STRINGSTRING
Jup.S Jup.S A0A1L8EL45 A0A1L8EL45 A0A1L8EMB9 A0A1L8EMB9 myocd myocd gper1 gper1 A0A1L8ESG1 A0A1L8ESG1 Myocd.L Myocd.L igfbp5-2 igfbp5-2 gper1-2 gper1-2 Setd3.S Setd3.S mymk mymk A0A1L8F1J8 A0A1L8F1J8 A0A1L8F437 A0A1L8F437 Casq1.S Casq1.S rusc1 rusc1 mymk-2 mymk-2 A0A1L8F6T4 A0A1L8F6T4 setd3 setd3 Akap6.L Akap6.L A0A1L8FCN2 A0A1L8FCN2 A0A1L8FDB0 A0A1L8FDB0 A0A1L8FDM1 A0A1L8FDM1 Glrx3.S Glrx3.S Errfi1.S Errfi1.S rnf207 rnf207 Tnnt1.S Tnnt1.S gsk3a gsk3a A0A1L8FI34 A0A1L8FI34 tnfrsf1a tnfrsf1a glrx3 glrx3 Rnf207.L Rnf207.L A0A1L8FMX8 A0A1L8FMX8 Tnni3.L Tnni3.L A0A1L8FN20 A0A1L8FN20 Sri.S Sri.S A0A1L8FRB1 A0A1L8FRB1 Ctdp1.S Ctdp1.S Rock1.S Rock1.S fbxo32 fbxo32 A0A1L8FW85 A0A1L8FW85 Fcp1 Fcp1 Rock1.L Rock1.L A0A1L8FZY4 A0A1L8FZY4 srf srf pln pln A0A1L8G3G8 A0A1L8G3G8 A0A1L8G633 A0A1L8G633 srf-2 srf-2 pln-2 pln-2 A0A1L8G9L8 A0A1L8G9L8 A0A1L8GC32 A0A1L8GC32 A0A1L8GD44 A0A1L8GD44 A0A1L8GDD4 A0A1L8GDD4 Tnnt3.L Tnnt3.L A0A1L8GE00 A0A1L8GE00 A0A1L8GFE7 A0A1L8GFE7 Tnnc1.L Tnnc1.L lmcd1 lmcd1 A0A1L8GI68 A0A1L8GI68 A0A1L8GI80 A0A1L8GI80 TNNT3 TNNT3 kcnq1 kcnq1 Tnni3k.L Tnni3k.L A0A1L8GNL6 A0A1L8GNL6 A0A1L8GPB5 A0A1L8GPB5 lmcd1-2 lmcd1-2 cav3.1 cav3.1 A0A1L8GQ67 A0A1L8GQ67 A0A1L8GQA4 A0A1L8GQA4 A0A1L8GQF7 A0A1L8GQF7 chrm2 chrm2 A0A1L8GQW8 A0A1L8GQW8 anxa6 anxa6 adra2b adra2b A0A1L8GS75 A0A1L8GS75 A0A1L8GS90 A0A1L8GS90 kbtbd13 kbtbd13 A0A1L8GU64 A0A1L8GU64 A0A1L8GU82 A0A1L8GU82 A0A1L8GUA0 A0A1L8GUA0 A0A1L8GUA6 A0A1L8GUA6 A0A1L8GUB9 A0A1L8GUB9 A0A1L8GVV7 A0A1L8GVV7 Pkp2.L Pkp2.L A0A1L8GW83 A0A1L8GW83 Anxa6.L Anxa6.L A0A1L8GXP7 A0A1L8GXP7 nkx2-5 nkx2-5 A0A1L8GYX0 A0A1L8GYX0 Kbtbd13.L Kbtbd13.L A0A1L8H1B6 A0A1L8H1B6 A0A1L8H1C8 A0A1L8H1C8 adra2b-2 adra2b-2 Stc1.L Stc1.L rangrf rangrf Tomm70.S Tomm70.S gja5 gja5 A0A1L8H5Q6 A0A1L8H5Q6 A0A1L8H5R2 A0A1L8H5R2 Pde9a.S Pde9a.S Myog.S Myog.S A0A1L8H700 A0A1L8H700 Slc9a1.S Slc9a1.S edn2 edn2 zc3h12a zc3h12a gtf2ird1 gtf2ird1 A0A1L8H9L9 A0A1L8H9L9 A0A1L8HBM0 A0A1L8HBM0 A0A1L8HBT3 A0A1L8HBT3 A0A1L8HBT4 A0A1L8HBT4 A0A1L8HBY8 A0A1L8HBY8 gja5-2 gja5-2 A0A1L8HE68 A0A1L8HE68 slc9a1 slc9a1 A0A1L8HEE4 A0A1L8HEE4 A0A1L8HEU2 A0A1L8HEU2 zc3h12a-2 zc3h12a-2 gtf2ird1-2 gtf2ird1-2 p2rx1 p2rx1 ankrd52 ankrd52 oxt oxt Adra2c.S Adra2c.S A0A1L8HL83 A0A1L8HL83 A0A1L8HLI5 A0A1L8HLI5 tacr3 tacr3 tbxa2r tbxa2r tmem38b tmem38b zdhhc21 zdhhc21 parp2 parp2 A0A1L8HRG6 A0A1L8HRG6 A0A1L8HRH1 A0A1L8HRH1 A0A1L8HRI7 A0A1L8HRI7 A0A1L8HRJ4 A0A1L8HRJ4 A0A1L8HRL3 A0A1L8HRL3 A0A1L8HRY9 A0A1L8HRY9 smad7 smad7 oxt-2 oxt-2 adra2c adra2c nmu nmu hand2 hand2 tacr3-2 tacr3-2 tbxa2r-2 tbxa2r-2 tmem38b-2 tmem38b-2 zdhhc21-2 zdhhc21-2 parp2-2 parp2-2 P2rx4.L P2rx4.L myog myog A0A1L8I125 A0A1L8I125 A0A1L8I156 A0A1L8I156 A0A1L8I2B6 A0A1L8I2B6 A0A1L8I2V3 A0A1L8I2V3 cmya5 cmya5 A0A310U0X3 A0A310U0X3 atp2a2 atp2a2 tnni1 tnni1 sri sri tnfrsf1a-2 tnfrsf1a-2 tnnc1 tnnc1 smad7-2 smad7-2 edn1 edn1 parp1 parp1 LOC495046 LOC495046 trim63 trim63 ucn1 ucn1 cav1a cav1a jup jup cav1 cav1 errfi1 errfi1 tnni1.2 tnni1.2 nkx2-5-2 nkx2-5-2 tnnc2 tnnc2 cav3.2 cav3.2 Cav-3 Cav-3 LOC397803 LOC397803
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Jup.SUncharacterized protein. (791 aa)
A0A1L8EL45Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1852 aa)
