31 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pkd1	Uncharacterized protein. (4353 aa)
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	A0A1L8EKF4	FZ domain-containing protein. (134 aa)
	A0A1L8EPZ4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
	A0A1L8ES96	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (554 aa)
	A0A1L8EUA6	Uncharacterized protein. (3827 aa)
	A0A1L8EUA7	PKD domain-containing protein. (501 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	A0A1L8EX74	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	ryk	Uncharacterized protein. (596 aa)
	A0A1L8GFH0	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (946 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	A0A1L8GM33	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (944 aa)
	A0A1L8GQT6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	fzd9	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	A0A1L8HD44	FZ domain-containing protein. (183 aa)
	fzd9-2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
	A0A1L8HJF4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (456 aa)
	fzd10	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
	fzd10a	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
	fz3	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	A0A1L8FQX7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
	Fzd6.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	fzd6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
	A0A1L8G548	Uncharacterized protein. (465 aa)
	fzd3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EPZ4	A0A1L8GFH0	A0A1L8EPZ4	A0A1L8GFH0	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.792
A0A1L8EPZ4	A0A1L8GM33	A0A1L8EPZ4	A0A1L8GM33	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.792
A0A1L8EPZ4	A0A1L8GQT6	A0A1L8EPZ4	A0A1L8GQT6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.889
A0A1L8EPZ4	Fzd6.S	A0A1L8EPZ4	A0A1L8FTP5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.402
A0A1L8EPZ4	Lrp5.L	A0A1L8EPZ4	A0A1L8GJX4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.887
A0A1L8EPZ4	fzd6	A0A1L8EPZ4	A0A1L8FZR1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.402
A0A1L8EPZ4	ryk	A0A1L8EPZ4	A0A1L8GB75	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.702
A0A1L8ES96	A0A1L8GFH0	A0A1L8ES96	A0A1L8GFH0	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.792
A0A1L8ES96	A0A1L8GM33	A0A1L8ES96	A0A1L8GM33	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.792
A0A1L8ES96	A0A1L8GQT6	A0A1L8ES96	A0A1L8GQT6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.889
A0A1L8ES96	Fzd6.S	A0A1L8ES96	A0A1L8FTP5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.411
A0A1L8ES96	Lrp5.L	A0A1L8ES96	A0A1L8GJX4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.918
A0A1L8ES96	fzd6	A0A1L8ES96	A0A1L8FZR1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.412
A0A1L8ES96	ryk	A0A1L8ES96	A0A1L8GB75	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.766
A0A1L8EX74	A0A1L8GFH0	A0A1L8EX74	A0A1L8GFH0	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.802
A0A1L8EX74	A0A1L8GM33	A0A1L8EX74	A0A1L8GM33	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.802
A0A1L8EX74	A0A1L8GQT6	A0A1L8EX74	A0A1L8GQT6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.938
A0A1L8EX74	Fzd6.S	A0A1L8EX74	A0A1L8FTP5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.406
A0A1L8EX74	Lrp5.L	A0A1L8EX74	A0A1L8GJX4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.911
A0A1L8EX74	fzd6	A0A1L8EX74	A0A1L8FZR1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.406