STRINGSTRING
adnp adnp Ctsz.S Ctsz.S e2f1 e2f1 wfikkn2 wfikkn2 A0A1L8ENN6 A0A1L8ENN6 A0A1L8ENV4 A0A1L8ENV4 Itga4.S Itga4.S Map2.S Map2.S Dhrs7b.S Dhrs7b.S tfap4 tfap4 adnp-2 adnp-2 A0A1L8ESZ5 A0A1L8ESZ5 A0A1L8ETZ8 A0A1L8ETZ8 A0A1L8EUS7 A0A1L8EUS7 epb41l5 epb41l5 Dnajb2.L Dnajb2.L itga4 itga4 Map2.L Map2.L dhrs7b dhrs7b Ercc4.L Ercc4.L wfikkn1 wfikkn1 tfap4-2 tfap4-2 ttbk2 ttbk2 A0A1L8EZY9 A0A1L8EZY9 Dact1.S Dact1.S A0A1L8F0E5 A0A1L8F0E5 Gnl3l.S Gnl3l.S A0A1L8F397 A0A1L8F397 sympk sympk rack1 rack1 gata1 gata1 gemin2 gemin2 nes nes A0A1L8F6E0 A0A1L8F6E0 A0A1L8F6T4 A0A1L8F6T4 A0A1L8F7X7 A0A1L8F7X7 styx styx dact1 dact1 psen1 psen1 ttbk2-2 ttbk2-2 nes-2 nes-2 pex14 pex14 Park7.S Park7.S Bax.L Bax.L dkk1 dkk1 A0A1L8FJ72 A0A1L8FJ72 wapl wapl Pex14.L Pex14.L sorl1 sorl1 Sri.S Sri.S Rock1.S Rock1.S Efhb.L Efhb.L A0A1L8FX67 A0A1L8FX67 A0A1L8FX70 A0A1L8FX70 Dtnbp1.L Dtnbp1.L arhgap28 arhgap28 Rock1.L Rock1.L ttbk1 ttbk1 pln pln bag2 bag2 adipoq adipoq A0A1L8G5B3 A0A1L8G5B3 ttbk1-2 ttbk1-2 pln-2 pln-2 bag2-2 bag2-2 A0A1L8GE22 A0A1L8GE22 A0A1L8GE55 A0A1L8GE55 A0A1L8GEA7 A0A1L8GEA7 A0A1L8GFZ0 A0A1L8GFZ0 A0A1L8GHK1 A0A1L8GHK1 Myod1.L Myod1.L A0A1L8GI81 A0A1L8GI81 A0A1L8GI97 A0A1L8GI97 A0A1L8GI98 A0A1L8GI98 A0A1L8GIA9 A0A1L8GIA9 A0A1L8GIC3 A0A1L8GIC3 Tfip11.L Tfip11.L FOG FOG Jun.L Jun.L Pcsk9.L Pcsk9.L pdgfb pdgfb A0A1L8GPB5 A0A1L8GPB5 cav3.1 cav3.1 A0A1L8GR35 A0A1L8GR35 Smo.S Smo.S Tdg.S Tdg.S Ddx11.L Ddx11.L lrrk2 lrrk2 Smo.L Smo.L gtf2f1 gtf2f1 A0A1L8H4E2 A0A1L8H4E2 il10 il10 A0A1L8H766 A0A1L8H766 A0A1L8H7W7 A0A1L8H7W7 A0A1L8H8B2 A0A1L8H8B2 ddit3 ddit3 rsf1 rsf1 Znf593.L Znf593.L il10-2 il10-2 kdm1a kdm1a A0A1L8HG24 A0A1L8HG24 mitd1 mitd1 A0A1L8HHR6 A0A1L8HHR6 A0A1L8HJ50 A0A1L8HJ50 A0A1L8HKV2 A0A1L8HKV2 msx1 msx1 A0A1L8HLI5 A0A1L8HLI5 A0A1L8HLQ5 A0A1L8HLQ5 A0A1L8HLQ7 A0A1L8HLQ7 lef1 lef1 Rest.S Rest.S tnks tnks znf462 znf462 Habp4.S Habp4.S nfatc4 nfatc4 A0A1L8HRQ5 A0A1L8HRQ5 Lrpap1.L Lrpap1.L Crmp1.L Crmp1.L hand2 hand2 fbxw7 fbxw7 Rest.L Rest.L A0A1L8HYA8 A0A1L8HYA8 Habp4.L Habp4.L znf462-2 znf462-2 nfatc4-2 nfatc4-2 A0A1L8I2I6 A0A1L8I2I6 Arhgap28.S Arhgap28.S e2f1-2 e2f1-2 LOC496290 LOC496290 sri sri msx1-2 msx1-2 gtpbp4 gtpbp4 nog nog gata1a-A gata1a-A hand1 hand1 dkk1-2 dkk1-2 hmga2 hmga2 pex19 pex19 ilrun ilrun pex19-2 pex19-2 atp2a3 atp2a3 LOC495155 LOC495155 hmga2-2 hmga2-2 pdgfb-2 pdgfb-2 ctnnbip1-2 ctnnbip1-2 pin1 pin1 adipoq-2 adipoq-2 cav1a cav1a park7 park7 cav1 cav1 ddit3-2 ddit3-2 fam192a fam192a rack1-2 rack1-2 Cav-3 Cav-3 lef1-2 lef1-2 ctnnbip1-3 ctnnbip1-3 pin1-2 pin1-2 c-Jun c-Jun Nek2 Nek2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
adnpUncharacterized protein. (1093 aa)
Ctsz.SPept_C1 domain-containing protein; Belongs to the peptidase C1 family. (319 aa)
e2f1E2F_TDP domain-containing protein. (427 aa)
wfikkn2Uncharacterized protein. (559 aa)
A0A1L8ENN6FERM domain-containing protein. (751 aa)
A0A1L8ENV4J domain-containing protein. (411 aa)
Itga4.SIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1073 aa)
Map2.SMicrotubule-associated protein. (1811 aa)
Dhrs7b.SUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
tfap4BHLH domain-containing protein. (333 aa)
adnp-2Uncharacterized protein. (1097 aa)
A0A1L8ESZ5Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (302 aa)
A0A1L8ETZ8Transmembrane channel-like protein. (738 aa)
A0A1L8EUS7Uncharacterized protein. (559 aa)
epb41l5FERM domain-containing protein. (752 aa)
Dnajb2.LJ domain-containing protein. (368 aa)
itga4Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1027 aa)
Map2.LMicrotubule-associated protein. (1769 aa)
