(31 nodes) Face morphogenesis network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rab3gap1	Uncharacterized protein. (980 aa)
	Rab3gap1.L	Uncharacterized protein. (978 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	sgpl1	Uncharacterized protein. (573 aa)
	csrnp1	CSRNP_N domain-containing protein. (570 aa)
	dlx5	Homeobox domain-containing protein. (297 aa)
	crispld1	Uncharacterized protein. (514 aa)
	Csrnp1.L	CSRNP_N domain-containing protein. (568 aa)
	Dlx5.L	Homeobox domain-containing protein. (298 aa)
	crispld1-2	Uncharacterized protein. (516 aa)
	ankrd11	ANK_REP_REGION domain-containing protein. (2741 aa)
	crispld2	Uncharacterized protein. (501 aa)
	ep300	Uncharacterized protein. (2495 aa)
	crispld2-2	Uncharacterized protein. (496 aa)
	ep300-2	Uncharacterized protein. (2492 aa)
	stra6	Uncharacterized protein. (639 aa)
	stra6-2	Uncharacterized protein. (639 aa)
	A0A1L8H3M1	Uncharacterized protein. (490 aa)
	A0A1L8H3N4	Uncharacterized protein. (489 aa)
	A0A1L8H3P8	Uncharacterized protein. (494 aa)
	msx1	Homeobox domain-containing protein. (275 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	A0A1L8HRR4	Nipped-B protein. (1728 aa)
	nipbl	Nipped-B protein. (2844 aa)
	msx1-2	LOC100125666 protein. (273 aa)
	nog	Noggin; Belongs to the noggin family. (222 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	pax9	Paired box transcription factor. (360 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Csrnp1.L	msx1	A0A1L8FV49	A0A1L8HKV3	CSRNP_N domain-containing protein.	Homeobox domain-containing protein.	0.871
Csrnp1.L	msx1-2	A0A1L8FV49	A5D8L7	CSRNP_N domain-containing protein.	LOC100125666 protein.	0.871
Dlx5.L	lef1	A0A1L8FVV2	A0A1L8HM07	Homeobox domain-containing protein.	HMG box domain-containing protein.	0.456
Dlx5.L	lef1-2	A0A1L8FVV2	Q90ZB8	Homeobox domain-containing protein.	Lymphoid enhancer factor XLEF-1.	0.456
ankrd11	nipbl	A0A1L8GEN1	A0A1L8I2N9	ANK_REP_REGION domain-containing protein.	Nipped-B protein.	0.508
csrnp1	msx1	A0A1L8FQF9	A0A1L8HKV3	CSRNP_N domain-containing protein.	Homeobox domain-containing protein.	0.871
csrnp1	msx1-2	A0A1L8FQF9	A5D8L7	CSRNP_N domain-containing protein.	LOC100125666 protein.	0.871
dkk1	lef1	A0A1L8FIS6	A0A1L8HM07	Dickkopf_N domain-containing protein.	HMG box domain-containing protein.	0.807
dkk1	lef1-2	A0A1L8FIS6	Q90ZB8	Dickkopf_N domain-containing protein.	Lymphoid enhancer factor XLEF-1.	0.806
dkk1	msx1	A0A1L8FIS6	A0A1L8HKV3	Dickkopf_N domain-containing protein.	Homeobox domain-containing protein.	0.407
dkk1	msx1-2	A0A1L8FIS6	A5D8L7	Dickkopf_N domain-containing protein.	LOC100125666 protein.	0.406
dkk1	nog	A0A1L8FIS6	B7ZQ39	Dickkopf_N domain-containing protein.	Noggin; Belongs to the noggin family.	0.511
dkk1-2	lef1	O57464	A0A1L8HM07	Dickkopf homolog 1.	HMG box domain-containing protein.	0.808
dkk1-2	lef1-2	O57464	Q90ZB8	Dickkopf homolog 1.	Lymphoid enhancer factor XLEF-1.	0.808
dkk1-2	msx1	O57464	A0A1L8HKV3	Dickkopf homolog 1.	Homeobox domain-containing protein.	0.407
dkk1-2	msx1-2	O57464	A5D8L7	Dickkopf homolog 1.	LOC100125666 protein.	0.411
dkk1-2	nog	O57464	B7ZQ39	Dickkopf homolog 1.	Noggin; Belongs to the noggin family.	0.517
dlx5	lef1	A0A1L8FR05	A0A1L8HM07	Homeobox domain-containing protein.	HMG box domain-containing protein.	0.456
dlx5	lef1-2	A0A1L8FR05	Q90ZB8	Homeobox domain-containing protein.	Lymphoid enhancer factor XLEF-1.	0.456
dlx5	msx1-2	A0A1L8FR05	A5D8L7	Homeobox domain-containing protein.	LOC100125666 protein.	0.437