STRINGSTRING
cyld cyld tnn tnn sox10-2 sox10-2 A0A1L8GPB5 A0A1L8GPB5 cav3.1 cav3.1 sfrp1 sfrp1 Scyl2.S Scyl2.S csnk1a1 csnk1a1 ptpro ptpro csnk1a1-2 csnk1a1-2 A0A1L8GXP7 A0A1L8GXP7 nkx2-5 nkx2-5 scyl2 scyl2 Sfrp1.L Sfrp1.L A0A1L8H3P0 A0A1L8H3P0 A0A1L8H5Q6 A0A1L8H5Q6 Sox13.S Sox13.S A0A1L8H7T2 A0A1L8H7T2 A0A1L8H7V5 A0A1L8H7V5 A0A1L8H7X8 A0A1L8H7X8 ddit3 ddit3 gli1 gli1 Pfdn5.S Pfdn5.S A0A1L8HAM9 A0A1L8HAM9 lats2 lats2 A0A1L8HB49 A0A1L8HB49 Fzd4.S Fzd4.S A0A1L8HBB5 A0A1L8HBB5 A0A1L8HBT3 A0A1L8HBT3 frzb2 frzb2 ctnnbip1-3 ctnnbip1-3 szl szl A0A1L8HBT4 A0A1L8HBT4 A0A1L8HBY8 A0A1L8HBY8 A0A1L8HFH3 A0A1L8HFH3 ubac2 ubac2 Gli1.L Gli1.L pfdn5 pfdn5 amer2 amer2 lats2-2 lats2-2 A0A1L8HJF4 A0A1L8HJF4 wnt11 wnt11 A0A1L8HKH2 A0A1L8HKH2 A0A1L8HKN5 A0A1L8HKN5 shisa3 shisa3 tmem131l tmem131l jade1 jade1 dkk2 dkk2 A0A1L8HN72 A0A1L8HN72 stk11 stk11 tle4 tle4 A0A1L8HPC6 A0A1L8HPC6 Kremen1.S Kremen1.S Znrf3.S Znrf3.S A0A1L8HR18 A0A1L8HR18 apc apc A0A1L8HRQ5 A0A1L8HRQ5 A0A1L8HSG6 A0A1L8HSG6 shisa3-2 shisa3-2 tmem131l-2 tmem131l-2 sfrp2 sfrp2 A0A1L8HUV5 A0A1L8HUV5 Apc2.L Apc2.L stk11-2 stk11-2 tle5 tle5 Esg2-A Esg2-A A0A1L8HYZ3 A0A1L8HYZ3 A0A1L8I050 A0A1L8I050 kremen1 kremen1 znrf3 znrf3 apc-2 apc-2 Mcc Mcc A0A1L8I2I6 A0A1L8I2I6 A0A310UDM1 A0A310UDM1 emd emd nog nog invs-a invs-a mespa mespa tpbg-2 tpbg-2 sox9-a sox9-a dkk1-2 dkk1-2 ruvbl2 ruvbl2 ctnnb1 ctnnb1 ctnnbip1-2 ctnnbip1-2 tle2 tle2 g3bp1 g3bp1 cav1a cav1a cav1 cav1 sostdc1-2 sostdc1-2 nkx2-5-2 nkx2-5-2 ddit3-2 ddit3-2 ctnnb1-2 ctnnb1-2 g3bp1-2 g3bp1-2 sfrp2-2 sfrp2-2 sfrp5 sfrp5 Cav-3 Cav-3 dkk2-2 dkk2-2 Stk4.S Stk4.S notum notum A0A1L8ENI4 A0A1L8ENI4 Frzb.S Frzb.S Axin1.S Axin1.S Kremen2.S Kremen2.S stk4 stk4 Notum.L Notum.L A0A1L8EUY4 A0A1L8EUY4 Frzb-1 Frzb-1 Notum2 Notum2 axin1 axin1 kremen2 kremen2 A0A1L8EZF8 A0A1L8EZF8 Dact1.S Dact1.S A0A1L8F2I8 A0A1L8F2I8 A0A1L8F3G8 A0A1L8F3G8 A0A1L8F5F3 A0A1L8F5F3 A0A1L8F6T4 A0A1L8F6T4 wnt11b wnt11b A0A1L8F791 A0A1L8F791 A0A1L8F839 A0A1L8F839 dact1 dact1 bicc1 bicc1 LZTS2 LZTS2 Sfrp5.S Sfrp5.S A0A1L8FFM1 A0A1L8FFM1 A0A1L8FG98 A0A1L8FG98 gsk3a gsk3a A0A1L8FH29 A0A1L8FH29 A0A1L8FH58 A0A1L8FH58 A0A1L8FH59 A0A1L8FH59 A0A1L8FH67 A0A1L8FH67 A0A1L8FH77 A0A1L8FH77 A0A1L8FH84 A0A1L8FH84 Bicc1.L Bicc1.L dkk1 dkk1 lzts2 lzts2 A0A1L8FKX2 A0A1L8FKX2 A0A1L8FM60 A0A1L8FM60 nphp4.2 nphp4.2 A0A1L8FN20 A0A1L8FN20 gli3 gli3 tmem64 tmem64 stk3 stk3 cthrc1 cthrc1 sostdc1 sostdc1 Nphp3.L Nphp3.L gli3-2 gli3-2 sfrp4 sfrp4 A0A1L8FXZ1 A0A1L8FXZ1 tmem64-2 tmem64-2 A0A1L8FZM9 A0A1L8FZM9 cthrc1-2 cthrc1-2 A0A1L8G0A4 A0A1L8G0A4 Lats1.S Lats1.S ankrd6 ankrd6 ankrd6-2 ankrd6-2 tpbg tpbg sdhaf2 sdhaf2 mdk mdk Dkk3.S Dkk3.S A0A1L8GEK8 A0A1L8GEK8 A0A1L8GER2 A0A1L8GER2 A0A1L8GH13 A0A1L8GH13 sox10 sox10 A0A1L8GHR8 A0A1L8GHR8 A0A1L8GIG9 A0A1L8GIG9 Mdk.L Mdk.L frmd8 frmd8 nkd1 nkd1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cyldUncharacterized protein. (973 aa)
