STRINGSTRING
Hif1an.L Hif1an.L pick1 pick1 egln3 egln3 suv39h2-2 suv39h2-2 Stox1.L Stox1.L A0A310TVP4 A0A310TVP4 Hyou1.S Hyou1.S Ndnf.L Ndnf.L mgarp mgarp rbpj rbpj A0A1L8HTE0 A0A1L8HTE0 A0A1L8HSZ3 A0A1L8HSZ3 ndnf ndnf A0A1L8HLT5 A0A1L8HLT5 Rbpj.S Rbpj.S A0A1L8HKV6 A0A1L8HKV6 fabp1 fabp1 A0A1L8HHH0 A0A1L8HHH0 oprd1-2 oprd1-2 slc9a1 slc9a1 A0A1L8HDH0 A0A1L8HDH0 Tbl2.L Tbl2.L bach1-2 bach1-2 Rgcc.S Rgcc.S oprd1 oprd1 Slc9a1.S Slc9a1.S Mdm4.S Mdm4.S Ppard.S Ppard.S A0A1L8H6C5 A0A1L8H6C5 A0A1L8H5T0 A0A1L8H5T0 bach1 bach1 tbl2 tbl2 A0A1L8H4Q1 A0A1L8H4Q1 Tp53.L Tp53.L Nkx3-1.L Nkx3-1.L Cpeb1.L Cpeb1.L ndnfl1.1 ndnfl1.1 suv39h2 suv39h2 cpeb1 cpeb1 A0A1L8GRY7 A0A1L8GRY7 tert tert hif1a hif1a bnip3-2 bnip3-2 nkx3-1 nkx3-1 ndnfl1 ndnfl1 Tigar.S Tigar.S vhl vhl A0A1L8GNX0 A0A1L8GNX0 Atf4.L Atf4.L ddr2-2 ddr2-2 A0A1L8GNN4 A0A1L8GNN4 C-Mpl C-Mpl ak4-2 ak4-2 A0A1L8GJQ1 A0A1L8GJQ1 A0A1L8GHJ8 A0A1L8GHJ8 A0A1L8GHI4 A0A1L8GHI4 Ptgs2.S Ptgs2.S Atf4.S Atf4.S ddr2 ddr2 ak4 ak4 Fndc1.L Fndc1.L kcnk2 kcnk2 Epas1.L Epas1.L Egln1.S Egln1.S fndc1 fndc1 epas1 epas1 A0A1L8G198 A0A1L8G198 Ndrg1.L Ndrg1.L A0A1L8FYS5 A0A1L8FYS5 A0A1L8FXP7 A0A1L8FXP7 Aqp1.L Aqp1.L ndrg1 ndrg1 Myc.S Myc.S A0A1L8FTT4 A0A1L8FTT4 gata6 gata6 Bcl2.S Bcl2.S Aqp1.S Aqp1.S hyou1 hyou1 A0A1L8FKW5 A0A1L8FKW5 nfe2l2 nfe2l2 Sirt1.L Sirt1.L bnip3 bnip3 Ado.L Ado.L Sirt2.S Sirt2.S sirt1 sirt1 stox1 stox1 ado ado nop53 nop53 egln2-2 egln2-2 aifm1 aifm1 tsc1-2 tsc1-2 Suv39h1.L Suv39h1.L Egln3.S Egln3.S suv39h1 suv39h1 egln2 egln2 tsc1 tsc1 ddr2l ddr2l Hif-1a Hif-1a A0A1L8EY00 A0A1L8EY00 npepps-2 npepps-2 A0A1L8EQI2 A0A1L8EQI2 Nfe2l2.S Nfe2l2.S npepps npepps A0A1L8EKE6 A0A1L8EKE6 myc myc hif1an hif1an
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hif1an.LJmjC domain-containing protein. (350 aa)
pick1MGC131295 protein. (405 aa)
egln3LOC100127282 protein. (252 aa)
suv39h2-2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (406 aa)
Stox1.LStork_head domain-containing protein. (981 aa)
A0A310TVP4F5/8 type C domain-containing protein. (87 aa)
Hyou1.SUncharacterized protein. (989 aa)
Ndnf.LUncharacterized protein. (569 aa)
mgarpAIF-MLS domain-containing protein. (550 aa)
rbpjUncharacterized protein. (487 aa)
A0A1L8HTE0Uncharacterized protein. (809 aa)
A0A1L8HSZ3FABP domain-containing protein. (127 aa)
ndnfUncharacterized protein. (570 aa)
A0A1L8HLT5AIF-MLS domain-containing protein. (377 aa)
Rbpj.SUncharacterized protein. (485 aa)
A0A1L8HKV6Uncharacterized protein. (781 aa)
fabp1FABP domain-containing protein. (127 aa)
A0A1L8HHH0Uncharacterized protein. (128 aa)
oprd1-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (373 aa)
slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (773 aa)
A0A1L8HDH0Protein-serine/threonine kinase. (404 aa)
Tbl2.LWD_REPEATS_REGION domain-containing protein. (436 aa)
bach1-2Uncharacterized protein. (715 aa)
Rgcc.SUncharacterized protein. (162 aa)
oprd1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (373 aa)
Slc9a1.SSodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (774 aa)
Mdm4.SRanBP2-type domain-containing protein. (423 aa)
Ppard.SUncharacterized protein. (336 aa)
A0A1L8H6C5NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (418 aa)
A0A1L8H5T0Protein-serine/threonine kinase. (405 aa)
bach1BZIP domain-containing protein. (651 aa)
tbl2WD_REPEATS_REGION domain-containing protein. (436 aa)
A0A1L8H4Q1Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (200 aa)
Tp53.LP53 domain-containing protein. (137 aa)
Nkx3-1.LHomeobox domain-containing protein. (213 aa)
Cpeb1.LUncharacterized protein. (568 aa)
