(53 nodes) Positive regulation of viral process network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lgals1.1	Galectin. (134 aa)
	A0A1L8FRI6	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1695 aa)
	top2b	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1696 aa)
	Tbc1d20.2.L	Rab-GAP TBC domain-containing protein. (388 aa)
	A0A1L8G9F4	Autophagy protein 5; Involved in autophagic vesicle formation. (334 aa)
	ddb1	CPSF_A domain-containing protein. (1140 aa)
	A0A1L8GE79	Uncharacterized protein. (394 aa)
	A0A1L8GG25	Uncharacterized protein. (1252 aa)
	Lgals1.S	Galectin. (134 aa)
	A0A1L8GI41	Uncharacterized protein. (351 aa)
	pde12	Endo/exonuclease/phosphatase domain-containing protein. (565 aa)
	A0A1L8GMQ0	Uncharacterized protein. (1244 aa)
	A0A1L8GNW6	Galectin. (139 aa)
	lgals1.2	Galectin. (135 aa)
	larp1	HTH La-type RNA-binding domain-containing protein. (1015 aa)
	Cd74.S	Thyroglobulin type-1 domain-containing protein. (302 aa)
	tmprss4	Uncharacterized protein; Belongs to the peptidase S1 family. (618 aa)
	A0A1L8FIL9	Ig-like domain-containing protein. (491 aa)
	Tmprss4.S	Uncharacterized protein; Belongs to the peptidase S1 family. (588 aa)
	A0A1L8FDY2	Ig-like domain-containing protein. (467 aa)
	A0A1L8FD24	Uncharacterized protein. (1045 aa)
	axl-2	Uncharacterized protein. (896 aa)
	tmem250-2	Uncharacterized protein. (139 aa)
	adar	Uncharacterized protein. (1291 aa)
	axl	Uncharacterized protein. (890 aa)
	tmem250	Uncharacterized protein. (139 aa)
	Tyro3.S	Uncharacterized protein. (832 aa)
	Stau1.L	Uncharacterized protein. (689 aa)
	stau1	Uncharacterized protein. (707 aa)
	A0A1L8EJY7	Uncharacterized protein. (68 aa)
	tbc1d20.1	Rab-GAP TBC domain-containing protein. (387 aa)
	A0A1L8GW07	Uncharacterized protein. (414 aa)
	Tmem39a.S	Uncharacterized protein. (488 aa)
	tmem39b	Uncharacterized protein. (477 aa)
	rsf1	Uncharacterized protein. (1446 aa)
	A0A1L8HC61	Uncharacterized protein. (447 aa)
	tmem39b-2	Uncharacterized protein. (483 aa)
	Ppie.L	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (321 aa)
	cnot7	Uncharacterized protein. (285 aa)
	A0A1L8HLM5	PPIase cyclophilin-type domain-containing protein. (341 aa)
	A0A1L8HUD3	Uncharacterized protein. (370 aa)
	A0A310U122	A to I editase domain-containing protein. (118 aa)
	atg12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (132 aa)
	lgalsvb-a	Galectin. (135 aa)
	MGC68472	MGC68472 protein. (287 aa)
	larp1-2	MGC98945 protein. (1021 aa)
	ppara	Ppara protein. (474 aa)
	top2a	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1579 aa)
	fkbp6	Peptidylprolyl isomerase. (304 aa)
	cd74	MGC68635 protein. (293 aa)
	vps37b	Flj12750-prov protein. (281 aa)
	tbc1d20.1-2	MGC52691 protein. (412 aa)
	lgals1.3	Galectin. (135 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FDY2	A0A1L8FIL9	A0A1L8FDY2	A0A1L8FIL9	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.900
A0A1L8FDY2	A0A1L8G9F4	A0A1L8FDY2	A0A1L8G9F4	Ig-like domain-containing protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.561
A0A1L8FDY2	A0A1L8GW07	A0A1L8FDY2	A0A1L8GW07	Ig-like domain-containing protein.	Uncharacterized protein.	0.476
A0A1L8FDY2	Cd74.S	A0A1L8FDY2	A0A1L8GRC3	Ig-like domain-containing protein.	Thyroglobulin type-1 domain-containing protein.	0.551
A0A1L8FDY2	cd74	A0A1L8FDY2	Q6PB08	Ig-like domain-containing protein.	MGC68635 protein.	0.551
A0A1L8FDY2	ddb1	A0A1L8FDY2	A0A1L8GD94	Ig-like domain-containing protein.	CPSF_A domain-containing protein.	0.478
A0A1L8FDY2	ppara	A0A1L8FDY2	Q6AXA9	Ig-like domain-containing protein.	Ppara protein.	0.476
A0A1L8FIL9	A0A1L8FDY2	A0A1L8FIL9	A0A1L8FDY2	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.900
A0A1L8FIL9	A0A1L8G9F4	A0A1L8FIL9	A0A1L8G9F4	Ig-like domain-containing protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.561
A0A1L8FIL9	A0A1L8GW07	A0A1L8FIL9	A0A1L8GW07	Ig-like domain-containing protein.	Uncharacterized protein.	0.476
A0A1L8FIL9	Cd74.S	A0A1L8FIL9	A0A1L8GRC3	Ig-like domain-containing protein.	Thyroglobulin type-1 domain-containing protein.	0.551
A0A1L8FIL9	cd74	A0A1L8FIL9	Q6PB08	Ig-like domain-containing protein.	MGC68635 protein.	0.551
A0A1L8FIL9	ddb1	A0A1L8FIL9	A0A1L8GD94	Ig-like domain-containing protein.	CPSF_A domain-containing protein.	0.478
A0A1L8FIL9	ppara	A0A1L8FIL9	Q6AXA9	Ig-like domain-containing protein.	Ppara protein.	0.476
A0A1L8G9F4	A0A1L8FDY2	A0A1L8G9F4	A0A1L8FDY2	Autophagy protein 5; Involved in autophagic vesicle formation.	Ig-like domain-containing protein.	0.561
A0A1L8G9F4	A0A1L8FIL9	A0A1L8G9F4	A0A1L8FIL9	Autophagy protein 5; Involved in autophagic vesicle formation.	Ig-like domain-containing protein.	0.561
A0A1L8G9F4	atg12	A0A1L8G9F4	A8E622	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.997
A0A1L8GE79	MGC68472	A0A1L8GE79	Q3KQB9	Uncharacterized protein.	MGC68472 protein.	0.979
A0A1L8GE79	vps37b	A0A1L8GE79	Q8AVK6	Uncharacterized protein.	Flj12750-prov protein.	0.979
A0A1L8GG25	adar	A0A1L8GG25	A0A1L8F4Z0	Uncharacterized protein.	Uncharacterized protein.	0.747