dhrs7bUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (323 aa)
Ercc4.LERCC4 domain-containing protein. (924 aa)
wfikkn1Uncharacterized protein. (545 aa)
tfap4-2BHLH domain-containing protein. (333 aa)
ttbk2Uncharacterized protein. (1205 aa)
A0A1L8EZY9Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
Dact1.SUncharacterized protein. (818 aa)
A0A1L8F0E5Uncharacterized protein. (269 aa)
Gnl3l.SCP-type G domain-containing protein. (561 aa)
A0A1L8F397FERM domain-containing protein. (705 aa)
sympkUncharacterized protein. (1202 aa)
rack1WD_REPEATS_REGION domain-containing protein. (276 aa)
gata1Uncharacterized protein. (367 aa)
gemin2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (267 aa)
nesIF rod domain-containing protein; Belongs to the intermediate filament family. (1875 aa)
A0A1L8F6E0WD_REPEATS_REGION domain-containing protein. (165 aa)
A0A1L8F6T4Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
A0A1L8F7X7FERM domain-containing protein. (679 aa)
styxUncharacterized protein. (223 aa)
dact1Uncharacterized protein. (824 aa)
psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
ttbk2-2Protein kinase domain-containing protein. (1215 aa)
nes-2IF rod domain-containing protein; Belongs to the intermediate filament family. (1954 aa)
pex14Pex14_N domain-containing protein. (362 aa)
Park7.SDJ-1_PfpI domain-containing protein. (189 aa)
Bax.LUncharacterized protein. (221 aa)
dkk1Dickkopf_N domain-containing protein. (263 aa)
A0A1L8FJ72Uncharacterized protein. (1846 aa)
waplWAPL domain-containing protein. (1178 aa)
Pex14.LPex14_N domain-containing protein. (377 aa)
sorl1Uncharacterized protein. (2199 aa)
Sri.SUncharacterized protein. (280 aa)
Rock1.SRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1367 aa)
Efhb.LUncharacterized protein. (571 aa)
A0A1L8FX67Uncharacterized protein. (242 aa)
A0A1L8FX70ANK_REP_REGION domain-containing protein. (375 aa)
Dtnbp1.LUncharacterized protein. (317 aa)
arhgap28Rho-GAP domain-containing protein. (661 aa)
Rock1.LRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1360 aa)
ttbk1Protein kinase domain-containing protein. (1376 aa)
plnCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
bag2BAG domain-containing protein. (213 aa)
adipoqC1q domain-containing protein. (233 aa)
A0A1L8G5B3PID domain-containing protein. (180 aa)
ttbk1-2Protein kinase domain-containing protein. (1401 aa)
pln-2Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
bag2-2BAG domain-containing protein. (179 aa)
A0A1L8GE22Uncharacterized protein. (432 aa)
A0A1L8GE55Uncharacterized protein. (401 aa)
A0A1L8GEA7Uncharacterized protein. (1006 aa)
A0A1L8GFZ0Uncharacterized protein. (676 aa)
A0A1L8GHK1BHLH domain-containing protein. (144 aa)
Myod1.LMyogenic factor. (289 aa)
A0A1L8GI81Uncharacterized protein. (431 aa)
A0A1L8GI97Uncharacterized protein. (332 aa)
A0A1L8GI98Uncharacterized protein. (440 aa)
A0A1L8GIA9Uncharacterized protein. (443 aa)
A0A1L8GIC3Uncharacterized protein. (457 aa)
Tfip11.LTuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Belongs to the TFP11/STIP family. (824 aa)
FOGUncharacterized protein. (1203 aa)
Jun.LBZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
Pcsk9.LUncharacterized protein. (676 aa)
pdgfbPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (241 aa)
A0A1L8GPB5Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
cav3.1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
A0A1L8GR35BHLH domain-containing protein. (194 aa)
Smo.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