A0A1L8EMB9Uncharacterized protein. (293 aa)
myocdSAP domain-containing protein. (960 aa)
gper1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (361 aa)
A0A1L8ESG1Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1827 aa)
Myocd.LSAP domain-containing protein. (959 aa)
igfbp5-2Uncharacterized protein. (265 aa)
gper1-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (372 aa)
Setd3.SProtein-histidine N-methyltransferase. (725 aa)
mymkUncharacterized protein. (220 aa)
A0A1L8F1J8Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (672 aa)
A0A1L8F437Uncharacterized protein. (1652 aa)
Casq1.SCalsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (429 aa)
rusc1Uncharacterized protein. (1015 aa)
mymk-2Uncharacterized protein. (220 aa)
A0A1L8F6T4Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
setd3Protein-histidine N-methyltransferase. (582 aa)
Akap6.LUncharacterized protein. (1871 aa)
A0A1L8FCN2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (429 aa)
A0A1L8FDB0Mothers against decapentaplegic homolog. (514 aa)
A0A1L8FDM1G_PROTEIN_RECEP_F1_2 domain-containing protein. (453 aa)
Glrx3.SUncharacterized protein. (326 aa)
Errfi1.SInhibitor_Mig-6 domain-containing protein. (404 aa)
rnf207Uncharacterized protein. (639 aa)
Tnnt1.SUncharacterized protein. (334 aa)
gsk3aProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (424 aa)
A0A1L8FI34G_PROTEIN_RECEP_F1_2 domain-containing protein. (453 aa)
tnfrsf1aUncharacterized protein. (422 aa)
glrx3Uncharacterized protein. (326 aa)
Rnf207.LUncharacterized protein. (598 aa)
A0A1L8FMX8Uncharacterized protein. (266 aa)
Tnni3.LUncharacterized protein. (238 aa)
A0A1L8FN20Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
Sri.SUncharacterized protein. (280 aa)
A0A1L8FRB1ANK_REP_REGION domain-containing protein. (1053 aa)
Ctdp1.SRNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (977 aa)
Rock1.SRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1367 aa)
fbxo32Uncharacterized protein. (353 aa)
A0A1L8FW85ANK_REP_REGION domain-containing protein. (1052 aa)
Fcp1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (979 aa)
Rock1.LRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1360 aa)
A0A1L8FZY4Uncharacterized protein. (462 aa)
srfMADS-box domain-containing protein. (449 aa)
plnCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
A0A1L8G3G8Uncharacterized protein. (855 aa)
A0A1L8G633CRF domain-containing protein. (157 aa)
srf-2MADS-box domain-containing protein. (448 aa)
pln-2Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
A0A1L8G9L8Uncharacterized protein. (851 aa)
A0A1L8GC32Uncharacterized protein. (305 aa)
A0A1L8GD44Uncharacterized protein; Belongs to the potassium channel family. (637 aa)
A0A1L8GDD4Uncharacterized protein. (258 aa)
Tnnt3.LUncharacterized protein. (326 aa)
A0A1L8GE00Uncharacterized protein. (1294 aa)
A0A1L8GFE7Uncharacterized protein. (800 aa)
Tnnc1.LUncharacterized protein. (175 aa)
lmcd1Uncharacterized protein. (352 aa)
A0A1L8GI68Uncharacterized protein. (337 aa)
A0A1L8GI80Uncharacterized protein. (1175 aa)
TNNT3Uncharacterized protein. (495 aa)
kcnq1Uncharacterized protein; Belongs to the potassium channel family. (652 aa)
