117 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cdk5rap3.S	Uncharacterized protein. (505 aa)
	hexim1	Uncharacterized protein. (283 aa)
	A0A1L8ELC0	Uncharacterized protein. (80 aa)
	ptpn1	Tyrosine-protein phosphatase non-receptor type. (430 aa)
	myocd	SAP domain-containing protein. (960 aa)
	Dusp19.S	Uncharacterized protein. (132 aa)
	tmem130	PKD domain-containing protein. (426 aa)
	prkar1b	Uncharacterized protein. (380 aa)
	Plk1.S	Serine/threonine-protein kinase PLK. (598 aa)
	tfap4	BHLH domain-containing protein. (333 aa)
	Cdk5rap3.L	Uncharacterized protein. (532 aa)
	hexim1-2	Uncharacterized protein. (285 aa)
	A0A1L8ESJ5	Uncharacterized protein. (80 aa)
	cdk5rap1	Uncharacterized protein. (565 aa)
	Myocd.L	SAP domain-containing protein. (959 aa)
	Dusp19.L	Uncharacterized protein. (216 aa)
	prkar1b-2	Uncharacterized protein. (380 aa)
	Tmem130.L	PKD domain-containing protein. (358 aa)
	plk1	Serine/threonine-protein kinase PLK. (598 aa)
	tfap4-2	BHLH domain-containing protein. (333 aa)
	A0A1L8F273	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (164 aa)
	spry3	Uncharacterized protein. (289 aa)
	A0A1L8F6T4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
	A0A1L8F6U2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (164 aa)
	spry3-2	Uncharacterized protein. (286 aa)
	gba	Glucosylceramidase. (519 aa)
	ptpn6	Uncharacterized protein. (687 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (722 aa)
	ptprh	Uncharacterized protein. (1051 aa)
	Xicl	Uncharacterized protein. (266 aa)
	Sirt1.L	Deacetylase sirtuin-type domain-containing protein. (722 aa)
	sorl1	Uncharacterized protein. (2199 aa)
	ptprh-2	Uncharacterized protein. (1228 aa)
	lyn	Tyrosine-protein kinase. (508 aa)
	pkia	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
	Dtnbp1.L	Uncharacterized protein. (317 aa)
	lyn-2	Tyrosine-protein kinase. (508 aa)
	A0A1L8FZB0	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
	A0A1L8G129	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (477 aa)
	aida	Uncharacterized protein. (309 aa)
	bmp2	TGF_BETA_2 domain-containing protein. (398 aa)
	Tnfaip3.S	Uncharacterized protein. (781 aa)
	Agt.S	SERPIN domain-containing protein; Belongs to the serpin family. (466 aa)
	Lats1.S	Uncharacterized protein. (1118 aa)
	A0A1L8G402	Uncharacterized protein. (176 aa)
	adipoq	C1q domain-containing protein. (233 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	Bmp2.L	TGF_BETA_2 domain-containing protein. (398 aa)
	A0A1L8G644	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (477 aa)
	aida-2	Uncharacterized protein. (309 aa)
	Agt.L	SERPIN domain-containing protein; Belongs to the serpin family. (466 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	A0A1L8GCV6	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (423 aa)
	hipk3	Protein kinase domain-containing protein. (1222 aa)
	cdkn2c	ANK_REP_REGION domain-containing protein. (168 aa)
	A0A1L8GHR4	Uncharacterized protein. (405 aa)
	A0A1L8GI50	Uncharacterized protein. (768 aa)
	hipk3-2	Protein kinase domain-containing protein. (1214 aa)
	A0A1L8GJT0	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (424 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	Men1.L	Uncharacterized protein. (675 aa)
	cdkn2c-2	ANK_REP_REGION domain-containing protein. (168 aa)
	A0A1L8GPB5	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
	cav3.1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
	A0A1L8GPR3	Uncharacterized protein. (404 aa)
	fbxo7	F-box domain-containing protein. (500 aa)
	A0A1L8GQT6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	Cdkn1b.S	Uncharacterized protein. (152 aa)
	Prkar2b.S	Uncharacterized protein. (402 aa)
	spry4	Uncharacterized protein. (297 aa)
	A0A1L8GWC5	Uncharacterized protein. (149 aa)
	spry4-2	Uncharacterized protein. (297 aa)
	A0A1L8GYL7	Protein kinase domain-containing protein. (565 aa)
	A0A1L8GZ80	Uncharacterized protein. (406 aa)
	cdkn2d	ANK_REP_REGION domain-containing protein. (161 aa)
	A0A1L8H6B5	Uncharacterized protein. (137 aa)
	Nf1.S	Uncharacterized protein. (2774 aa)
