(13 nodes) Embryonic skeletal joint morphogenesis network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	osr2-2	Uncharacterized protein. (312 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	ctnnb1-2	Ctnnb1-prov protein. (781 aa)
	A0A1L8EPB4	Homeobox domain-containing protein. (274 aa)
	hoxa11	Homeobox domain-containing protein. (298 aa)
	osr2	Uncharacterized protein. (271 aa)
	hoxa11-2	Homeobox domain-containing protein. (299 aa)
	osr1	Uncharacterized protein. (259 aa)
	osr1-2	Uncharacterized protein. (259 aa)
	A0A1L8HA36	Homeobox domain-containing protein. (309 aa)
	A0A1L8HIF1	Homeobox domain-containing protein. (309 aa)
	nog	Noggin; Belongs to the noggin family. (222 aa)
	hoxd11	MGC131014 protein. (274 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ctnnb1	ctnnb1-2	Q63ZT4	Q7ZX35	Beta-catenin protein.	Ctnnb1-prov protein.	0.900
ctnnb1	nog	Q63ZT4	B7ZQ39	Beta-catenin protein.	Noggin; Belongs to the noggin family.	0.454
ctnnb1-2	ctnnb1	Q7ZX35	Q63ZT4	Ctnnb1-prov protein.	Beta-catenin protein.	0.900
hoxa11	osr1	A0A1L8FR88	A0A1L8G5J9	Homeobox domain-containing protein.	Uncharacterized protein.	0.577
hoxa11	osr1-2	A0A1L8FR88	A0A1L8GBX6	Homeobox domain-containing protein.	Uncharacterized protein.	0.576
hoxa11-2	osr1	A0A1L8FW43	A0A1L8G5J9	Homeobox domain-containing protein.	Uncharacterized protein.	0.576
hoxa11-2	osr1-2	A0A1L8FW43	A0A1L8GBX6	Homeobox domain-containing protein.	Uncharacterized protein.	0.575
hoxd11	osr1	Q1RMD8	A0A1L8G5J9	MGC131014 protein.	Uncharacterized protein.	0.623
hoxd11	osr1-2	Q1RMD8	A0A1L8GBX6	MGC131014 protein.	Uncharacterized protein.	0.623
nog	ctnnb1	B7ZQ39	Q63ZT4	Noggin; Belongs to the noggin family.	Beta-catenin protein.	0.454
osr1	hoxa11	A0A1L8G5J9	A0A1L8FR88	Uncharacterized protein.	Homeobox domain-containing protein.	0.577
osr1	hoxa11-2	A0A1L8G5J9	A0A1L8FW43	Uncharacterized protein.	Homeobox domain-containing protein.	0.576
osr1	hoxd11	A0A1L8G5J9	Q1RMD8	Uncharacterized protein.	MGC131014 protein.	0.623
osr1-2	hoxa11	A0A1L8GBX6	A0A1L8FR88	Uncharacterized protein.	Homeobox domain-containing protein.	0.576
osr1-2	hoxa11-2	A0A1L8GBX6	A0A1L8FW43	Uncharacterized protein.	Homeobox domain-containing protein.	0.575
osr1-2	hoxd11	A0A1L8GBX6	Q1RMD8	Uncharacterized protein.	MGC131014 protein.	0.623