(29 nodes) Positive regulation of multicellular organism growth network (Xenopus laevis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pex5	TPR_REGION domain-containing protein. (619 aa)
	A0A1L8EX51	Uncharacterized protein. (327 aa)
	A0A1L8F0K0	G_PROTEIN_RECEP_F1_2 domain-containing protein. (607 aa)
	A0A1L8F7V6	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (760 aa)
	Gpam.S	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (784 aa)
	Drd2.S	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (437 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (818 aa)
	Drd2.L	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (438 aa)
	slc6a3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
	Bcl2.S	BH4_2 domain-containing protein. (253 aa)
	A0A1L8FXP7	BH4_2 domain-containing protein. (300 aa)
	Ghsr.S	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (348 aa)
	A0A1L8G4C9	Uncharacterized protein. (623 aa)
	mkks	Uncharacterized protein. (572 aa)
	Ghsr.L	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (348 aa)
	A0A1L8GAZ8	Uncharacterized protein. (624 aa)
	igf2	IlGF domain-containing protein. (217 aa)
	Bbs2.S	Uncharacterized protein. (761 aa)
	igf2-2	IlGF domain-containing protein. (217 aa)
	A0A1L8GTC8	TPR_REGION domain-containing protein. (516 aa)
	Smo.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
	Smo.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
	A0A1L8HRR4	Nipped-B protein. (1728 aa)
	nipbl	Nipped-B protein. (2844 aa)
	ppib	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	ezr	MGC82058 protein. (582 aa)
	ppib-2	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	creb1	Creb1-prov protein. (324 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EX51	A0A1L8FXP7	A0A1L8EX51	A0A1L8FXP7	Uncharacterized protein.	BH4_2 domain-containing protein.	0.411
A0A1L8EX51	Bcl2.S	A0A1L8EX51	A0A1L8FSA4	Uncharacterized protein.	BH4_2 domain-containing protein.	0.411
A0A1L8F0K0	TSHR	A0A1L8F0K0	A0A1L8F9E1	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.900
A0A1L8F7V6	Ghsr.L	A0A1L8F7V6	A0A1L8GAI7	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.903
A0A1L8F7V6	Ghsr.S	A0A1L8F7V6	A0A1L8G472	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.903
A0A1L8FXP7	A0A1L8EX51	A0A1L8FXP7	A0A1L8EX51	BH4_2 domain-containing protein.	Uncharacterized protein.	0.411
A0A1L8FXP7	Bcl2.S	A0A1L8FXP7	A0A1L8FSA4	BH4_2 domain-containing protein.	BH4_2 domain-containing protein.	0.900
A0A1L8FXP7	creb1	A0A1L8FXP7	Q8AVY5	BH4_2 domain-containing protein.	Creb1-prov protein.	0.411
A0A1L8G4C9	ezr	A0A1L8G4C9	Q6AX84	Uncharacterized protein.	MGC82058 protein.	0.678
A0A1L8GAZ8	ezr	A0A1L8GAZ8	Q6AX84	Uncharacterized protein.	MGC82058 protein.	0.678
A0A1L8GTC8	Bbs2.S	A0A1L8GTC8	A0A1L8GEJ7	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.994
A0A1L8GTC8	Smo.L	A0A1L8GTC8	A0A1L8GZN4	TPR_REGION domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.717
A0A1L8GTC8	Smo.S	A0A1L8GTC8	A0A1L8GTP2	TPR_REGION domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.717
Bbs2.S	A0A1L8GTC8	A0A1L8GEJ7	A0A1L8GTC8	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.994
Bbs2.S	Smo.L	A0A1L8GEJ7	A0A1L8GZN4	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.728
Bbs2.S	Smo.S	A0A1L8GEJ7	A0A1L8GTP2	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.728
Bbs2.S	mkks	A0A1L8GEJ7	A0A1L8G7D7	Uncharacterized protein.	Uncharacterized protein.	0.557
Bcl2.S	A0A1L8EX51	A0A1L8FSA4	A0A1L8EX51	BH4_2 domain-containing protein.	Uncharacterized protein.	0.411
Bcl2.S	A0A1L8FXP7	A0A1L8FSA4	A0A1L8FXP7	BH4_2 domain-containing protein.	BH4_2 domain-containing protein.	0.900
Bcl2.S	creb1	A0A1L8FSA4	Q8AVY5	BH4_2 domain-containing protein.	Creb1-prov protein.	0.738