20 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cd40lg.S	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (273 aa)
	Cebpb.S	CCAAT/enhancer-binding protein. (288 aa)
	Cebpb.L	CCAAT/enhancer-binding protein. (281 aa)
	Foxp3.S	Uncharacterized protein. (429 aa)
	sash3	Uncharacterized protein. (391 aa)
	slc7a5	MGC68975 protein. (507 aa)
	timd4	MGC99322 protein. (224 aa)
	gata3	XGATA-3 protein. (435 aa)
	sash3-2	LOC100049772 protein. (386 aa)
	syk	Tyrosine-protein kinase. (605 aa)
	Syk.S	Tyrosine-protein kinase. (632 aa)
	Gata3.L	Uncharacterized protein. (454 aa)
	A0A1L8GBB3	Uncharacterized protein. (327 aa)
	il1rap	Uncharacterized protein. (690 aa)
	Fcrg2	Uncharacterized protein. (163 aa)
	A0A1L8FCS0	NACHT domain-containing protein. (883 aa)
	A0A1L8FCQ3	NACHT domain-containing protein. (883 aa)
	A0A1L8FCP4	NACHT domain-containing protein. (882 aa)
	cd40lg	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (279 aa)
	A0A1L8F4Z8	Uncharacterized protein. (65 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F4Z8	Fcrg2	A0A1L8F4Z8	A0A1L8FD19	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A1L8F4Z8	Syk.S	A0A1L8F4Z8	A0A1L8HPI7	Uncharacterized protein.	Tyrosine-protein kinase.	0.994
A0A1L8F4Z8	syk	A0A1L8F4Z8	A0A1L8HYI7	Uncharacterized protein.	Tyrosine-protein kinase.	0.995
Cd40lg.S	Foxp3.S	A0A1L8F3A9	A0A1L8F1I8	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Uncharacterized protein.	0.525
Cd40lg.S	cd40lg	A0A1L8F3A9	A0A1L8F817	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.900
Cd40lg.S	timd4	A0A1L8F3A9	Q66GV2	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	MGC99322 protein.	0.414
Cebpb.L	Gata3.L	A0A1L8ESS1	A0A1L8GZI0	CCAAT/enhancer-binding protein.	Uncharacterized protein.	0.457
Cebpb.L	gata3	A0A1L8ESS1	Q2TAR8	CCAAT/enhancer-binding protein.	XGATA-3 protein.	0.457
Cebpb.S	Gata3.L	A0A1L8ELB5	A0A1L8GZI0	CCAAT/enhancer-binding protein.	Uncharacterized protein.	0.448
Cebpb.S	gata3	A0A1L8ELB5	Q2TAR8	CCAAT/enhancer-binding protein.	XGATA-3 protein.	0.448
Fcrg2	A0A1L8F4Z8	A0A1L8FD19	A0A1L8F4Z8	Uncharacterized protein.	Uncharacterized protein.	0.901
Fcrg2	Syk.S	A0A1L8FD19	A0A1L8HPI7	Uncharacterized protein.	Tyrosine-protein kinase.	0.994
Fcrg2	syk	A0A1L8FD19	A0A1L8HYI7	Uncharacterized protein.	Tyrosine-protein kinase.	0.994
Foxp3.S	Cd40lg.S	A0A1L8F1I8	A0A1L8F3A9	Uncharacterized protein.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.525
Foxp3.S	Gata3.L	A0A1L8F1I8	A0A1L8GZI0	Uncharacterized protein.	Uncharacterized protein.	0.695
Foxp3.S	cd40lg	A0A1L8F1I8	A0A1L8F817	Uncharacterized protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.435
Foxp3.S	gata3	A0A1L8F1I8	Q2TAR8	Uncharacterized protein.	XGATA-3 protein.	0.695
Foxp3.S	timd4	A0A1L8F1I8	Q66GV2	Uncharacterized protein.	MGC99322 protein.	0.575
Gata3.L	Cebpb.L	A0A1L8GZI0	A0A1L8ESS1	Uncharacterized protein.	CCAAT/enhancer-binding protein.	0.457
Gata3.L	Cebpb.S	A0A1L8GZI0	A0A1L8ELB5	Uncharacterized protein.	CCAAT/enhancer-binding protein.	0.448