tnnUncharacterized protein. (1091 aa)
sox10-2HMG box domain-containing protein. (446 aa)
A0A1L8GPB5Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
cav3.1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
sfrp1Uncharacterized protein. (311 aa)
Scyl2.SProtein kinase domain-containing protein. (889 aa)
csnk1a1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
ptproUncharacterized protein. (1289 aa)
csnk1a1-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)
A0A1L8GXP7Uncharacterized protein. (147 aa)
nkx2-5Homeobox domain-containing protein. (300 aa)
scyl2Protein kinase domain-containing protein. (930 aa)
Sfrp1.LUncharacterized protein. (311 aa)
A0A1L8H3P0Uncharacterized protein. (164 aa)
A0A1L8H5Q6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
Sox13.SHMG box domain-containing protein. (567 aa)
A0A1L8H7T2Uncharacterized protein. (200 aa)
A0A1L8H7V5Uncharacterized protein. (108 aa)
A0A1L8H7X8Uncharacterized protein. (1433 aa)
ddit3Uncharacterized protein. (207 aa)
gli1Uncharacterized protein. (1361 aa)
Pfdn5.SUncharacterized protein. (152 aa)
A0A1L8HAM9Uncharacterized protein. (624 aa)
lats2Uncharacterized protein. (1112 aa)
A0A1L8HB49Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Fzd4.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
A0A1L8HBB5LRRCT domain-containing protein. (354 aa)
A0A1L8HBT3Uncharacterized protein. (28 aa)
frzb2Putative wnt inhibitor frzb2. (295 aa)
ctnnbip1-3Beta-catenin-interacting protein. (81 aa)
szlPutative wnt inhibitor frzb3. (280 aa)
A0A1L8HBT4Protein kinase domain-containing protein. (64 aa)
A0A1L8HBY8Protein kinase domain-containing protein. (298 aa)
A0A1L8HFH3Uncharacterized protein. (1374 aa)
ubac2UBA domain-containing protein. (338 aa)
Gli1.LUncharacterized protein. (1362 aa)
pfdn5Uncharacterized protein. (152 aa)
amer2Uncharacterized protein. (567 aa)
lats2-2Uncharacterized protein. (1119 aa)
A0A1L8HJF4Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (456 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
A0A1L8HKH2Uncharacterized protein. (655 aa)
A0A1L8HKN5Uncharacterized protein. (218 aa)
shisa3Uncharacterized protein. (232 aa)
tmem131lTMEM131_like domain-containing protein. (1608 aa)
jade1Uncharacterized protein. (827 aa)
dkk2Dickkopf_N domain-containing protein. (255 aa)
A0A1L8HN72Uncharacterized protein. (2243 aa)
stk11Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
tle4Uncharacterized protein. (773 aa)
A0A1L8HPC6Uncharacterized protein. (780 aa)
Kremen1.SKremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (452 aa)
Znrf3.SRING-type domain-containing protein. (848 aa)
