STRINGSTRING
A0A1L8ELA2 A0A1L8ELA2 szl szl frzb2 frzb2 lef1-2 lef1-2 Cav-3 Cav-3 pygo2-2 pygo2-2 sfrp5 sfrp5 ednra-2 ednra-2 sfrp2-2 sfrp2-2 ctnnb1-2 ctnnb1-2 sostdc1-2 sostdc1-2 pygo2 pygo2 cav1 cav1 jup jup cav1a cav1a siah1-2 siah1-2 Q6DJF2_XENLA Q6DJF2_XENLA plpp3 plpp3 ctnnb1 ctnnb1 gata3 gata3 edn1 edn1 dkk1-2 dkk1-2 wnt7b wnt7b siah2 siah2 xfz8 xfz8 wnt10a-2 wnt10a-2 fz3 fz3 fzd10a fzd10a Xwnt-8b Xwnt-8b tcf7l1-2 tcf7l1-2 wnt6-2 wnt6-2 ednra ednra A0A310U820 A0A310U820 Bcl9l.S Bcl9l.S A0A310TMJ6 A0A310TMJ6 sfrp2 sfrp2 fzd10 fzd10 lef1 lef1 wnt11 wnt11 A0A1L8HJF4 A0A1L8HJF4 lats2-2 lats2-2 wnt10b wnt10b Wnt1.L Wnt1.L ednrb-2 ednrb-2 A0A1L8HF02 A0A1L8HF02 fzd9-2 fzd9-2 A0A1L8HD44 A0A1L8HD44 Bcl9.L Bcl9.L Fzd4.S Fzd4.S A0A1L8HB49 A0A1L8HB49 lats2 lats2 wnt1 wnt1 A0A1L8H9H5 A0A1L8H9H5 ednrb ednrb fzd9 fzd9 bcl9 bcl9 A0A1L8H4V1 A0A1L8H4V1 Sfrp1.L Sfrp1.L Gata3.L Gata3.L wnt16-2 wnt16-2 A0A1L8GYV6 A0A1L8GYV6 scyl2 scyl2 A0A1L8GXA3 A0A1L8GXA3 A0A1L8GVI0 A0A1L8GVI0 Scyl2.S Scyl2.S A0A1L8GU52 A0A1L8GU52 wnt16 wnt16 pygo1 pygo1 tcf7l1 tcf7l1 sfrp1 sfrp1 A0A1L8GR26 A0A1L8GR26 A0A1L8GQT6 A0A1L8GQT6 Wnt5b.S Wnt5b.S cav3.1 cav3.1 A0A1L8GPB5 A0A1L8GPB5 A0A1L8GM78 A0A1L8GM78 siah1 siah1 Lrp5.L Lrp5.L lgr4 lgr4 A0A1L8GHR8 A0A1L8GHR8 Lgr4.S Lgr4.S sdc1 sdc1 Dvl3.L Dvl3.L rspo3 rspo3 fzd3 fzd3 A0A1L8G525 A0A1L8G525 A0A1L8G423 A0A1L8G423 fzd6 fzd6 A0A1L8FX32 A0A1L8FX32 sfrp4 sfrp4 sostdc1 sostdc1 fzd1 fzd1 Fzd8.L Fzd8.L wnt3a wnt3a Wnt9a.S Wnt9a.S Fzd6.S Fzd6.S A0A1L8FQX7 A0A1L8FQX7 A0A1L8FQF4 A0A1L8FQF4 A0A1L8FQD6 A0A1L8FQD6 wnt4-2 wnt4-2 dvl1 dvl1 A0A1L8FLQ0 A0A1L8FLQ0 bcl9l bcl9l A0A1L8FJW6 A0A1L8FJW6 dkk1 dkk1 Tcf7l2.L Tcf7l2.L wnt4 wnt4 A0A1L8FG79 A0A1L8FG79 Sfrp5.S Sfrp5.S A0A1L8FDR5 A0A1L8FDR5 ednrb2 ednrb2 A0A1L8F6W9 A0A1L8F6W9 wnt11b wnt11b A0A1L8F6T4 A0A1L8F6T4 Ednrb2.S Ednrb2.S A0A1L8F2D9 A0A1L8F2D9 A0A1L8F1K1 A0A1L8F1K1 A0A1L8EX74 A0A1L8EX74 fzd7 fzd7 Frzb-1 Frzb-1 wnt6 wnt6 A0A1L8ESG7 A0A1L8ESG7 wnt9b.2 wnt9b.2 A0A1L8ES96 A0A1L8ES96 A0A1L8EPZ4 A0A1L8EPZ4 fzd5 fzd5 Frzb.S Frzb.S wnt10a wnt10a A0A1L8EL97 A0A1L8EL97 fzd2 fzd2 Jup.S Jup.S A0A1L8EKF4 A0A1L8EKF4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1L8ELA2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
szlPutative wnt inhibitor frzb3. (280 aa)
frzb2Putative wnt inhibitor frzb2. (295 aa)
lef1-2Lymphoid enhancer factor XLEF-1. (372 aa)
Cav-3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
pygo2-2Pygopus-2beta. (389 aa)
sfrp5Secreted frizzled-related protein 5. (315 aa)
ednra-2Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (415 aa)
sfrp2-2Sfrp2-prov protein. (298 aa)
ctnnb1-2Ctnnb1-prov protein. (781 aa)
sostdc1-2Wise-A. (213 aa)
pygo2MGC68893 protein. (389 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
jupLOC398496 protein. (737 aa)
cav1aCaveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
siah1-2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa)
Q6DJF2_XENLAProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
plpp3Ppap2ba protein. (307 aa)
ctnnb1Beta-catenin protein. (781 aa)
gata3XGATA-3 protein. (435 aa)
edn1LOC100158354 protein. (221 aa)
dkk1-2Dickkopf homolog 1. (259 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
siah2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
xfz8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
wnt10a-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
fz3Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
fzd10aFrizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
Xwnt-8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
tcf7l1-2Transcription factor XTCF-3b. (554 aa)
wnt6-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ednraLOC100036912 protein; Belongs to the G-protein coupled receptor 1 family. (415 aa)
A0A310U820Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
Bcl9l.SBCL9 domain-containing protein. (1280 aa)
A0A310TMJ6Uncharacterized protein. (605 aa)
sfrp2Uncharacterized protein. (295 aa)
fzd10Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
lef1HMG box domain-containing protein. (372 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
A0A1L8HJF4Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (456 aa)
lats2-2Uncharacterized protein. (1119 aa)
wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
Wnt1.LProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
ednrb-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (431 aa)
A0A1L8HF02Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
fzd9-2Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
A0A1L8HD44FZ domain-containing protein. (183 aa)
Bcl9.LBCL9 domain-containing protein. (1387 aa)
Fzd4.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
