(60 nodes) Transmembrane receptor protein serine/threonine kinase binding network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8H2G3	TGF_BETA_2 domain-containing protein. (401 aa)
	nodal1	TGF_BETA_2 domain-containing protein. (406 aa)
	nodal	TGF_BETA_2 domain-containing protein. (402 aa)
	Sav1.L	Uncharacterized protein. (388 aa)
	bmp15	TGF_BETA_2 domain-containing protein. (379 aa)
	A0A1L8F2A1	TGF_BETA_2 domain-containing protein. (237 aa)
	sav1	Uncharacterized protein. (384 aa)
	synj2bp	PDZ domain-containing protein. (143 aa)
	Magi2.L	PDZ domain-containing protein. (104 aa)
	A0A1L8GZA6	Uncharacterized protein. (1121 aa)
	Kiaa1324l.L	Uncharacterized protein. (995 aa)
	Bmp7.2.L	TGF_BETA_2 domain-containing protein. (438 aa)
	bmp2	TGF_BETA_2 domain-containing protein. (398 aa)
	nodal5	TGF_BETA_2 domain-containing protein. (384 aa)
	A0A1L8H268	TGF_BETA_2 domain-containing protein. (315 aa)
	A0A1L8H271	TGF_BETA_2 domain-containing protein. (315 aa)
	Xnr5-6	TGF_BETA_2 domain-containing protein. (386 aa)
	A0A1L8H2D1	TGF_BETA_2 domain-containing protein. (401 aa)
	A0A1L8H2D6	TGF_BETA_2 domain-containing protein. (348 aa)
	bmp7.1	TGF_BETA_2 domain-containing protein. (424 aa)
	Nodal3.2.L	TGF_BETA_2 domain-containing protein. (401 aa)
	bmp6	TGF_BETA_2 domain-containing protein. (448 aa)
	Bmper.L	Uncharacterized protein. (687 aa)
	inhba-2	TGF_BETA_2 domain-containing protein. (411 aa)
	Bmp6.S	TGF_BETA_2 domain-containing protein. (448 aa)
	inhba	TGF_BETA_2 domain-containing protein. (411 aa)
	Nodal.L	TGF_BETA_2 domain-containing protein. (402 aa)
	Bmp5.S	TGF_BETA_2 domain-containing protein. (449 aa)
	Bmp2.L	TGF_BETA_2 domain-containing protein. (398 aa)
	bmp5	TGF_BETA_2 domain-containing protein. (449 aa)
	cdh5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (774 aa)
	cdh5-2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (775 aa)
	A0A1L8GRI1	TGF_BETA_2 domain-containing protein. (406 aa)
	A0A1L8GRK4	TGF_BETA_2 domain-containing protein. (263 aa)
	Xnr2	TGF_BETA_2 domain-containing protein. (405 aa)
	A0A1L8GT31	TGF_BETA_2 domain-containing protein. (426 aa)
	Magi2.S	Uncharacterized protein. (1117 aa)
	kiaa1324l	Uncharacterized protein. (996 aa)
	A0A1L8GTX5	PDZ domain-containing protein. (99 aa)
	bmp7.1-2	Osteogenic protein-1 homolog. (424 aa)
	nodal5.2	Xnr5-10. (384 aa)
	nodal6-2	Xnr6. (378 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	synj2bp-2	Outer membrane protein 25. (145 aa)
	Xnr5-3	Xnr5-3. (386 aa)
	nodal6	Xnr6b protein. (379 aa)
	smad6-2	Mothers against decapentaplegic homolog. (354 aa)
	cr1	Cripto-1. (190 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	nodal2	Xnr-2. (405 aa)
	smad6	Mothers against decapentaplegic homolog. (352 aa)
	A0A310TN86	Pyrin domain-containing protein. (91 aa)
	Tdgf1.2.L	CFC domain-containing protein. (194 aa)
	Gdf15.L	TGF_BETA_2 domain-containing protein. (371 aa)
	Cr1b	CFC domain-containing protein. (188 aa)
	tdgf1.2	CFC domain-containing protein. (199 aa)
	gdf15	TGF_BETA_2 domain-containing protein. (377 aa)
	A0A1L8HFV1	TGF_BETA_2 domain-containing protein. (422 aa)
	A0A1L8H7Y8	TGF_BETA_2 domain-containing protein. (566 aa)
	A0A1L8H2G4	TGF_BETA_2 domain-containing protein. (336 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GRI1	cr1	A0A1L8GRI1	B7ZQM8	TGF_BETA_2 domain-containing protein.	Cripto-1.	0.830
A0A1L8GRI1	inhba	A0A1L8GRI1	A0A1L8FRS5	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.668
A0A1L8GRI1	inhba-2	A0A1L8GRI1	A0A1L8FWM6	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.668
A0A1L8GRI1	tdgf1.2	A0A1L8GRI1	A0A1L8HPC7	TGF_BETA_2 domain-containing protein.	CFC domain-containing protein.	0.702
A0A1L8GT31	Bmp2.L	A0A1L8GT31	A0A1L8G5P4	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.556
A0A1L8GT31	bmp2	A0A1L8GT31	A0A1L8G1N2	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.554
A0A1L8GT31	bmp4	A0A1L8GT31	B7ZPR8	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 4.	0.538
A0A1L8GT31	bmp4-2	A0A1L8GT31	Q91703	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 4.	0.539
A0A1L8H2D1	cr1	A0A1L8H2D1	B7ZQM8	TGF_BETA_2 domain-containing protein.	Cripto-1.	0.843
A0A1L8H2D1	inhba	A0A1L8H2D1	A0A1L8FRS5	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.669
A0A1L8H2D1	inhba-2	A0A1L8H2D1	A0A1L8FWM6	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.669
A0A1L8H2D1	tdgf1.2	A0A1L8H2D1	A0A1L8HPC7	TGF_BETA_2 domain-containing protein.	CFC domain-containing protein.	0.699
A0A1L8H2D6	cr1	A0A1L8H2D6	B7ZQM8	TGF_BETA_2 domain-containing protein.	Cripto-1.	0.843
A0A1L8H2D6	inhba	A0A1L8H2D6	A0A1L8FRS5	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.669
A0A1L8H2D6	inhba-2	A0A1L8H2D6	A0A1L8FWM6	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.669
A0A1L8H2D6	tdgf1.2	A0A1L8H2D6	A0A1L8HPC7	TGF_BETA_2 domain-containing protein.	CFC domain-containing protein.	0.699
A0A1L8H2G3	cr1	A0A1L8H2G3	B7ZQM8	TGF_BETA_2 domain-containing protein.	Cripto-1.	0.843
A0A1L8H2G3	inhba	A0A1L8H2G3	A0A1L8FRS5	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.669
A0A1L8H2G3	inhba-2	A0A1L8H2G3	A0A1L8FWM6	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.669
A0A1L8H2G3	tdgf1.2	A0A1L8H2G3	A0A1L8HPC7	TGF_BETA_2 domain-containing protein.	CFC domain-containing protein.	0.699