	lats2	Uncharacterized protein. (1112 aa)
	chordc1	Uncharacterized protein. (334 aa)
	inpp5k	IPPc domain-containing protein. (476 aa)
	cdkn1a	Uncharacterized protein. (261 aa)
	nf1	Uncharacterized protein. (2759 aa)
	spry2	Uncharacterized protein. (307 aa)
	lats2-2	Uncharacterized protein. (1119 aa)
	A0A1L8HJ50	C1q domain-containing protein. (236 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (581 aa)
	cdkn2b	ANK_REP_REGION domain-containing protein. (125 aa)
	Sh2b3.S	SH2 domain-containing protein. (617 aa)
	hmgcr	3-hydroxy-3-methylglutaryl coenzyme A reductase. (881 aa)
	A0A1L8HTS5	Cyclic nucleotide-binding domain-containing protein. (329 aa)
	sfrp2	Uncharacterized protein. (295 aa)
	spry1	Uncharacterized protein. (342 aa)
	paqr3	Uncharacterized protein. (311 aa)
	sh2b3	Uncharacterized protein. (618 aa)
	A0A310TN86	Pyrin domain-containing protein. (91 aa)
	A0A310TP32	Uncharacterized protein. (202 aa)
	A0A310UBU8	Uncharacterized protein. (244 aa)
	h2afy	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (369 aa)
	spry1-2	Sprouty 1. (319 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	cdkn2b-2	MGC154405 protein. (125 aa)
	ptpn6-2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (587 aa)
	cdkn2d-2	Ank2-prov protein. (161 aa)
	prkar1a	MGC82149 protein. (381 aa)
	adipoq-2	MGC84292 protein. (235 aa)
	hmgcr-2	3-hydroxy-3-methylglutaryl coenzyme A reductase. (883 aa)
	ptpn1-2	Tyrosine-protein phosphatase non-receptor type. (428 aa)
	prkar1a-2	Prkar1a protein. (381 aa)
	cav1a	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	paqr3-2	MGC83905 protein. (309 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	sfrp2-2	Sfrp2-prov protein. (298 aa)
	cav3.2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
	Cav-3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
	spry2-2	LOC398313 protein. (314 aa)
	cdknx	Cyclin-dependent kinase inhibitor p28. (209 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ELC0	A0A1L8FZB0	A0A1L8ELC0	A0A1L8FZB0	Uncharacterized protein.	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family.	0.533
A0A1L8ELC0	pkia	A0A1L8ELC0	A0A1L8FTD4	Uncharacterized protein.	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family.	0.533
A0A1L8ESJ5	A0A1L8FZB0	A0A1L8ESJ5	A0A1L8FZB0	Uncharacterized protein.	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family.	0.533
A0A1L8ESJ5	pkia	A0A1L8ESJ5	A0A1L8FTD4	Uncharacterized protein.	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family.	0.533
A0A1L8F273	A0A1L8F6T4	A0A1L8F273	A0A1L8F6T4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.419
A0A1L8F273	Lrp5.L	A0A1L8F273	A0A1L8GJX4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.486
A0A1L8F273	cav1	A0A1L8F273	Q6P7G5	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.472
A0A1L8F273	cav1a	A0A1L8F273	Q6IRP8	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.636
A0A1L8F273	cav3.1	A0A1L8F273	A0A1L8GPP4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.425
A0A1L8F6T4	A0A1L8F273	A0A1L8F6T4	A0A1L8F273	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.419
A0A1L8F6T4	A0A1L8F6U2	A0A1L8F6T4	A0A1L8F6U2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.419
A0A1L8F6T4	A0A1L8GQT6	A0A1L8F6T4	A0A1L8GQT6	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.808
A0A1L8F6T4	Lrp5.L	A0A1L8F6T4	A0A1L8GJX4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.736
A0A1L8F6T4	cav3.2	A0A1L8F6T4	Q8AVS7	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.601
A0A1L8F6T4	lyn	A0A1L8F6T4	A0A1L8FT48	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.423
A0A1L8F6T4	lyn-2	A0A1L8F6T4	A0A1L8FZ11	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.423
A0A1L8F6U2	A0A1L8F6T4	A0A1L8F6U2	A0A1L8F6T4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.419
A0A1L8F6U2	Lrp5.L	A0A1L8F6U2	A0A1L8GJX4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.486
A0A1L8F6U2	cav1	A0A1L8F6U2	Q6P7G5	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.470
A0A1L8F6U2	cav1a	A0A1L8F6U2	Q6IRP8	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.633