39 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8EL97	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (315 aa)
	A0A1L8HF02	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
	A0A1L8HBM1	Homeobox domain-containing protein. (281 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	A0A1L8GYV6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	A0A1L8GV89	Uncharacterized protein. (82 aa)
	A0A1L8GU52	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (333 aa)
	A0A1L8GQT6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	Uchl5.L	Ubiquitin carboxyl-terminal hydrolase. (329 aa)
	uchl5	Ubiquitin carboxyl-terminal hydrolase. (329 aa)
	Tfap2d.L	TF_AP-2 domain-containing protein. (452 aa)
	gdf7	TGF_BETA_2 domain-containing protein. (411 aa)
	ryk	Uncharacterized protein. (596 aa)
	sos1-2	Uncharacterized protein. (1325 aa)
	A0A1L8G5R0	TF_AP-2 domain-containing protein. (454 aa)
	Gdf7.S	TGF_BETA_2 domain-containing protein. (413 aa)
	fzd3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	A0A1L8G548	Uncharacterized protein. (465 aa)
	sos1	Uncharacterized protein. (1325 aa)
	A0A1L8G0R4	Homeobox domain-containing protein. (327 aa)
	en2	Homeobox protein engrailed-like. (265 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	A0A1L8FQD6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
	A0A1L8ESG7	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	wnt9b.2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	en1	Homeobox protein engrailed-like. (228 aa)
	A0A1L8ELA2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	ctnnb1-2	Ctnnb1-prov protein. (781 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	en1-2	Homeobox protein engrailed-like. (229 aa)
	otx1	Otx1-A protein. (338 aa)
	fz3	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	en2-2	Homeobox protein engrailed-like. (265 aa)
	msx1-2	LOC100125666 protein. (273 aa)
	A0A1L8HXZ2	BHLH domain-containing protein. (115 aa)
	A0A1L8HUK7	Mothers against decapentaplegic homolog. (422 aa)
	A0A1L8HNZ8	BHLH domain-containing protein. (115 aa)
	msx1	Homeobox domain-containing protein. (275 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EL97	A0A1L8ELA2	A0A1L8EL97	A0A1L8ELA2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.419
A0A1L8EL97	A0A1L8G548	A0A1L8EL97	A0A1L8G548	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.602
A0A1L8EL97	A0A1L8GQT6	A0A1L8EL97	A0A1L8GQT6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.768
A0A1L8EL97	Wnt1.L	A0A1L8EL97	A0A1L8HHR8	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.464
A0A1L8EL97	ctnnb1	A0A1L8EL97	Q63ZT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Beta-catenin protein.	0.471
A0A1L8EL97	ctnnb1-2	A0A1L8EL97	Q7ZX35	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Ctnnb1-prov protein.	0.471
A0A1L8EL97	ryk	A0A1L8EL97	A0A1L8GB75	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.602
A0A1L8EL97	wnt1	A0A1L8EL97	A0A1L8H9S8	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.464
A0A1L8EL97	wnt9b.2	A0A1L8EL97	A0A1L8ESG2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.419
A0A1L8ELA2	A0A1L8EL97	A0A1L8ELA2	A0A1L8EL97	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.419
A0A1L8ELA2	A0A1L8ESG7	A0A1L8ELA2	A0A1L8ESG7	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.419
A0A1L8ELA2	A0A1L8FQD6	A0A1L8ELA2	A0A1L8FQD6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.419
A0A1L8ELA2	A0A1L8G548	A0A1L8ELA2	A0A1L8G548	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.413
A0A1L8ELA2	A0A1L8GQT6	A0A1L8ELA2	A0A1L8GQT6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.810
A0A1L8ELA2	A0A1L8GU52	A0A1L8ELA2	A0A1L8GU52	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.453
A0A1L8ELA2	A0A1L8GYV6	A0A1L8ELA2	A0A1L8GYV6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.451
A0A1L8ELA2	A0A1L8HF02	A0A1L8ELA2	A0A1L8HF02	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.466
A0A1L8ELA2	Wnt1.L	A0A1L8ELA2	A0A1L8HHR8	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.517
A0A1L8ELA2	fz3	A0A1L8ELA2	B7ZQS8	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.759
A0A1L8ELA2	fzd3	A0A1L8ELA2	A0A1L8G5I1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.759