104 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Acvr1c.S	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (492 aa)
	Cyct.L	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (136 aa)
	casp10	Uncharacterized protein; Belongs to the peptidase C14A family. (520 aa)
	Cflar.S	Uncharacterized protein; Belongs to the peptidase C14A family. (493 aa)
	gper1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	tfap4	BHLH domain-containing protein. (333 aa)
	A0A1L8EVX2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (492 aa)
	cyct	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	Casp8.L	Uncharacterized protein; Belongs to the peptidase C14A family. (500 aa)
	cflar	Uncharacterized protein; Belongs to the peptidase C14A family. (502 aa)
	gper1-2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	tfap4-2	BHLH domain-containing protein. (333 aa)
	card9	CARD domain-containing protein. (527 aa)
	rack1	WD_REPEATS_REGION domain-containing protein. (276 aa)
	tnf	TNF_2 domain-containing protein. (227 aa)
	card9-2	CARD domain-containing protein. (527 aa)
	A0A1L8F6E0	WD_REPEATS_REGION domain-containing protein. (165 aa)
	aifm1	Uncharacterized protein. (637 aa)
	A0A1L8FCP4	NACHT domain-containing protein. (882 aa)
	A0A1L8FCQ3	NACHT domain-containing protein. (883 aa)
	A0A1L8FCS0	NACHT domain-containing protein. (883 aa)
	A0A1L8FDU4	Uncharacterized protein; Belongs to the peptidase C14A family. (423 aa)
	A0A1L8FE31	Uncharacterized protein. (332 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (722 aa)
	Bax.L	Uncharacterized protein. (221 aa)
	Casp9.S	Uncharacterized protein; Belongs to the peptidase C14A family. (399 aa)
	Casp2.L	Uncharacterized protein; Belongs to the peptidase C14A family. (423 aa)
	A0A1L8FII3	Uncharacterized protein. (314 aa)
	Sirt1.L	Deacetylase sirtuin-type domain-containing protein. (722 aa)
	mul1	RING-type domain-containing protein. (353 aa)
	cycs	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	A0A1L8FT36	MYT1 domain-containing protein. (997 aa)
	A0A1L8FTT4	BHLH domain-containing protein. (191 aa)
	Myc.S	Myc_N domain-containing protein. (176 aa)
	A0A1L8FW52	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	dap	Uncharacterized protein. (107 aa)
	St18.L	MYT1 domain-containing protein. (983 aa)
	bcl2l11	Uncharacterized protein. (194 aa)
	Pdcd2.S	MYND-type domain-containing protein. (369 aa)
	A0A1L8G343	Uncharacterized protein. (1788 aa)
	A0A1L8G3I0	RING-type domain-containing protein. (344 aa)
	bok	Uncharacterized protein. (214 aa)
	sox7	Uncharacterized protein. (363 aa)
	bcl2l11-2	Uncharacterized protein. (194 aa)
	nlrc4	Uncharacterized protein. (1015 aa)
	A0A1L8G9R4	Uncharacterized protein. (1695 aa)
	bok-2	Uncharacterized protein. (214 aa)
	sox7-2	Uncharacterized protein. (362 aa)
	A0A1L8GF46	Uncharacterized protein. (343 aa)
	faslg	TNF_2 domain-containing protein. (246 aa)
	pidd1	Uncharacterized protein. (909 aa)
	A0A1L8GJQ1	Uncharacterized protein. (151 aa)
	pdcd5	Uncharacterized protein. (125 aa)
	A0A1L8GLM2	Uncharacterized protein. (375 aa)
	Faslg.L	TNF_2 domain-containing protein. (248 aa)
	Arl6ip5.L	PRA1 family protein. (188 aa)
	Bid.S	Uncharacterized protein. (238 aa)
	nkx3-1	Homeobox domain-containing protein. (213 aa)
	uaca	ANK_REP_REGION domain-containing protein. (1391 aa)
	A0A1L8GTG8	Uncharacterized protein. (641 aa)
	Gramd4.S	GRAM domain-containing protein. (603 aa)
	prr7	Uncharacterized protein. (262 aa)
	prr7-2	Uncharacterized protein. (258 aa)
	A0A1L8GY03	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1205 aa)
	Gramd4.L	GRAM domain-containing protein. (651 aa)
	A0A1L8GZW5	Uncharacterized protein. (633 aa)
	uaca-2	ANK_REP_REGION domain-containing protein. (1390 aa)
	Nkx3-1.L	Homeobox domain-containing protein. (213 aa)
	A0A1L8H618	Uncharacterized protein. (935 aa)
	laptm5	Uncharacterized protein. (268 aa)
	A0A1L8H8B2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1033 aa)
	Ift57.S	Ig-like domain-containing protein. (411 aa)
	A0A1L8HDW9	Uncharacterized protein. (935 aa)
