STRINGSTRING
A0A1L8EK31 A0A1L8EK31 A0A1L8EKQ1 A0A1L8EKQ1 A0A1L8ELA2 A0A1L8ELA2 Ctsz.S Ctsz.S A0A1L8EM96 A0A1L8EM96 A0A1L8ENK0 A0A1L8ENK0 A0A1L8ENZ6 A0A1L8ENZ6 A0A1L8EP11 A0A1L8EP11 gbx2.2 gbx2.2 med1l med1l wnt9b.2 wnt9b.2 A0A1L8ESZ5 A0A1L8ESZ5 A0A1L8EUA6 A0A1L8EUA6 A0A1L8EUA7 A0A1L8EUA7 gna13 gna13 Tgfbr2.2.L Tgfbr2.2.L wnt6 wnt6 Acvr1.L Acvr1.L Gbx2.2.L Gbx2.2.L pkd1 pkd1 A0A1L8F1K8 A0A1L8F1K8 ddr1 ddr1 tgfb1 tgfb1 nrarp nrarp tgfb1-2 tgfb1-2 dll4 dll4 A0A1L8FDB0 A0A1L8FDB0 A0A1L8FEK1 A0A1L8FEK1 A0A1L8FEN9 A0A1L8FEN9 G50 G50 btrc btrc Epha2.L Epha2.L hoxa5 hoxa5 Tgfbr2.S Tgfbr2.S gli3 gli3 Bcl2.S Bcl2.S A0A1L8FST0 A0A1L8FST0 Rdh10.S Rdh10.S hoxa5-2 hoxa5-2 tgfbr2 tgfbr2 gli3-2 gli3-2 Med1.L Med1.L A0A1L8FXP7 A0A1L8FXP7 A0A1L8FYP3 A0A1L8FYP3 srf srf gzf1 gzf1 Gdf7.S Gdf7.S gzf1-2 gzf1-2 srf-2 srf-2 ppp3r1 ppp3r1 tcf21 tcf21 gdf7 gdf7 Greb1.L Greb1.L A0A1L8GCB2 A0A1L8GCB2 A0A1L8GDD9 A0A1L8GDD9 A0A1L8GFS0 A0A1L8GFS0 dag1 dag1 plxnd1 plxnd1 A0A1L8GJ35 A0A1L8GJ35 Lrp5.L Lrp5.L A0A1L8GM27 A0A1L8GM27 dag1-2 dag1-2 plxnd1-2 plxnd1-2 nkx3-1 nkx3-1 sema3e sema3e Met.S Met.S fgf1 fgf1 fgf1-2 fgf1-2 Met.L Met.L sema3e-2 sema3e-2 Nkx3-1.L Nkx3-1.L Kdm5b.S Kdm5b.S A0A1L8H804 A0A1L8H804 A0A1L8H9R2 A0A1L8H9R2 wnt1 wnt1 Vdr.L Vdr.L A0A1L8HBK8 A0A1L8HBK8 A0A1L8HBL4 A0A1L8HBL4 A0A1L8HEI9 A0A1L8HEI9 Wnt1.L Wnt1.L A0A1L8HHZ4 A0A1L8HHZ4 vdr vdr A0A1L8HJM7 A0A1L8HJM7 Slit2.S Slit2.S kdr kdr hhip hhip lef1 lef1 areg areg tmem59l tmem59l A0A1L8HPJ2 A0A1L8HPJ2 nfatc4 nfatc4 Gdnf.S Gdnf.S A0A1L8HRY9 A0A1L8HRY9 A0A1L8HTQ2 A0A1L8HTQ2 A0A1L8HTZ2 A0A1L8HTZ2 sfrp2 sfrp2 spry1 spry1 areg-2 areg-2 pkd2 pkd2 tmem59l-2 tmem59l-2 ptch1 ptch1 nfatc4-2 nfatc4-2 Gdnf.L Gdnf.L A0A1L8I2V3 A0A1L8I2V3 A0A310UDT2 A0A310UDT2 mks1 mks1 ednra ednra gbx2.1 gbx2.1 wnt6-2 wnt6-2 spry1-2 spry1-2 tbx20 tbx20 tbx3-A tbx3-A Tbx2 Tbx2 edn1 edn1 gna13-2 gna13-2 mmp14 mmp14 ctnnb1 ctnnb1 hhip-2 hhip-2 ctnnbip1-2 ctnnbip1-2 clic4 clic4 clic4-2 clic4-2 ddr1-2 ddr1-2 hnf1b hnf1b ppp3r1-2 ppp3r1-2 hnf1b-2 hnf1b-2 ctnnb1-2 ctnnb1-2 sfrp2-2 sfrp2-2 ednra-2 ednra-2 fgf8 fgf8 gbx2.1-2 gbx2.1-2 lef1-2 lef1-2 ptch1-2 ptch1-2 ctnnbip1-3 ctnnbip1-3 tbx3 tbx3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1L8EK31Uncharacterized protein. (76 aa)
A0A1L8EKQ1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa)
A0A1L8ELA2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
Ctsz.SPept_C1 domain-containing protein; Belongs to the peptidase C1 family. (319 aa)
A0A1L8EM96ETS domain-containing protein. (363 aa)
A0A1L8ENK0Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
A0A1L8ENZ6SSD domain-containing protein. (946 aa)
A0A1L8EP11Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (484 aa)
gbx2.2Homeobox domain-containing protein. (340 aa)
med1lMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa)
wnt9b.2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
A0A1L8ESZ5Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (302 aa)
A0A1L8EUA6Uncharacterized protein. (3827 aa)
