(6 nodes) Nuclear protein quality control by the ubiquitin-proteasome system network (Xenopus laevis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Klhl15.S	BTB domain-containing protein. (241 aa)
	Akirin2.S	Uncharacterized protein. (272 aa)
	cul3	CULLIN_2 domain-containing protein; Belongs to the cullin family. (768 aa)
	A0A1L8G9E5	Uncharacterized protein. (181 aa)
	cul3-2	CULLIN_2 domain-containing protein; Belongs to the cullin family. (768 aa)
	klhl15	BTB domain-containing protein. (604 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Klhl15.S	cul3	A0A1L8H5X1	A0A1L8G4G3	BTB domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.852
Klhl15.S	cul3-2	A0A1L8H5X1	A0A1L8GAJ9	BTB domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.852
cul3	Klhl15.S	A0A1L8G4G3	A0A1L8H5X1	CULLIN_2 domain-containing protein; Belongs to the cullin family.	BTB domain-containing protein.	0.852
cul3	cul3-2	A0A1L8G4G3	A0A1L8GAJ9	CULLIN_2 domain-containing protein; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.900
cul3	klhl15	A0A1L8G4G3	A0A1L8HDK2	CULLIN_2 domain-containing protein; Belongs to the cullin family.	BTB domain-containing protein.	0.852
cul3-2	Klhl15.S	A0A1L8GAJ9	A0A1L8H5X1	CULLIN_2 domain-containing protein; Belongs to the cullin family.	BTB domain-containing protein.	0.852
cul3-2	cul3	A0A1L8GAJ9	A0A1L8G4G3	CULLIN_2 domain-containing protein; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.900
cul3-2	klhl15	A0A1L8GAJ9	A0A1L8HDK2	CULLIN_2 domain-containing protein; Belongs to the cullin family.	BTB domain-containing protein.	0.852
klhl15	cul3	A0A1L8HDK2	A0A1L8G4G3	BTB domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.852
klhl15	cul3-2	A0A1L8HDK2	A0A1L8GAJ9	BTB domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.852