79 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8GG25	Uncharacterized protein. (1252 aa)
	A0A1L8EJY7	Uncharacterized protein. (68 aa)
	A0A1L8EML9	Uncharacterized protein. (156 aa)
	A0A1L8EU83	Uncharacterized protein. (156 aa)
	ifih1	Uncharacterized protein. (996 aa)
	hspd1	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (576 aa)
	card9	CARD domain-containing protein. (527 aa)
	tnf	TNF_2 domain-containing protein. (227 aa)
	Arhgef2.S	Uncharacterized protein. (1003 aa)
	A0A1L8F518	Fibronectin type-III domain-containing protein. (433 aa)
	card9-2	CARD domain-containing protein. (527 aa)
	arhgef2	Uncharacterized protein. (984 aa)
	A0A1L8FD41	Uncharacterized protein. (428 aa)
	Pou2af1.S	Uncharacterized protein. (257 aa)
	A0A1L8FHP3	TIR domain-containing protein. (476 aa)
	A0A1L8FL04	TIR domain-containing protein. (213 aa)
	A0A1L8FL21	TIR domain-containing protein. (202 aa)
	Pou2af1.L	Uncharacterized protein. (267 aa)
	A0A1L8FPF3	TIR domain-containing protein. (270 aa)
	Myd88.S	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
	A0A1L8FR84	Uncharacterized protein. (220 aa)
	nod1	Uncharacterized protein. (946 aa)
	ripk2	Uncharacterized protein. (550 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (283 aa)
	A0A1L8FW11	Uncharacterized protein. (139 aa)
	mbp	Uncharacterized protein. (308 aa)
	ripk2-2	Uncharacterized protein. (545 aa)
	Akirin2.S	Uncharacterized protein. (272 aa)
	A0A1L8G9E5	Uncharacterized protein. (181 aa)
	il1rap	Uncharacterized protein. (690 aa)
	A0A1L8GC99	Uncharacterized protein. (163 aa)
	C1qtnf4.S	Uncharacterized protein. (418 aa)
	Traf6.S	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
	Il17rc.S	SEFIR domain-containing protein. (468 aa)
	Traf6.L	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
	A0A1L8GJ05	Uncharacterized protein. (363 aa)
	A0A1L8GKF8	Uncharacterized protein. (1010 aa)
	A0A1L8GKL1	Uncharacterized protein. (495 aa)
	Cyba.L	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (187 aa)
	A0A1L8GMQ0	Uncharacterized protein. (1244 aa)
	tlr9	TIR domain-containing protein; Belongs to the Toll-like receptor family. (830 aa)
	A0A1L8GQ28	SEFIR domain-containing protein. (764 aa)
	A0A1L8GQR1	SEFIR domain-containing protein. (645 aa)
	Cd74.S	Thyroglobulin type-1 domain-containing protein. (302 aa)
	IL16	Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1294 aa)
	A0A1L8GUI6	Uncharacterized protein. (183 aa)
	ifng	Uncharacterized protein. (182 aa)
	lep	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
	il16	Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1295 aa)
	Il1b.L	Interleukin-1. (145 aa)
	A0A1L8H1M9	Interleukin-1. (282 aa)
	A0A1L8H564	BPTI/Kunitz inhibitor domain-containing protein. (751 aa)
	zbtb20	Uncharacterized protein. (750 aa)
	rab7b	Uncharacterized protein. (201 aa)
	zbtb20-2	Uncharacterized protein. (768 aa)
	Setd4.L	SET domain-containing protein. (456 aa)
	App.L	BPTI/Kunitz inhibitor domain-containing protein. (749 aa)
	A0A1L8HEQ1	Uncharacterized protein. (122 aa)
	A0A1L8HES6	Uncharacterized protein. (553 aa)
	A0A1L8HGH7	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1036 aa)