A0A1L8EUA7PKD domain-containing protein. (501 aa)
gna13Uncharacterized protein. (377 aa)
Tgfbr2.2.LSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Acvr1.LReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (624 aa)
Gbx2.2.LHomeobox domain-containing protein. (340 aa)
pkd1Uncharacterized protein. (4353 aa)
A0A1L8F1K8Uncharacterized protein. (572 aa)
ddr1Uncharacterized protein. (947 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
nrarpANK_REP_REGION domain-containing protein. (114 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (675 aa)
A0A1L8FDB0Mothers against decapentaplegic homolog. (514 aa)
A0A1L8FEK1Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (199 aa)
A0A1L8FEN9Uncharacterized protein. (470 aa)
G50Uncharacterized protein. (980 aa)
btrcUncharacterized protein. (564 aa)
Epha2.LUncharacterized protein. (948 aa)
hoxa5Homeobox domain-containing protein. (272 aa)
Tgfbr2.SSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (800 aa)
gli3Uncharacterized protein. (1565 aa)
Bcl2.SBH4_2 domain-containing protein. (253 aa)
A0A1L8FST0Uncharacterized protein. (1867 aa)
Rdh10.SUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
hoxa5-2Homeobox domain-containing protein. (273 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (795 aa)
gli3-2Uncharacterized protein. (1568 aa)
Med1.LMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (649 aa)
A0A1L8FXP7BH4_2 domain-containing protein. (300 aa)
A0A1L8FYP3Uncharacterized protein. (1966 aa)
srfMADS-box domain-containing protein. (449 aa)
gzf1Uncharacterized protein. (705 aa)
Gdf7.STGF_BETA_2 domain-containing protein. (413 aa)
gzf1-2Uncharacterized protein. (704 aa)
srf-2MADS-box domain-containing protein. (448 aa)
ppp3r1Uncharacterized protein. (170 aa)
tcf21BHLH domain-containing protein. (179 aa)
gdf7TGF_BETA_2 domain-containing protein. (411 aa)
Greb1.LUncharacterized protein. (1862 aa)
A0A1L8GCB2Uncharacterized protein. (3837 aa)
A0A1L8GDD9Uncharacterized protein. (414 aa)
A0A1L8GFS0Uncharacterized protein. (1115 aa)
dag1Peptidase S72 domain-containing protein. (886 aa)
plxnd1Sema domain-containing protein. (1875 aa)
A0A1L8GJ35Uncharacterized protein. (380 aa)
Lrp5.LUncharacterized protein. (1517 aa)
A0A1L8GM27Uncharacterized protein. (1030 aa)
dag1-2Peptidase S72 domain-containing protein. (886 aa)
plxnd1-2Sema domain-containing protein. (1875 aa)
nkx3-1Homeobox domain-containing protein. (213 aa)
sema3eSema domain-containing protein; Belongs to the semaphorin family. (769 aa)
Met.SUncharacterized protein. (1354 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (156 aa)
fgf1-2Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Met.LUncharacterized protein. (1355 aa)
sema3e-2Sema domain-containing protein; Belongs to the semaphorin family. (276 aa)
Nkx3-1.LHomeobox domain-containing protein. (213 aa)
Kdm5b.SUncharacterized protein. (1585 aa)
A0A1L8H804TBX domain-containing protein. (642 aa)
