(20 nodes) Beta-catenin destruction complex network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	apc	Uncharacterized protein. (2827 aa)
	Apc2.L	Uncharacterized protein. (2148 aa)
	apc-2	Uncharacterized protein. (2834 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	ctnnbip1-2	Ctnnbip1b protein. (81 aa)
	A0A1L8ENI4	Uncharacterized protein. (815 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	A0A1L8EUY4	Uncharacterized protein. (818 aa)
	axin1	Uncharacterized protein. (841 aa)
	gsk3a	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (424 aa)
	A0A1L8FN20	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
	Cacybp.L	Uncharacterized protein. (226 aa)
	A0A1L8H5Q6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	A0A1L8HBT3	Uncharacterized protein. (28 aa)
	A0A1L8HBT4	Protein kinase domain-containing protein. (64 aa)
	A0A1L8HBY8	Protein kinase domain-containing protein. (298 aa)
	A0A1L8HN72	Uncharacterized protein. (2243 aa)
	cacybp	Sip-prov protein. (226 aa)
	ctnnb1-2	Ctnnb1-prov protein. (781 aa)
	ctnnbip1-3	Beta-catenin-interacting protein. (81 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ENI4	A0A1L8FN20	A0A1L8ENI4	A0A1L8FN20	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.808
A0A1L8ENI4	A0A1L8H5Q6	A0A1L8ENI4	A0A1L8H5Q6	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.998
A0A1L8ENI4	A0A1L8HBT3	A0A1L8ENI4	A0A1L8HBT3	Uncharacterized protein.	Uncharacterized protein.	0.786
A0A1L8ENI4	A0A1L8HBT4	A0A1L8ENI4	A0A1L8HBT4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.786
A0A1L8ENI4	A0A1L8HBY8	A0A1L8ENI4	A0A1L8HBY8	Uncharacterized protein.	Protein kinase domain-containing protein.	0.786
A0A1L8ENI4	A0A1L8HN72	A0A1L8ENI4	A0A1L8HN72	Uncharacterized protein.	Uncharacterized protein.	0.932
A0A1L8ENI4	Apc2.L	A0A1L8ENI4	A0A1L8HWG4	Uncharacterized protein.	Uncharacterized protein.	0.944
A0A1L8ENI4	apc	A0A1L8ENI4	A0A1L8HR21	Uncharacterized protein.	Uncharacterized protein.	0.959
A0A1L8ENI4	apc-2	A0A1L8ENI4	A0A1L8I1P0	Uncharacterized protein.	Uncharacterized protein.	0.959
A0A1L8ENI4	ctnnb1	A0A1L8ENI4	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.998
A0A1L8ENI4	ctnnb1-2	A0A1L8ENI4	Q7ZX35	Uncharacterized protein.	Ctnnb1-prov protein.	0.989
A0A1L8ENI4	gsk3a	A0A1L8ENI4	A0A1L8FGT4	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.825
A0A1L8EUY4	A0A1L8FN20	A0A1L8EUY4	A0A1L8FN20	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.808
A0A1L8EUY4	A0A1L8H5Q6	A0A1L8EUY4	A0A1L8H5Q6	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.998
A0A1L8EUY4	A0A1L8HBT3	A0A1L8EUY4	A0A1L8HBT3	Uncharacterized protein.	Uncharacterized protein.	0.786
A0A1L8EUY4	A0A1L8HBT4	A0A1L8EUY4	A0A1L8HBT4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.786
A0A1L8EUY4	A0A1L8HBY8	A0A1L8EUY4	A0A1L8HBY8	Uncharacterized protein.	Protein kinase domain-containing protein.	0.786
A0A1L8EUY4	A0A1L8HN72	A0A1L8EUY4	A0A1L8HN72	Uncharacterized protein.	Uncharacterized protein.	0.932
A0A1L8EUY4	Apc2.L	A0A1L8EUY4	A0A1L8HWG4	Uncharacterized protein.	Uncharacterized protein.	0.944
A0A1L8EUY4	apc	A0A1L8EUY4	A0A1L8HR21	Uncharacterized protein.	Uncharacterized protein.	0.959