A0A1L8HR18Uncharacterized protein. (1030 aa)
apcUncharacterized protein. (2827 aa)
A0A1L8HRQ5PID domain-containing protein. (784 aa)
A0A1L8HSG6Uncharacterized protein. (218 aa)
shisa3-2Uncharacterized protein. (234 aa)
tmem131l-2TMEM131_like domain-containing protein. (1606 aa)
sfrp2Uncharacterized protein. (295 aa)
A0A1L8HUV5Uncharacterized protein. (829 aa)
Apc2.LUncharacterized protein. (2148 aa)
stk11-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
tle5TLE_N domain-containing protein. (198 aa)
Esg2-AUncharacterized protein. (610 aa)
A0A1L8HYZ3Uncharacterized protein. (780 aa)
A0A1L8I050Uncharacterized protein; Belongs to the peptidase C19 family. (807 aa)
kremen1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
znrf3RING-type domain-containing protein. (854 aa)
apc-2Uncharacterized protein. (2834 aa)
MccUncharacterized protein. (778 aa)
A0A1L8I2I6PID domain-containing protein. (751 aa)
A0A310UDM1Uncharacterized protein. (141 aa)
emdXemd1 protein. (180 aa)
nogNoggin; Belongs to the noggin family. (222 aa)
invs-aInversin. (1007 aa)
mespaBHLH transcription factor mespa. (283 aa)
tpbg-2Wnt-activated inhibitory factor 1a.2. (403 aa)
sox9-aSex determining region Y-box 9. (477 aa)
dkk1-2Dickkopf homolog 1. (259 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (462 aa)
ctnnb1Beta-catenin protein. (781 aa)
ctnnbip1-2Ctnnbip1b protein. (81 aa)
tle2ESG protein. (768 aa)
g3bp1MGC80186 protein. (470 aa)
cav1aCaveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
sostdc1-2Wise-A. (213 aa)
nkx2-5-2Nkx2.5 protein. (299 aa)
ddit3-2Transcription factor GADD153. (211 aa)
ctnnb1-2Ctnnb1-prov protein. (781 aa)
g3bp1-2G3bp-prov protein. (470 aa)
sfrp2-2Sfrp2-prov protein. (298 aa)
sfrp5Secreted frizzled-related protein 5. (315 aa)
Cav-3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
dkk2-2Dickkopf homolog 2. (255 aa)
Stk4.SUncharacterized protein. (485 aa)
notumUncharacterized protein. (488 aa)
A0A1L8ENI4Uncharacterized protein. (815 aa)
Frzb.SUncharacterized protein. (319 aa)
Axin1.SUncharacterized protein. (839 aa)
Kremen2.SUncharacterized protein. (421 aa)
stk4Uncharacterized protein. (485 aa)
Notum.LUncharacterized protein. (386 aa)
A0A1L8EUY4Uncharacterized protein. (818 aa)
Frzb-1Uncharacterized protein. (319 aa)
Notum2Uncharacterized protein. (459 aa)
axin1Uncharacterized protein. (841 aa)
kremen2Uncharacterized protein. (420 aa)
A0A1L8EZF8OTU domain-containing protein. (415 aa)
Dact1.SUncharacterized protein. (818 aa)
A0A1L8F2I8Uncharacterized protein. (1067 aa)
A0A1L8F3G8Uncharacterized protein. (373 aa)
A0A1L8F5F3OTU domain-containing protein. (493 aa)
A0A1L8F6T4Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
wnt11bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