	A0A1L8HGJ7	LRRCT domain-containing protein. (911 aa)
	A0A1L8HGQ4	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1051 aa)
	A0A1L8HKI7	CARD_2 domain-containing protein. (384 aa)
	spon2	Spondin domain-containing protein. (345 aa)
	ereg	Uncharacterized protein. (156 aa)
	Syk.S	Tyrosine-protein kinase. (632 aa)
	A0A1L8HQW3	BZIP domain-containing protein. (433 aa)
	spon2-2	Spondin domain-containing protein. (345 aa)
	A0A1L8HTX4	TIR domain-containing protein; Belongs to the Toll-like receptor family. (896 aa)
	ereg-2	Uncharacterized protein. (156 aa)
	syk	Tyrosine-protein kinase. (605 aa)
	A0A1L8I199	BZIP domain-containing protein. (390 aa)
	tnf-2	Tumor necrosis factor alpha. (225 aa)
	mbp-2	Golli protein J37.1. (306 aa)
	il1b-A	Interleukin-1; Belongs to the IL-1 family. (283 aa)
	lep-2	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
	rab7b-2	MGC80651 protein. (201 aa)
	hspd1-2	Hspd1 protein; Belongs to the chaperonin (HSP60) family. (579 aa)
	cd74	MGC68635 protein. (293 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EJY7	A0A1L8HKI7	A0A1L8EJY7	A0A1L8HKI7	Uncharacterized protein.	CARD_2 domain-containing protein.	0.556
A0A1L8EJY7	Myd88.S	A0A1L8EJY7	A0A1L8FQF6	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.734
A0A1L8EJY7	myd88	A0A1L8EJY7	A0A1L8FV26	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.734
A0A1L8EML9	A0A1L8GQR1	A0A1L8EML9	A0A1L8GQR1	Uncharacterized protein.	SEFIR domain-containing protein.	0.408
A0A1L8EU83	A0A1L8GQR1	A0A1L8EU83	A0A1L8GQR1	Uncharacterized protein.	SEFIR domain-containing protein.	0.408
A0A1L8F518	A0A1L8FD41	A0A1L8F518	A0A1L8FD41	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.901
A0A1L8F518	A0A1L8FR84	A0A1L8F518	A0A1L8FR84	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.979
A0A1L8F518	A0A1L8FW11	A0A1L8F518	A0A1L8FW11	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.997
A0A1L8F518	A0A1L8H1M9	A0A1L8F518	A0A1L8H1M9	Fibronectin type-III domain-containing protein.	Interleukin-1.	0.427
A0A1L8F518	Il1b.L	A0A1L8F518	A0A1L8H1M6	Fibronectin type-III domain-containing protein.	Interleukin-1.	0.427
A0A1L8F518	il1b-A	A0A1L8F518	B7ZSG9	Fibronectin type-III domain-containing protein.	Interleukin-1; Belongs to the IL-1 family.	0.427
A0A1L8FD41	A0A1L8F518	A0A1L8FD41	A0A1L8F518	Uncharacterized protein.	Fibronectin type-III domain-containing protein.	0.901
A0A1L8FD41	A0A1L8FR84	A0A1L8FD41	A0A1L8FR84	Uncharacterized protein.	Uncharacterized protein.	0.979
A0A1L8FD41	A0A1L8FW11	A0A1L8FD41	A0A1L8FW11	Uncharacterized protein.	Uncharacterized protein.	0.997
A0A1L8FD41	A0A1L8H1M9	A0A1L8FD41	A0A1L8H1M9	Uncharacterized protein.	Interleukin-1.	0.427
A0A1L8FD41	Il1b.L	A0A1L8FD41	A0A1L8H1M6	Uncharacterized protein.	Interleukin-1.	0.427
A0A1L8FD41	il1b-A	A0A1L8FD41	B7ZSG9	Uncharacterized protein.	Interleukin-1; Belongs to the IL-1 family.	0.427
A0A1L8FHP3	A0A1L8HTX4	A0A1L8FHP3	A0A1L8HTX4	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.601
A0A1L8FHP3	Myd88.S	A0A1L8FHP3	A0A1L8FQF6	TIR domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.784
A0A1L8FHP3	Traf6.L	A0A1L8FHP3	A0A1L8GIM0	TIR domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.603