(34 nodes) Regulation of SMAD protein signal transduction network (Xenopus laevis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A0A1L8FX26	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (487 aa)
	slc2a10	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (553 aa)
	A0A1L8EPQ2	Uncharacterized protein. (181 aa)
	A0A1L8EPQ9	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (130 aa)
	Bmpr2.S	Uncharacterized protein. (383 aa)
	A0A1L8EPT8	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (144 aa)
	A0A1L8ESK6	MFS domain-containing protein. (90 aa)
	A0A1L8ESL7	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (411 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1054 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	A0A1L8FDB0	Mothers against decapentaplegic homolog. (514 aa)
	Tgfbr1.S	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (454 aa)
	ccn3	Uncharacterized protein. (345 aa)
	Bmp6.S	TGF_BETA_2 domain-containing protein. (448 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	Nov.L	Uncharacterized protein. (343 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	A0A1L8I2V3	Mothers against decapentaplegic homolog. (510 aa)
	A0A1L8I2I6	PID domain-containing protein. (751 aa)
	Rbpms.L	RRM domain-containing protein. (195 aa)
	A0A1L8HRY9	Mothers against decapentaplegic homolog. (549 aa)
	A0A1L8HRQ5	PID domain-containing protein. (784 aa)
	A0A1L8HMN2	RRM domain-containing protein. (195 aa)
	cilp	Uncharacterized protein. (1175 aa)
	ucma-2	Uncharacterized protein. (138 aa)
	ucma	Uncharacterized protein. (138 aa)
	Cilp.S	Uncharacterized protein. (1188 aa)
	Nup93.L	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (820 aa)
	A0A1L8GAT6	PH domain-containing protein. (824 aa)
	fam89a-2	Uncharacterized protein. (166 aa)
	Bmp2.L	TGF_BETA_2 domain-containing protein. (398 aa)
	bmp2	TGF_BETA_2 domain-containing protein. (398 aa)
	bmp6	TGF_BETA_2 domain-containing protein. (448 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EPQ2	A0A1L8FDB0	A0A1L8EPQ2	A0A1L8FDB0	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.617
A0A1L8EPQ2	A0A1L8FX26	A0A1L8EPQ2	A0A1L8FX26	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.512
A0A1L8EPQ2	A0A1L8HRY9	A0A1L8EPQ2	A0A1L8HRY9	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.617
A0A1L8EPQ2	A0A1L8I2V3	A0A1L8EPQ2	A0A1L8I2V3	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.617
A0A1L8EPQ2	Bmp2.L	A0A1L8EPQ2	A0A1L8G5P4	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.639
A0A1L8EPQ2	Bmp6.S	A0A1L8EPQ2	A0A1L8FS81	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.500
A0A1L8EPQ2	Tgfbr1.S	A0A1L8EPQ2	A0A1L8FRZ0	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.512
A0A1L8EPQ2	bmp2	A0A1L8EPQ2	A0A1L8G1N2	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.639
A0A1L8EPQ2	bmp4	A0A1L8EPQ2	B7ZPR8	Uncharacterized protein.	Bone morphogenetic protein 4.	0.639
A0A1L8EPQ2	bmp4-2	A0A1L8EPQ2	Q91703	Uncharacterized protein.	Bone morphogenetic protein 4.	0.639
A0A1L8EPQ2	bmp6	A0A1L8EPQ2	A0A1L8FXW8	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.500
A0A1L8EPQ9	A0A1L8FDB0	A0A1L8EPQ9	A0A1L8FDB0	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.617
A0A1L8EPQ9	A0A1L8FX26	A0A1L8EPQ9	A0A1L8FX26	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.512
A0A1L8EPQ9	A0A1L8HRY9	A0A1L8EPQ9	A0A1L8HRY9	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.617
A0A1L8EPQ9	A0A1L8I2V3	A0A1L8EPQ9	A0A1L8I2V3	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.617
A0A1L8EPQ9	Bmp2.L	A0A1L8EPQ9	A0A1L8G5P4	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	TGF_BETA_2 domain-containing protein.	0.639
A0A1L8EPQ9	Bmp6.S	A0A1L8EPQ9	A0A1L8FS81	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	TGF_BETA_2 domain-containing protein.	0.500
A0A1L8EPQ9	Tgfbr1.S	A0A1L8EPQ9	A0A1L8FRZ0	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.512
A0A1L8EPQ9	bmp2	A0A1L8EPQ9	A0A1L8G1N2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	TGF_BETA_2 domain-containing protein.	0.639
A0A1L8EPQ9	bmp4	A0A1L8EPQ9	B7ZPR8	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.639