ndnfl1.1Uncharacterized protein. (545 aa)
suv39h2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
cpeb1Uncharacterized protein. (568 aa)
A0A1L8GRY7Uncharacterized protein. (183 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1191 aa)
hif1aHif1a-prov protein. (802 aa)
bnip3-2MGC68574 protein. (202 aa)
nkx3-1Homeobox domain-containing protein. (213 aa)
ndnfl1Uncharacterized protein. (544 aa)
Tigar.SUncharacterized protein. (275 aa)
vhlUncharacterized protein. (165 aa)
A0A1L8GNX0Uncharacterized protein; Belongs to the complex I LYR family. (70 aa)
Atf4.LBZIP domain-containing protein. (343 aa)
ddr2-2Uncharacterized protein. (885 aa)
A0A1L8GNN4EGF-like domain-containing protein. (604 aa)
C-MplUncharacterized protein. (583 aa)
ak4-2GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (231 aa)
A0A1L8GJQ1Uncharacterized protein. (151 aa)
A0A1L8GHJ8Uncharacterized protein. (165 aa)
A0A1L8GHI4Uncharacterized protein. (405 aa)
Ptgs2.SEGF-like domain-containing protein. (726 aa)
Atf4.SBZIP domain-containing protein. (342 aa)
ddr2Uncharacterized protein. (873 aa)
ak4GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (231 aa)
Fndc1.LUncharacterized protein. (1925 aa)
kcnk2Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (412 aa)
Epas1.LUncharacterized protein. (862 aa)
Egln1.SUncharacterized protein. (454 aa)
fndc1Uncharacterized protein. (1944 aa)
epas1Uncharacterized protein. (859 aa)
A0A1L8G198Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (370 aa)
Ndrg1.LUncharacterized protein. (380 aa)
A0A1L8FYS5GATA-type domain-containing protein. (466 aa)
A0A1L8FXP7BH4_2 domain-containing protein. (300 aa)
Aqp1.LUncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (274 aa)
ndrg1Uncharacterized protein. (396 aa)
Myc.SMyc_N domain-containing protein. (176 aa)
A0A1L8FTT4BHLH domain-containing protein. (191 aa)
gata6Uncharacterized protein. (502 aa)
Bcl2.SBH4_2 domain-containing protein. (253 aa)
Aqp1.SUncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (274 aa)
hyou1Uncharacterized protein. (985 aa)
A0A1L8FKW5Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2533 aa)
nfe2l2MGC53355 protein. (591 aa)
Sirt1.LDeacetylase sirtuin-type domain-containing protein. (722 aa)
bnip3Uncharacterized protein. (196 aa)
Ado.LUncharacterized protein. (264 aa)
Sirt2.SNAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (402 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (722 aa)
stox1Stork_head domain-containing protein. (977 aa)
adoUncharacterized protein. (250 aa)
nop53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (452 aa)
egln2-2Fe2OG dioxygenase domain-containing protein. (454 aa)
aifm1Uncharacterized protein. (637 aa)
tsc1-2Uncharacterized protein. (1102 aa)
Suv39h1.LHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (432 aa)
Egln3.SFe2OG dioxygenase domain-containing protein. (252 aa)
suv39h1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (421 aa)
egln2Fe2OG dioxygenase domain-containing protein. (415 aa)
tsc1Uncharacterized protein. (1104 aa)
ddr2lUncharacterized protein. (879 aa)
Hif-1aUncharacterized protein. (800 aa)
A0A1L8EY00Eukaryotic elongation factor 2 kinase. (718 aa)
npepps-2Aminopeptidase. (953 aa)
A0A1L8EQI2Eukaryotic elongation factor 2 kinase. (741 aa)
Nfe2l2.SBZIP domain-containing protein; Belongs to the bZIP family. (590 aa)
npeppsAminopeptidase. (875 aa)
A0A1L8EKE6F5/8 type C domain-containing protein. (105 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
hif1anMGC84481 protein. (352 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.