18 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdca7	zf-4CXXC_R1 domain-containing protein. (431 aa)
	Eme1.L	ERCC4 domain-containing protein. (411 aa)
	eme2	ERCC4 domain-containing protein. (500 aa)
	nek11	Protein kinase domain-containing protein. (599 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (932 aa)
	mus81	ERCC4 domain-containing protein. (613 aa)
	fancd2	Uncharacterized protein. (1445 aa)
	xpc	Uncharacterized protein. (1062 aa)
	Tipin.S	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (361 aa)
	tipin	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (362 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (711 aa)
	A0A1L8HRA7	Uncharacterized protein. (177 aa)
	A0A1L8I081	Uncharacterized protein. (96 aa)
	Chek2.L	Uncharacterized protein. (392 aa)
	rad9b	Cell cycle checkpoint control protein; Belongs to the rad9 family. (483 aa)
	Rad17.L	Uncharacterized protein. (674 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8HRA7	A0A1L8I081	A0A1L8HRA7	A0A1L8I081	Uncharacterized protein.	Uncharacterized protein.	0.634
A0A1L8HRA7	Chek2.L	A0A1L8HRA7	A0A1L8I0A0	Uncharacterized protein.	Uncharacterized protein.	0.634
A0A1L8HRA7	Hus1	A0A1L8HRA7	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.990
A0A1L8HRA7	Tipin.S	A0A1L8HRA7	A0A1L8GSF3	Uncharacterized protein.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.655
A0A1L8HRA7	cdca7	A0A1L8HRA7	A0A1L8EPB1	Uncharacterized protein.	zf-4CXXC_R1 domain-containing protein.	0.960
A0A1L8HRA7	mre11	A0A1L8HRA7	A0A1L8HJD9	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.891
A0A1L8HRA7	mus81	A0A1L8HRA7	A0A1L8GJY4	Uncharacterized protein.	ERCC4 domain-containing protein.	0.691
A0A1L8HRA7	rad9a	A0A1L8HRA7	Q7ZZU5	Uncharacterized protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.981
A0A1L8HRA7	rad9b	A0A1L8HRA7	A0A1L8I188	Uncharacterized protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.981
A0A1L8HRA7	tipin	A0A1L8HRA7	A0A1L8H168	Uncharacterized protein.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.655
A0A1L8I081	A0A1L8HRA7	A0A1L8I081	A0A1L8HRA7	Uncharacterized protein.	Uncharacterized protein.	0.634
A0A1L8I081	Hus1	A0A1L8I081	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.586
A0A1L8I081	Rad17.L	A0A1L8I081	A0A1L8I1Y0	Uncharacterized protein.	Uncharacterized protein.	0.634
A0A1L8I081	Tipin.S	A0A1L8I081	A0A1L8GSF3	Uncharacterized protein.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.633
A0A1L8I081	cdca7	A0A1L8I081	A0A1L8EPB1	Uncharacterized protein.	zf-4CXXC_R1 domain-containing protein.	0.611
A0A1L8I081	fancd2	A0A1L8I081	A0A1L8GP71	Uncharacterized protein.	Uncharacterized protein.	0.426
A0A1L8I081	mre11	A0A1L8I081	A0A1L8HJD9	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.838
A0A1L8I081	msh2	A0A1L8I081	A0A1L8G6D6	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.701
A0A1L8I081	mus81	A0A1L8I081	A0A1L8GJY4	Uncharacterized protein.	ERCC4 domain-containing protein.	0.877
A0A1L8I081	rad9a	A0A1L8I081	Q7ZZU5	Uncharacterized protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.611