A0A1L8HB49Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
lats2Uncharacterized protein. (1112 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
A0A1L8H9H5Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
ednrbG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (431 aa)
fzd9Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
bcl9BCL9 domain-containing protein. (1473 aa)
A0A1L8H4V1Uncharacterized protein. (678 aa)
Sfrp1.LUncharacterized protein. (311 aa)
Gata3.LUncharacterized protein. (454 aa)
wnt16-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
A0A1L8GYV6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
scyl2Protein kinase domain-containing protein. (930 aa)
A0A1L8GXA3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (261 aa)
A0A1L8GVI0Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
Scyl2.SProtein kinase domain-containing protein. (889 aa)
A0A1L8GU52Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (333 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
pygo1PHD-type domain-containing protein. (421 aa)
tcf7l1HMG box domain-containing protein. (551 aa)
sfrp1Uncharacterized protein. (311 aa)
A0A1L8GR26HMG box domain-containing protein. (487 aa)
A0A1L8GQT6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
Wnt5b.SProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
cav3.1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
A0A1L8GPB5Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
A0A1L8GM78acidPPc domain-containing protein. (342 aa)
siah1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
Lrp5.LUncharacterized protein. (1517 aa)
lgr4G_PROTEIN_RECEP_F1_2 domain-containing protein. (953 aa)
A0A1L8GHR8Uncharacterized protein. (300 aa)
Lgr4.SG_PROTEIN_RECEP_F1_2 domain-containing protein. (956 aa)
sdc1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (607 aa)
Dvl3.LUncharacterized protein. (745 aa)
rspo3Uncharacterized protein. (253 aa)
fzd3Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
A0A1L8G525Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (704 aa)
A0A1L8G423Uncharacterized protein. (711 aa)
fzd6Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
A0A1L8FX32Uncharacterized protein. (971 aa)
sfrp4Uncharacterized protein. (353 aa)
sostdc1CTCK domain-containing protein. (213 aa)
fzd1Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
Fzd8.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
Wnt9a.SProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (528 aa)
Fzd6.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
A0A1L8FQX7Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
A0A1L8FQF4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (402 aa)
A0A1L8FQD6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
wnt4-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
dvl1Uncharacterized protein. (606 aa)
A0A1L8FLQ0Uncharacterized protein. (679 aa)
bcl9lBCL9 domain-containing protein. (1281 aa)
A0A1L8FJW6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (431 aa)
dkk1Dickkopf_N domain-containing protein. (263 aa)
Tcf7l2.LHMG box domain-containing protein. (482 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
A0A1L8FG79Uncharacterized protein. (889 aa)
Sfrp5.SUncharacterized protein. (315 aa)
A0A1L8FDR5HMG box domain-containing protein. (482 aa)
ednrb2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (433 aa)
A0A1L8F6W9TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (360 aa)
wnt11bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
A0A1L8F6T4Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
Ednrb2.SG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (435 aa)
A0A1L8F2D9TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (357 aa)
A0A1L8F1K1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
A0A1L8EX74Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
fzd7Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
Frzb-1Uncharacterized protein. (319 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
A0A1L8ESG7Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
wnt9b.2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
A0A1L8ES96Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (554 aa)
A0A1L8EPZ4Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
fzd5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
Frzb.SUncharacterized protein. (319 aa)
wnt10aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
A0A1L8EL97Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (315 aa)
fzd2Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
Jup.SUncharacterized protein. (791 aa)
A0A1L8EKF4FZ domain-containing protein. (134 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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