	laptm5-2	Uncharacterized protein. (269 aa)
	p2rx1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (412 aa)
	A0A1L8HHR6	Uncharacterized protein. (174 aa)
	rps3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (246 aa)
	htra2	PDZ domain-containing protein. (407 aa)
	eif2ak3	Protein kinase domain-containing protein. (1091 aa)
	Rest.S	Uncharacterized protein. (1337 aa)
	Syk.S	Tyrosine-protein kinase. (632 aa)
	A0A1L8HQ06	Uncharacterized protein. (231 aa)
	Hip1r.S	Uncharacterized protein. (1064 aa)
	diablo	Uncharacterized protein. (258 aa)
	malt1	Uncharacterized protein. (800 aa)
	A0A1L8HT45	Protein kinase domain-containing protein. (1127 aa)
	Rest.L	Uncharacterized protein. (1421 aa)
	acer2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	syk	Tyrosine-protein kinase. (605 aa)
	Hip1r.L	Uncharacterized protein. (1066 aa)
	Diablo.L	Uncharacterized protein. (258 aa)
	malt1-2	Uncharacterized protein. (796 aa)
	A0A310TNK6	Uncharacterized protein. (708 aa)
	tnf-2	Tumor necrosis factor alpha. (225 aa)
	acer2-2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	arl6ip5	PRA1 family protein. (188 aa)
	atp2a3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1033 aa)
	pdcd5-2	LOC495300 protein. (126 aa)
	LOC494858	LOC494858 protein. (231 aa)
	cradd.2	MGC78788 protein. (197 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
	casp10-2	MGC68465 protein; Belongs to the peptidase C14A family. (512 aa)
	rpls3-b	Rpls3-b protein; Belongs to the universal ribosomal protein uS3 family. (246 aa)
	rack1-2	Gnb2l1-prov protein. (317 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EVX2	Acvr1c.S	A0A1L8EVX2	A0A1L8EP06	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.900
A0A1L8F6E0	rpls3-b	A0A1L8F6E0	Q7ZYT3	WD_REPEATS_REGION domain-containing protein.	Rpls3-b protein; Belongs to the universal ribosomal protein uS3 family.	0.951
A0A1L8F6E0	rps3	A0A1L8F6E0	A0A1L8HJY0	WD_REPEATS_REGION domain-containing protein.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.951
A0A1L8FCP4	nlrc4	A0A1L8FCP4	A0A1L8G7S6	NACHT domain-containing protein.	Uncharacterized protein.	0.495
A0A1L8FCQ3	nlrc4	A0A1L8FCQ3	A0A1L8G7S6	NACHT domain-containing protein.	Uncharacterized protein.	0.495
A0A1L8FCS0	nlrc4	A0A1L8FCS0	A0A1L8G7S6	NACHT domain-containing protein.	Uncharacterized protein.	0.495
A0A1L8FDU4	A0A1L8FE31	A0A1L8FDU4	A0A1L8FE31	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.496
A0A1L8FDU4	A0A1L8FII3	A0A1L8FDU4	A0A1L8FII3	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.496
A0A1L8FDU4	A0A1L8FW52	A0A1L8FDU4	A0A1L8FW52	Uncharacterized protein; Belongs to the peptidase C14A family.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.882
A0A1L8FDU4	A0A1L8GY03	A0A1L8FDU4	A0A1L8GY03	Uncharacterized protein; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.913
A0A1L8FDU4	Bid.S	A0A1L8FDU4	A0A1L8GQT1	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.964
A0A1L8FDU4	Casp2.L	A0A1L8FDU4	A0A1L8FIC4	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.901
A0A1L8FDU4	Casp8.L	A0A1L8FDU4	A0A1L8EWT3	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.660
A0A1L8FDU4	Casp9.S	A0A1L8FDU4	A0A1L8FHM1	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.725
A0A1L8FDU4	Cyct.L	A0A1L8FDU4	A0A1L8EP92	Uncharacterized protein; Belongs to the peptidase C14A family.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.881
A0A1L8FDU4	Diablo.L	A0A1L8FDU4	A0A1L8I1L4	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.638
A0A1L8FDU4	Faslg.L	A0A1L8FDU4	A0A1L8GN18	Uncharacterized protein; Belongs to the peptidase C14A family.	TNF_2 domain-containing protein.	0.566
A0A1L8FDU4	casp10	A0A1L8FDU4	A0A1L8EPS7	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.614
A0A1L8FDU4	casp10-2	A0A1L8FDU4	Q6PAD9	Uncharacterized protein; Belongs to the peptidase C14A family.	MGC68465 protein; Belongs to the peptidase C14A family.	0.614
A0A1L8FDU4	cradd.2	A0A1L8FDU4	Q6GR68	Uncharacterized protein; Belongs to the peptidase C14A family.	MGC78788 protein.	0.996