61 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Mtmr4.L	Uncharacterized protein. (1078 aa)
	inpp5k	IPPc domain-containing protein. (476 aa)
	inpp5b	Rho-GAP domain-containing protein. (754 aa)
	A0A1L8HFF2	Uncharacterized protein. (384 aa)
	Tpte2.L	Uncharacterized protein. (509 aa)
	A0A1L8HJ15	IPPc domain-containing protein. (514 aa)
	mtmr6	Myotubularin phosphatase domain-containing protein. (622 aa)
	mtmr2-2	Uncharacterized protein. (570 aa)
	inppl1	Uncharacterized protein. (1268 aa)
	A0A1L8HLB0	Uncharacterized protein. (550 aa)
	pip4p1	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (282 aa)
	A0A1L8HPX7	IPPc domain-containing protein. (772 aa)
	mtmr3	Uncharacterized protein. (1209 aa)
	A0A1L8HPZ2	Uncharacterized protein. (1011 aa)
	mtmr7	Uncharacterized protein. (656 aa)
	pip4p1-2	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (281 aa)
	Mtmr3	Uncharacterized protein. (1224 aa)
	inpp5j	IPPc domain-containing protein. (784 aa)
	mtmr12	Myotubularin phosphatase domain-containing protein. (748 aa)
	A0A310TPZ2	Uncharacterized protein. (154 aa)
	pten	Phosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
	LOC100101282	LOC100101282 protein. (557 aa)
	mtmr9-2	LOC496015 protein. (549 aa)
	inpp5a.1-2	MGC83747 protein. (412 aa)
	synj1	SAC domain-containing protein. (1544 aa)
	A0A1L8F0Y7	IPPc domain-containing protein. (478 aa)
	A0A1L8F1A1	Uncharacterized protein. (1553 aa)
	ocrl	Rho-GAP domain-containing protein. (910 aa)
	mtm1	Uncharacterized protein. (602 aa)
	A0A1L8F2X3	Myotubularin phosphatase domain-containing protein. (690 aa)
	Mtmr11.S	Myotubularin phosphatase domain-containing protein. (696 aa)
	A0A1L8F610	IPPc domain-containing protein. (628 aa)
	A0A1L8F6Y5	SH2 domain-containing protein. (866 aa)
	A0A1L8F773	Myotubularin phosphatase domain-containing protein. (642 aa)
	ocrl-2	Rho-GAP domain-containing protein. (911 aa)
	mtm1-2	Uncharacterized protein. (602 aa)
	A0A1L8F7L2	Myotubularin phosphatase domain-containing protein. (667 aa)
	Mtmr11.L	Myotubularin phosphatase domain-containing protein. (846 aa)
	inpp5f	Uncharacterized protein. (1108 aa)
	Pten.L	Phosphatase and tensin homolog L homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
	inpp5a.1	IPPc domain-containing protein. (412 aa)
	pip4p2	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (327 aa)
	sacm1l	SAC domain-containing protein. (586 aa)
	A0A1L8FY54	IPPc domain-containing protein. (500 aa)
	A0A1L8FY65	IPPc domain-containing protein. (235 aa)
	Tmem55a.L	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (292 aa)
	inpp5d	SH2 domain-containing protein. (1099 aa)
	mtmr9	Myotubularin phosphatase domain-containing protein. (549 aa)
	A0A1L8G8G7	Uncharacterized protein. (1395 aa)
	A0A1L8G9D7	SAC domain-containing protein. (907 aa)
	Inpp5d.L	SH2 domain-containing protein. (1111 aa)
	Mtmr10.S	Myotubularin phosphatase domain-containing protein. (839 aa)
	mtmr10	Myotubularin phosphatase domain-containing protein. (764 aa)
	A0A1L8H274	IPPc domain-containing protein. (385 aa)
	mtmr4	Uncharacterized protein. (1076 aa)
	A0A1L8HAD6	Uncharacterized protein. (509 aa)
	A0A1L8HAJ7	IPPc domain-containing protein. (427 aa)
	A0A1L8HAL8	Uncharacterized protein. (291 aa)
	A0A1L8HAM5	IPPc domain-containing protein. (423 aa)
	mtmr2	Uncharacterized protein. (570 aa)
	Synj1.L	Uncharacterized protein. (2634 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F2X3	A0A1L8G9D7	A0A1L8F2X3	A0A1L8G9D7	Myotubularin phosphatase domain-containing protein.	SAC domain-containing protein.	0.936
A0A1L8F2X3	LOC100101282	A0A1L8F2X3	A2VD72	Myotubularin phosphatase domain-containing protein.	LOC100101282 protein.	0.408
A0A1L8F2X3	Mtmr10.S	A0A1L8F2X3	A0A1L8GT42	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.551
A0A1L8F2X3	Tmem55a.L	A0A1L8F2X3	A0A1L8FZG0	Myotubularin phosphatase domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.658
A0A1L8F2X3	inpp5f	A0A1L8F2X3	A0A1L8FIA4	Myotubularin phosphatase domain-containing protein.	Uncharacterized protein.	0.659
A0A1L8F2X3	mtmr10	A0A1L8F2X3	A0A1L8H0E1	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.551
A0A1L8F2X3	mtmr12	A0A1L8F2X3	A0A1L8I2N1	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.549
A0A1L8F2X3	pip4p1	A0A1L8F2X3	A0A1L8HPT9	Myotubularin phosphatase domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.658
A0A1L8F2X3	pip4p1-2	A0A1L8F2X3	A0A1L8HZK6	Myotubularin phosphatase domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.658
A0A1L8F2X3	pip4p2	A0A1L8F2X3	A0A1L8FTE1	Myotubularin phosphatase domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.658
A0A1L8F2X3	sacm1l	A0A1L8F2X3	A0A1L8FX21	Myotubularin phosphatase domain-containing protein.	SAC domain-containing protein.	0.720
A0A1L8F610	Pten.L	A0A1L8F610	A0A1L8FIH0	IPPc domain-containing protein.	Phosphatase and tensin homolog L homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.913
A0A1L8F610	Tmem55a.L	A0A1L8F610	A0A1L8FZG0	IPPc domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.657
A0A1L8F610	inpp5f	A0A1L8F610	A0A1L8FIA4	IPPc domain-containing protein.	Uncharacterized protein.	0.902
A0A1L8F610	pip4p1	A0A1L8F610	A0A1L8HPT9	IPPc domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.650
A0A1L8F610	pip4p1-2	A0A1L8F610	A0A1L8HZK6	IPPc domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.650
A0A1L8F610	pip4p2	A0A1L8F610	A0A1L8FTE1	IPPc domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.657
A0A1L8F610	pten	A0A1L8F610	A1L2J3	IPPc domain-containing protein.	Phosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.913
A0A1L8F610	sacm1l	A0A1L8F610	A0A1L8FX21	IPPc domain-containing protein.	SAC domain-containing protein.	0.916
A0A1L8F6Y5	A0A1L8G8G7	A0A1L8F6Y5	A0A1L8G8G7	SH2 domain-containing protein.	Uncharacterized protein.	0.739