A0A1L8F791Uncharacterized protein. (1177 aa)
A0A1L8F839Uncharacterized protein. (416 aa)
dact1Uncharacterized protein. (824 aa)
bicc1SAM domain-containing protein. (963 aa)
LZTS2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (666 aa)
Sfrp5.SUncharacterized protein. (315 aa)
A0A1L8FFM1Uncharacterized protein. (588 aa)
A0A1L8FG98Uncharacterized protein. (179 aa)
gsk3aProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (424 aa)
A0A1L8FH29Uncharacterized protein. (280 aa)
A0A1L8FH58RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (47 aa)
A0A1L8FH59RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (65 aa)
A0A1L8FH67RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (122 aa)
A0A1L8FH77RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (108 aa)
A0A1L8FH84RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (54 aa)
Bicc1.LSAM domain-containing protein. (989 aa)
dkk1Dickkopf_N domain-containing protein. (263 aa)
lzts2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (701 aa)
A0A1L8FKX2Uncharacterized protein. (305 aa)
A0A1L8FM60Uncharacterized protein. (179 aa)
nphp4.2Uncharacterized protein. (1440 aa)
A0A1L8FN20Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
gli3Uncharacterized protein. (1565 aa)
tmem64Uncharacterized protein. (307 aa)
stk3Uncharacterized protein. (493 aa)
cthrc1Uncharacterized protein. (235 aa)
sostdc1CTCK domain-containing protein. (213 aa)
Nphp3.LTPR_REGION domain-containing protein. (1262 aa)
gli3-2Uncharacterized protein. (1568 aa)
sfrp4Uncharacterized protein. (353 aa)
A0A1L8FXZ1Uncharacterized protein. (253 aa)
tmem64-2Uncharacterized protein. (315 aa)
A0A1L8FZM9Uncharacterized protein. (612 aa)
cthrc1-2Uncharacterized protein. (235 aa)
A0A1L8G0A4Uncharacterized protein; Belongs to the peptidase C19 family. (846 aa)
Lats1.SUncharacterized protein. (1118 aa)
ankrd6ANK_REP_REGION domain-containing protein. (776 aa)
ankrd6-2ANK_REP_REGION domain-containing protein. (776 aa)
tpbgLRRCT domain-containing protein. (404 aa)
sdhaf2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (153 aa)
mdkUncharacterized protein. (142 aa)
Dkk3.SDickkopf_N domain-containing protein. (257 aa)
A0A1L8GEK8EF-hand domain-containing protein. (366 aa)
A0A1L8GER2Uncharacterized protein; Belongs to the peptidase C19 family. (941 aa)
A0A1L8GH13Uncharacterized protein. (198 aa)
sox10HMG box domain-containing protein. (438 aa)
A0A1L8GHR8Uncharacterized protein. (300 aa)
A0A1L8GIG9Dickkopf_N domain-containing protein. (407 aa)
Mdk.LUncharacterized protein. (173 aa)
frmd8FERM domain-containing protein. (452 aa)
nkd1EF-hand domain-containing protein. (453 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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