUncharacterized protein. (319 aa)
Klf7.SUncharacterized protein. (293 aa)
med1lMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa)
wnt9b.2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
Cebpb.LCCAAT/enhancer-binding protein. (281 aa)
A0A1L8ETJ3BZIP domain-containing protein. (163 aa)
Mmp9.LUncharacterized protein. (674 aa)
A0A1L8EU06Uncharacterized protein. (574 aa)
Frzb-1Uncharacterized protein. (319 aa)
klf7Uncharacterized protein. (296 aa)
Spred1.SWH1 domain-containing protein. (223 aa)
A0A1L8F0V0Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (650 aa)
A0A1L8F2X9COMM domain-containing protein. (300 aa)
tnfTNF_2 domain-containing protein. (227 aa)
spred3Uncharacterized protein. (422 aa)
A0A1L8F4T9LRAT domain-containing protein. (264 aa)
F11r.SUncharacterized protein. (289 aa)
cited1Uncharacterized protein. (142 aa)
A0A1L8F6T4Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
lta-2TNF_2 domain-containing protein. (208 aa)
spred3-2Uncharacterized protein. (423 aa)
Spred1.LUncharacterized protein. (405 aa)
A0A1L8FCX1Uncharacterized protein. (822 aa)
Errfi1.SInhibitor_Mig-6 domain-containing protein. (404 aa)
ajap1AJAP1_PANP_C domain-containing protein. (391 aa)
A0A1L8FGI1Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (716 aa)
A0A1L8FGS7Uncharacterized protein. (132 aa)
Pax10aHomeobox domain-containing protein. (281 aa)
tnfrsf1aUncharacterized protein. (422 aa)
ajap1-2AJAP1_PANP_C domain-containing protein. (391 aa)
A0A1L8FMK1Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (752 aa)
Hes3.1.LUncharacterized protein. (166 aa)
A0A1L8FN25Uncharacterized protein. (131 aa)
Deltaef1Uncharacterized protein. (1089 aa)
Bmp6.STGF_BETA_2 domain-containing protein. (448 aa)
Rock1.SRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1367 aa)
grhl2CP2 domain-containing protein. (733 aa)
Zeb1.SUncharacterized protein. (919 aa)
sfrp4Uncharacterized protein. (353 aa)
Med1.LMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (649 aa)
bmp6TGF_BETA_2 domain-containing protein. (448 aa)
Rock1.LRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1360 aa)
Grhl2.LCP2 domain-containing protein. (740 aa)
jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1206 aa)
bmp2TGF_BETA_2 domain-containing protein. (398 aa)
dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
tp63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (637 aa)
wwtr1WW domain-containing protein. (390 aa)
Proc.SUncharacterized protein. (455 aa)
A0A1L8G4W1Uncharacterized protein. (347 aa)
grhl1CP2 domain-containing protein. (608 aa)
rock2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1399 aa)
Bmp2.LTGF_BETA_2 domain-containing protein. (398 aa)
Jag1.LDelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
Ahi1.LUncharacterized protein. (1124 aa)
tp63-2Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (636 aa)
A0A1L8GB68Uncharacterized protein. (456 aa)
Rock2.LRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1373 aa)
A0A1L8GBR0Uncharacterized protein. (289 aa)
Grhl1.LCP2 domain-containing protein. (621 aa)
pax6Uncharacterized protein. (467 aa)
cdh5Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (774 aa)
apold1Uncharacterized protein. (222 aa)
pax6-2Uncharacterized protein. (467 aa)
A0A1L8GJQ1Uncharacterized protein. (151 aa)
cdh5-2Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (775 aa)
apold1-2Uncharacterized protein. (218 aa)
A0A1L8GNU9BZIP domain-containing protein. (148 aa)
A0A1L8GPB5Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
cav3.1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
nkx6-3Homeobox domain-containing protein. (254 aa)
Smo.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
Btg1.SAnti_prolifrtn domain-containing protein. (169 aa)
Btg1.LUncharacterized protein. (169 aa)
Gata3.LUncharacterized protein. (454 aa)
Smo.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
A0A1L8GZR4Uncharacterized protein. (318 aa)
Il1b.LInterleukin-1. (145 aa)
A0A1L8H1M9Interleukin-1. (282 aa)
Nkx6-3.LHomeobox domain-containing protein. (254 aa)
ikbkbUncharacterized protein. (769 aa)
Serpine1.LSERPIN domain-containing protein; Belongs to the serpin family. (403 aa)
Foxn1.SFork-head domain-containing protein. (646 aa)
kdf1Uncharacterized protein. (347 aa)
Acvrl1.SReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
Vdr.LUncharacterized protein. (444 aa)
yap1Uncharacterized protein. (457 aa)
numa1Uncharacterized protein. (2302 aa)
Foxn1.LFork-head domain-containing protein. (667 aa)
prkxUncharacterized protein; Belongs to the protein kinase superfamily. (373 aa)
acvrl1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
Pax10bPaired box 10b. (281 aa)
vdrUncharacterized protein. (421 aa)
Yap1.LUncharacterized protein. (459 aa)
numa1-2Uncharacterized protein. (2309 aa)
Atoh8BHLH domain-containing protein. (245 aa)
add1Aldolase_II domain-containing protein. (856 aa)
zdhhc21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (338 aa)
s1pr3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (373 aa)
A0A1L8HPW4Uncharacterized protein. (216 aa)
fstUncharacterized protein. (339 aa)
Gdnf.SGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (227 aa)
A0A1L8HSZ7BHLH domain-containing protein. (292 aa)
add1-2Aldolase_II domain-containing protein. (843 aa)
spry1Uncharacterized protein. (342 aa)
zdhhc21-2Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
ptch1SSD domain-containing protein. (1422 aa)
s1pr3-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (373 aa)
lifUncharacterized protein. (216 aa)
fst-2Uncharacterized protein. (341 aa)
Gdnf.LTGF_BETA_2 domain-containing protein. (332 aa)
h2afyCore histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (369 aa)
tnf-2Tumor necrosis factor alpha. (225 aa)
tnfrsf1a-2Tumor necrosis factor receptor 1. (412 aa)
kdf1-2LOC100137694 protein. (362 aa)
spry1-2Sprouty 1. (319 aa)
bmp4Bone morphogenetic protein 4. (401 aa)
il1b-AInterleukin-1; Belongs to the IL-1 family. (283 aa)
mespaBHLH transcription factor mespa. (283 aa)
X-Delta-2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa)
gata3XGATA-3 protein. (435 aa)
f11rLOC398627 protein. (291 aa)
wwtr1-2LOC496155 protein. (381 aa)
maffLOC495449 protein. (148 aa)
ctnnb1Beta-catenin protein. (781 aa)
tmem100MGC85590 protein. (131 aa)
commd5Commd5-prov protein. (224 aa)
trim16-2MGC84103 protein. (563 aa)
cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)
MGC80637Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)
ptch2SSD domain-containing protein. (1422 aa)
cav1aCaveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
cldn5-2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)
mmp9Gelatinase B. (671 aa)
errfi1MGC68521 protein. (401 aa)
h2afy2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)
ctnnb1-2Ctnnb1-prov protein. (781 aa)
Cav-3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
bmp4-2Bone morphogenetic protein 4. (400 aa)
dll1-2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
ptch1-2Patched-1. (1418 aa)
ptch2-2Patched-2. (1413 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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