50 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8FJ40	FHA domain-containing protein. (1959 aa)
	A0A1L8FED4	FHA domain-containing protein. (2230 aa)
	bag3	Uncharacterized protein. (527 aa)
	Hsp90alpha	HATPase_c domain-containing protein. (729 aa)
	Daxx.L	Daxx domain-containing protein. (911 aa)
	ier5l	Uncharacterized protein. (293 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	Nf1.S	Uncharacterized protein. (2774 aa)
	Trpv1.S	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (838 aa)
	tcim-2	TC1 domain-containing protein. (96 aa)
	A0A1L8GYW0	BHLH domain-containing protein. (369 aa)
	fgf1-2	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	slu7	Slu7 domain-containing protein. (580 aa)
	A0A1L8GVX6	Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (329 aa)
	fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (156 aa)
	A0A1L8GU88	BHLH domain-containing protein. (304 aa)
	tcim	TC1 domain-containing protein. (96 aa)
	A0A1L8GQ72	Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (264 aa)
	A0A1L8GNN2	Uncharacterized protein. (423 aa)
	Ier5.L	Uncharacterized protein. (313 aa)
	A0A1L8GL11	Uncharacterized protein. (119 aa)
	tpr	TPR_MLP1_2 domain-containing protein. (2321 aa)
	A0A1L8GF50	Uncharacterized protein. (117 aa)
	dhx36-2	Uncharacterized protein. (1000 aa)
	A0A1L8G6W7	HATPase_c domain-containing protein. (634 aa)
	dhx36	Uncharacterized protein. (977 aa)
	trpv4l-2	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (815 aa)
	trpv4l	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (721 aa)
	lyn-2	Tyrosine-protein kinase. (508 aa)
	lyn	Tyrosine-protein kinase. (508 aa)
	A0A1L8FSH3	Uncharacterized protein. (103 aa)
	bag3-2	Bag3-A protein. (597 aa)
	ier5	MGC81179 protein. (280 aa)
	hsp90ab1	Hsp90beta protein. (722 aa)
	polr2d	MGC85403 protein. (142 aa)
	ywhae	14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
	A0A310TNB9	Uncharacterized protein. (285 aa)
	A0A1L8I3S6	Uncharacterized protein; Belongs to the AAA ATPase family. (746 aa)
	trpv4-2	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (867 aa)
	Vcp.S	Uncharacterized protein; Belongs to the AAA ATPase family. (805 aa)
	trpv4	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (868 aa)
	htra2	PDZ domain-containing protein. (407 aa)
	A0A1L8HJG3	ANK_REP_REGION domain-containing protein. (598 aa)
	hikeshi	DUF775 domain-containing protein. (197 aa)
	nf1	Uncharacterized protein. (2759 aa)
	A0A1L8HDP1	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (233 aa)
	trpv1	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (832 aa)
	Trpv3.L	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (719 aa)
	trpv3	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (746 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FSH3	A0A1L8G6W7	A0A1L8FSH3	A0A1L8G6W7	Uncharacterized protein.	HATPase_c domain-containing protein.	0.436
A0A1L8FSH3	Hsp90alpha	A0A1L8FSH3	A0A1L8F9X7	Uncharacterized protein.	HATPase_c domain-containing protein.	0.436
A0A1L8FSH3	hsp90ab1	A0A1L8FSH3	Q6AZV1	Uncharacterized protein.	Hsp90beta protein.	0.436
A0A1L8G6W7	A0A1L8FSH3	A0A1L8G6W7	A0A1L8FSH3	HATPase_c domain-containing protein.	Uncharacterized protein.	0.436
A0A1L8G6W7	A0A1L8GF50	A0A1L8G6W7	A0A1L8GF50	HATPase_c domain-containing protein.	Uncharacterized protein.	0.563
A0A1L8G6W7	A0A1L8GL11	A0A1L8G6W7	A0A1L8GL11	HATPase_c domain-containing protein.	Uncharacterized protein.	0.563
A0A1L8G6W7	A0A1L8HDP1	A0A1L8G6W7	A0A1L8HDP1	HATPase_c domain-containing protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.413
A0A1L8G6W7	A0A1L8HJG3	A0A1L8G6W7	A0A1L8HJG3	HATPase_c domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.804
A0A1L8G6W7	A0A1L8I3S6	A0A1L8G6W7	A0A1L8I3S6	HATPase_c domain-containing protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.614
A0A1L8G6W7	Vcp.S	A0A1L8G6W7	A0A1L8HSA2	HATPase_c domain-containing protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.614
A0A1L8G6W7	lyn	A0A1L8G6W7	A0A1L8FT48	HATPase_c domain-containing protein.	Tyrosine-protein kinase.	0.515
A0A1L8G6W7	lyn-2	A0A1L8G6W7	A0A1L8FZ11	HATPase_c domain-containing protein.	Tyrosine-protein kinase.	0.515
A0A1L8G6W7	ywhae	A0A1L8G6W7	O57468	HATPase_c domain-containing protein.	14-3-3 protein epsilon; Belongs to the 14-3-3 family.	0.413
A0A1L8GF50	A0A1L8G6W7	A0A1L8GF50	A0A1L8G6W7	Uncharacterized protein.	HATPase_c domain-containing protein.	0.563
A0A1L8GF50	Hsp90alpha	A0A1L8GF50	A0A1L8F9X7	Uncharacterized protein.	HATPase_c domain-containing protein.	0.563
A0A1L8GF50	hsp90ab1	A0A1L8GF50	Q6AZV1	Uncharacterized protein.	Hsp90beta protein.	0.563
A0A1L8GL11	A0A1L8G6W7	A0A1L8GL11	A0A1L8G6W7	Uncharacterized protein.	HATPase_c domain-containing protein.	0.563
A0A1L8GL11	Hsp90alpha	A0A1L8GL11	A0A1L8F9X7	Uncharacterized protein.	HATPase_c domain-containing protein.	0.563
A0A1L8GL11	hsp90ab1	A0A1L8GL11	Q6AZV1	Uncharacterized protein.	Hsp90beta protein.	0.563
A0A1L8GNN2	Sumo1.L	A0A1L8GNN2	A0A1L8EWZ5	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.565