63 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nsfl1c	Uncharacterized protein. (370 aa)
	llgl2	WD_REPEATS_REGION domain-containing protein. (1019 aa)
	clasp1	Uncharacterized protein. (1456 aa)
	nde1	NUDE_C domain-containing protein. (349 aa)
	ankfn1l	Uncharacterized protein. (1291 aa)
	Plk1.S	Serine/threonine-protein kinase PLK. (598 aa)
	Llgl1.S	WD_REPEATS_REGION domain-containing protein. (999 aa)
	A0A1L8ETU8	Uncharacterized protein. (1073 aa)
	Llgl2.L	WD_REPEATS_REGION domain-containing protein. (1017 aa)
	A0A1L8EVB1	Uncharacterized protein. (1480 aa)
	nde1-2	NUDE_C domain-containing protein. (349 aa)
	A0A1L8EY92	Uncharacterized protein. (1197 aa)
	plk1	Serine/threonine-protein kinase PLK. (598 aa)
	A0A1L8EYQ3	LLGL domain-containing protein. (1049 aa)
	A0A1L8F136	Uncharacterized protein. (327 aa)
	A0A1L8F139	Uncharacterized protein. (660 aa)
	A0A1L8F3P2	Uncharacterized protein. (314 aa)
	A0A1L8F5V0	Uncharacterized protein. (328 aa)
	gpsm1	Uncharacterized protein. (639 aa)
	A0A1L8F8I7	Uncharacterized protein. (299 aa)
	Zw10.S	Uncharacterized protein. (776 aa)
	Pax10a	Homeobox domain-containing protein. (281 aa)
	Zw10.L	Uncharacterized protein. (776 aa)
	map4	Microtubule-associated protein. (1211 aa)
	Map4.L	Microtubule-associated protein. (1234 aa)
	Mos.L	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (359 aa)
	ubxn2b	Uncharacterized protein. (350 aa)
	A0A1L8G3L5	BRCT domain-containing protein. (453 aa)
	dynlt1	Uncharacterized protein. (113 aa)
	A0A1L8G9I5	BRCT domain-containing protein. (587 aa)
	A0A1L8G9J6	BRCT domain-containing protein. (154 aa)
	A0A1L8GCB2	Uncharacterized protein. (3837 aa)
	pax6	Uncharacterized protein. (467 aa)
	gpsm2	Uncharacterized protein. (646 aa)
	A0A1L8GIC4	INSC_LBD domain-containing protein. (465 aa)
	pax6-2	Uncharacterized protein. (467 aa)
	A0A1L8GN88	Uncharacterized protein. (664 aa)
	SPDL1	Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (610 aa)
	SPDL1-2	Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (611 aa)
	fam193b-2	FAM193_C domain-containing protein. (894 aa)
	A0A1L8H322	Uncharacterized protein. (751 aa)
	ndc80	DUF5595 domain-containing protein. (638 aa)
	pafah1b1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
	numa1	Uncharacterized protein. (2302 aa)
	A0A1L8HBZ0	DUF5595 domain-containing protein. (640 aa)
	A0A1L8HD59	Uncharacterized protein. (1510 aa)
	PAFAH1B1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (435 aa)
	numa1-2	Uncharacterized protein. (2309 aa)
	Dctn1.S	CAP-Gly domain-containing protein. (1238 aa)
	fam193a	FAM193_C domain-containing protein. (1563 aa)
	A0A1L8HN97	AKAP2_C domain-containing protein. (825 aa)
	dctn1	CAP-Gly domain-containing protein. (1232 aa)
	fam193a-2	FAM193_C domain-containing protein. (1562 aa)
	A0A1L8HTA9	Uncharacterized protein. (3120 aa)
	spry1	Uncharacterized protein. (342 aa)
	Mad2l1.L	HORMA domain-containing protein. (203 aa)
	A0A1L8HWJ9	AKAP2_C domain-containing protein. (679 aa)
	spry1-2	Sprouty 1. (319 aa)
	mad2l1	Mad2l1 protein. (203 aa)
	nsfl1c-2	Nsfl1c protein. (370 aa)
	mapre1	XEB1B protein. (295 aa)
	mapre1-2	XEB1A. (295 aa)
	Pax10b	Paired box 10b. (281 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EVB1	A0A1L8HD59	A0A1L8EVB1	A0A1L8HD59	Uncharacterized protein.	Uncharacterized protein.	0.434
A0A1L8EVB1	Dctn1.S	A0A1L8EVB1	A0A1L8HKF0	Uncharacterized protein.	CAP-Gly domain-containing protein.	0.424
A0A1L8EVB1	Mad2l1.L	A0A1L8EVB1	A0A1L8HUW7	Uncharacterized protein.	HORMA domain-containing protein.	0.568
A0A1L8EVB1	Plk1.S	A0A1L8EVB1	A0A1L8EQN7	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.689
A0A1L8EVB1	dctn1	A0A1L8EVB1	A0A1L8HSN0	Uncharacterized protein.	CAP-Gly domain-containing protein.	0.424
A0A1L8EVB1	mad2l1	A0A1L8EVB1	P79935	Uncharacterized protein.	Mad2l1 protein.	0.568
A0A1L8EVB1	mapre1	A0A1L8EVB1	Q8UW77	Uncharacterized protein.	XEB1B protein.	0.614
A0A1L8EVB1	mapre1-2	A0A1L8EVB1	Q8UW78	Uncharacterized protein.	XEB1A.	0.614
A0A1L8EVB1	plk1	A0A1L8EVB1	A0A1L8EYC7	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.689
A0A1L8EYQ3	Llgl2.L	A0A1L8EYQ3	A0A1L8EUD8	LLGL domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.733
A0A1L8EYQ3	llgl2	A0A1L8EYQ3	A0A1L8EMV4	LLGL domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.733
A0A1L8F136	A0A1L8H322	A0A1L8F136	A0A1L8H322	Uncharacterized protein.	Uncharacterized protein.	0.553
A0A1L8F139	A0A1L8GIC4	A0A1L8F139	A0A1L8GIC4	Uncharacterized protein.	INSC_LBD domain-containing protein.	0.542
A0A1L8F3P2	A0A1L8GIC4	A0A1L8F3P2	A0A1L8GIC4	Uncharacterized protein.	INSC_LBD domain-containing protein.	0.491
A0A1L8F5V0	A0A1L8H322	A0A1L8F5V0	A0A1L8H322	Uncharacterized protein.	Uncharacterized protein.	0.553
A0A1L8F8I7	A0A1L8H322	A0A1L8F8I7	A0A1L8H322	Uncharacterized protein.	Uncharacterized protein.	0.553
A0A1L8G9J6	Plk1.S	A0A1L8G9J6	A0A1L8EQN7	BRCT domain-containing protein.	Serine/threonine-protein kinase PLK.	0.423
A0A1L8G9J6	plk1	A0A1L8G9J6	A0A1L8EYC7	BRCT domain-containing protein.	Serine/threonine-protein kinase PLK.	0.421
A0A1L8GIC4	A0A1L8F139	A0A1L8GIC4	A0A1L8F139	INSC_LBD domain-containing protein.	Uncharacterized protein.	0.542
A0A1L8GIC4	A0A1L8F3P2	A0A1L8GIC4	A0A1L8F3P2	INSC_LBD domain-containing protein.	Uncharacterized protein.	0.491