34 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8EKQ1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa)
	baiap2	Uncharacterized protein. (579 aa)
	med1l	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa)
	baiap2-2	Uncharacterized protein. (523 aa)
	A0A1L8F412	Uncharacterized protein. (313 aa)
	A0A1L8F438	Uncharacterized protein. (331 aa)
	A0A1L8F975	Uncharacterized protein. (331 aa)
	zfp36	CCCH zinc finger protein C3H-1. (313 aa)
	A0A1L8FB00	Uncharacterized protein. (242 aa)
	A0A1L8FB50	Uncharacterized protein. (345 aa)
	A0A1L8FG16	Uncharacterized protein. (559 aa)
	Errfi1.S	Inhibitor_Mig-6 domain-containing protein. (404 aa)
	garem1	CABIT domain-containing protein. (876 aa)
	Med1.L	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (649 aa)
	garem1-2	CABIT domain-containing protein. (878 aa)
	zfp36l2	Uncharacterized protein. (363 aa)
	garem2	CABIT domain-containing protein. (900 aa)
	Syap1.S	BSD domain-containing protein. (364 aa)
	bag4-2	BAG domain-containing protein. (405 aa)
	bag4	BAG domain-containing protein. (402 aa)
	Zfp36l2.L	Uncharacterized protein. (364 aa)
	Mars	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (905 aa)
	inpp5k	IPPc domain-containing protein. (476 aa)
	Syap1.L	BSD domain-containing protein. (361 aa)
	Mars.L	WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (655 aa)
	A0A1L8HIA2	Uncharacterized protein. (178 aa)
	A0A1L8HRQ5	PID domain-containing protein. (784 aa)
	A0A1L8I158	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
	A0A1L8I2I6	PID domain-containing protein. (751 aa)
	zpr1	LOC100158293 protein. (446 aa)
	garem2-2	MGC84378 protein. (898 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	errfi1	MGC68521 protein. (401 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKQ1	A0A1L8HIA2	A0A1L8EKQ1	A0A1L8HIA2	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.475
A0A1L8EKQ1	Mars	A0A1L8EKQ1	A0A1L8H9X3	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.475
A0A1L8EKQ1	Mars.L	A0A1L8EKQ1	A0A1L8HI26	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.475
A0A1L8HIA2	A0A1L8EKQ1	A0A1L8HIA2	A0A1L8EKQ1	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.475
A0A1L8HIA2	Mars	A0A1L8HIA2	A0A1L8H9X3	Uncharacterized protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.976
A0A1L8HIA2	Mars.L	A0A1L8HIA2	A0A1L8HI26	Uncharacterized protein.	WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.976
A0A1L8HIA2	Med1.L	A0A1L8HIA2	A0A1L8FWZ0	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.475
A0A1L8HIA2	med1l	A0A1L8HIA2	A0A1L8ERZ1	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.475
Mars	A0A1L8EKQ1	A0A1L8H9X3	A0A1L8EKQ1	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.475
Mars	A0A1L8HIA2	A0A1L8H9X3	A0A1L8HIA2	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Uncharacterized protein.	0.976
Mars	Mars.L	A0A1L8H9X3	A0A1L8HI26	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.997
Mars	Med1.L	A0A1L8H9X3	A0A1L8FWZ0	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.475
Mars	med1l	A0A1L8H9X3	A0A1L8ERZ1	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.475
Mars.L	A0A1L8EKQ1	A0A1L8HI26	A0A1L8EKQ1	WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.475
Mars.L	A0A1L8HIA2	A0A1L8HI26	A0A1L8HIA2	WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Uncharacterized protein.	0.976
Mars.L	Mars	A0A1L8HI26	A0A1L8H9X3	WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.997
Mars.L	Med1.L	A0A1L8HI26	A0A1L8FWZ0	WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.475
Mars.L	med1l	A0A1L8HI26	A0A1L8ERZ1	WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.475
Med1.L	A0A1L8HIA2	A0A1L8FWZ0	A0A1L8HIA2	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.475
Med1.L	Mars	A0A1L8FWZ0	A0A1L8H9X3	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.475