A0A1L8H9R2Uncharacterized protein. (1288 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
Vdr.LUncharacterized protein. (444 aa)
A0A1L8HBK8Protein kinase domain-containing protein. (116 aa)
A0A1L8HBL4ANK_REP_REGION domain-containing protein. (263 aa)
A0A1L8HEI9Uncharacterized protein. (1518 aa)
Wnt1.LProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
A0A1L8HHZ4Uncharacterized protein. (1214 aa)
vdrUncharacterized protein. (421 aa)
A0A1L8HJM7Uncharacterized protein. (492 aa)
Slit2.SUncharacterized protein. (1530 aa)
kdrUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1326 aa)
hhipEGF-like domain-containing protein. (698 aa)
lef1HMG box domain-containing protein. (372 aa)
aregEGF-like domain-containing protein. (226 aa)
tmem59lUncharacterized protein. (337 aa)
A0A1L8HPJ2ZnMc domain-containing protein. (581 aa)
nfatc4RHD domain-containing protein. (1086 aa)
Gdnf.SGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (227 aa)
A0A1L8HRY9Mothers against decapentaplegic homolog. (549 aa)
A0A1L8HTQ2Uncharacterized protein. (1521 aa)
A0A1L8HTZ2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
sfrp2Uncharacterized protein. (295 aa)
spry1Uncharacterized protein. (342 aa)
areg-2EGF-like domain-containing protein. (228 aa)
pkd2EF-hand domain-containing protein. (947 aa)
tmem59l-2Uncharacterized protein. (335 aa)
ptch1SSD domain-containing protein. (1422 aa)
nfatc4-2RHD domain-containing protein. (1081 aa)
Gdnf.LTGF_BETA_2 domain-containing protein. (332 aa)
A0A1L8I2V3Mothers against decapentaplegic homolog. (510 aa)
A0A310UDT2Uncharacterized protein. (610 aa)
mks1Mks1 protein. (561 aa)
ednraLOC100036912 protein; Belongs to the G-protein coupled receptor 1 family. (415 aa)
gbx2.1Homeobox domain-containing protein. (340 aa)
wnt6-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
spry1-2Sprouty 1. (319 aa)
tbx20T-box 20. (441 aa)
tbx3-ATranscription repression factor Tbx3. (716 aa)
Tbx2T-box transcription factor Tbx2. (688 aa)
edn1LOC100158354 protein. (221 aa)
gna13-2Heterotrimeric guanine nucleotide binding protein subunit alpha-13. (377 aa)
mmp14Membrane type-1 matrix metalloproteinase 14. (575 aa)
ctnnb1Beta-catenin protein. (781 aa)
hhip-2Hedgehog-interacting protein. (696 aa)
ctnnbip1-2Ctnnbip1b protein. (81 aa)
clic4MGC83873 protein. (252 aa)
clic4-2CLIC4 protein. (252 aa)
ddr1-2MGC69083 protein. (945 aa)
hnf1bMGC68543 protein. (561 aa)
ppp3r1-2Protein phospatase 3 regulatory subunit B alpha isoform type 1. (170 aa)
hnf1b-2Tcf2 protein. (561 aa)
ctnnb1-2Ctnnb1-prov protein. (781 aa)
sfrp2-2Sfrp2-prov protein. (298 aa)
ednra-2Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (415 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
gbx2.1-2Homeobox protein GBX-2b. (336 aa)
lef1-2Lymphoid enhancer factor XLEF-1. (372 aa)
ptch1-2Patched-1. (1418 aa)
ctnnbip1-3Beta-catenin-interacting protein. (81 aa)
tbx3Transcription factor Tbx3. (711 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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