(13 nodes) Epithelial tube branching involved in lung morphogenesis network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dag1-2	Peptidase S72 domain-containing protein. (886 aa)
	Ctsz.S	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (319 aa)
	A0A1L8ESZ5	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (302 aa)
	hoxa5	Homeobox domain-containing protein. (272 aa)
	Rdh10.S	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	hoxa5-2	Homeobox domain-containing protein. (273 aa)
	dag1	Peptidase S72 domain-containing protein. (886 aa)
	ctnnb1-2	Ctnnb1-prov protein. (781 aa)
	hhip-2	Hedgehog-interacting protein. (696 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	spry1-2	Sprouty 1. (319 aa)
	spry1	Uncharacterized protein. (342 aa)
	hhip	EGF-like domain-containing protein. (698 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ctnnb1	ctnnb1-2	Q63ZT4	Q7ZX35	Beta-catenin protein.	Ctnnb1-prov protein.	0.900
ctnnb1	spry1	Q63ZT4	A0A1L8HUP5	Beta-catenin protein.	Uncharacterized protein.	0.428
ctnnb1	spry1-2	Q63ZT4	B7U6L7	Beta-catenin protein.	Sprouty 1.	0.428
ctnnb1-2	ctnnb1	Q7ZX35	Q63ZT4	Ctnnb1-prov protein.	Beta-catenin protein.	0.900
dag1	dag1-2	A0A1L8GH99	A0A1L8GP44	Peptidase S72 domain-containing protein.	Peptidase S72 domain-containing protein.	0.900
dag1-2	dag1	A0A1L8GP44	A0A1L8GH99	Peptidase S72 domain-containing protein.	Peptidase S72 domain-containing protein.	0.900
hhip	hhip-2	A0A1L8HLT8	Q69GM1	EGF-like domain-containing protein.	Hedgehog-interacting protein.	0.900
hhip-2	hhip	Q69GM1	A0A1L8HLT8	Hedgehog-interacting protein.	EGF-like domain-containing protein.	0.900
spry1	ctnnb1	A0A1L8HUP5	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.428
spry1-2	ctnnb1	B7U6L7	Q63ZT4	Sprouty 1.	Beta-catenin protein.	0.428