Tdg.SUDG domain-containing protein. (440 aa)
Ddx11.LHelicase ATP-binding domain-containing protein. (898 aa)
lrrk2Uncharacterized protein. (2514 aa)
Smo.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (524 aa)
A0A1L8H4E2Bin3-type SAM domain-containing protein. (572 aa)
il10Uncharacterized protein. (172 aa)
A0A1L8H766Uncharacterized protein. (198 aa)
A0A1L8H7W7Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (739 aa)
A0A1L8H8B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1033 aa)
ddit3Uncharacterized protein. (207 aa)
rsf1Uncharacterized protein. (1446 aa)
Znf593.LC2H2-type domain-containing protein. (167 aa)
il10-2Uncharacterized protein. (170 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (830 aa)
A0A1L8HG24Uncharacterized protein. (1144 aa)
mitd1MIT domain-containing protein. (276 aa)
A0A1L8HHR6Uncharacterized protein. (174 aa)
A0A1L8HJ50C1q domain-containing protein. (236 aa)
A0A1L8HKV2Amidohydro-rel domain-containing protein. (682 aa)
msx1Homeobox domain-containing protein. (275 aa)
A0A1L8HLI5BHLH domain-containing protein. (272 aa)
A0A1L8HLQ5Uncharacterized protein. (169 aa)
A0A1L8HLQ7Uncharacterized protein. (540 aa)
lef1HMG box domain-containing protein. (372 aa)
Rest.SUncharacterized protein. (1337 aa)
tnksPoly [ADP-ribose] polymerase. (1298 aa)
znf462Uncharacterized protein. (2463 aa)
Habp4.SHABP4_PAI-RBP1 domain-containing protein. (378 aa)
nfatc4RHD domain-containing protein. (1086 aa)
A0A1L8HRQ5PID domain-containing protein. (784 aa)
Lrpap1.LUncharacterized protein. (364 aa)
Crmp1.LAmidohydro-rel domain-containing protein. (682 aa)
hand2BHLH domain-containing protein. (210 aa)
fbxw7Uncharacterized protein. (706 aa)
Rest.LUncharacterized protein. (1421 aa)
A0A1L8HYA8BZIP domain-containing protein. (436 aa)
Habp4.LHABP4_PAI-RBP1 domain-containing protein. (405 aa)
znf462-2Uncharacterized protein. (2463 aa)
nfatc4-2RHD domain-containing protein. (1081 aa)
A0A1L8I2I6PID domain-containing protein. (751 aa)
Arhgap28.SRho-GAP domain-containing protein. (660 aa)
e2f1-2LOC100036852 protein. (426 aa)
LOC496290LOC496290 protein. (461 aa)
sriLOC100037199 protein. (196 aa)
msx1-2LOC100125666 protein. (273 aa)
gtpbp4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (633 aa)
nogNoggin; Belongs to the noggin family. (222 aa)
gata1a-AGATA binding factor-1. (359 aa)
hand1Heart and neural crest derivatives expressed 1. (197 aa)
dkk1-2Dickkopf homolog 1. (259 aa)
hmga2LOC100158391 protein. (105 aa)
pex19LOC733180 protein. (286 aa)
ilrunMGC130859 protein. (278 aa)
pex19-2LOC496096 protein. (283 aa)
atp2a3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1033 aa)
LOC495155LOC495155 protein. (127 aa)
hmga2-2MGC81571 protein. (105 aa)
pdgfb-2Pdgfb protein; Belongs to the PDGF/VEGF growth factor family. (213 aa)
ctnnbip1-2Ctnnbip1b protein. (81 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (159 aa)
adipoq-2MGC84292 protein. (235 aa)
cav1aCaveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
park7Park7 protein. (189 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
ddit3-2Transcription factor GADD153. (211 aa)
fam192aNip30-prov protein. (253 aa)
rack1-2Gnb2l1-prov protein. (317 aa)
Cav-3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
lef1-2Lymphoid enhancer factor XLEF-1. (372 aa)
ctnnbip1-3Beta-catenin-interacting protein. (81 aa)
pin1-2Peptidyl-prolyl cis-trans isomerase. (159 aa)
c-JunC-Jun protein; Belongs to the bZIP family. (312 aa)
Nek2Nek2A. (442 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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