Tnni3k.LUncharacterized protein. (833 aa)
A0A1L8GNL6ATP_Ca_trans_C domain-containing protein. (180 aa)
A0A1L8GPB5Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
lmcd1-2Uncharacterized protein. (352 aa)
cav3.1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
A0A1L8GQ67Uncharacterized protein. (117 aa)
A0A1L8GQA4Uncharacterized protein. (760 aa)
A0A1L8GQF7ANK_REP_REGION domain-containing protein. (94 aa)
chrm2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (467 aa)
A0A1L8GQW8Uncharacterized protein; Belongs to the potassium channel family. (667 aa)
anxa6Annexin. (674 aa)
adra2bG_PROTEIN_RECEP_F1_2 domain-containing protein. (410 aa)
A0A1L8GS75G_PROTEIN_RECEP_F1_2 domain-containing protein. (489 aa)
A0A1L8GS90G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (406 aa)
kbtbd13BTB domain-containing protein. (466 aa)
A0A1L8GU64DHR-2 domain-containing protein; Belongs to the DOCK family. (518 aa)
A0A1L8GU82SH3 domain-containing protein. (220 aa)
A0A1L8GUA0Uncharacterized protein. (315 aa)
A0A1L8GUA6DHR-1 domain-containing protein; Belongs to the DOCK family. (633 aa)
A0A1L8GUB9DHR-2 domain-containing protein; Belongs to the DOCK family. (248 aa)
A0A1L8GVV7Uncharacterized protein. (114 aa)
Pkp2.LUncharacterized protein. (736 aa)
A0A1L8GW83Uncharacterized protein; Belongs to the potassium channel family. (604 aa)
Anxa6.LAnnexin. (673 aa)
A0A1L8GXP7Uncharacterized protein. (147 aa)
nkx2-5Homeobox domain-containing protein. (300 aa)
A0A1L8GYX0Uncharacterized protein; Belongs to the DOCK family. (1952 aa)
Kbtbd13.LUncharacterized protein. (432 aa)
A0A1L8H1B6G_PROTEIN_RECEP_F1_2 domain-containing protein. (489 aa)
A0A1L8H1C8G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (406 aa)
adra2b-2G_PROTEIN_RECEP_F1_2 domain-containing protein. (410 aa)
Stc1.LUncharacterized protein. (253 aa)
rangrfUncharacterized protein. (259 aa)
Tomm70.STPR_REGION domain-containing protein. (576 aa)
gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (360 aa)
A0A1L8H5Q6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
A0A1L8H5R2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (432 aa)
Pde9a.SPhosphodiesterase. (598 aa)
Myog.SBHLH domain-containing protein. (236 aa)
A0A1L8H700Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1209 aa)
Slc9a1.SSodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (774 aa)
edn2Uncharacterized protein. (169 aa)
zc3h12aC3H1-type domain-containing protein. (637 aa)
gtf2ird1Uncharacterized protein. (993 aa)
A0A1L8H9L9ANK_REP_REGION domain-containing protein. (1044 aa)
A0A1L8HBM0PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (321 aa)
A0A1L8HBT3Uncharacterized protein. (28 aa)
A0A1L8HBT4Protein kinase domain-containing protein. (64 aa)
A0A1L8HBY8Protein kinase domain-containing protein. (298 aa)
gja5-2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (364 aa)
A0A1L8HE68Uncharacterized protein. (161 aa)
slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (773 aa)
A0A1L8HEE4Uncharacterized protein. (356 aa)
A0A1L8HEU2Uncharacterized protein. (205 aa)
zc3h12a-2C3H1-type domain-containing protein. (644 aa)
gtf2ird1-2Uncharacterized protein. (941 aa)
p2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (412 aa)
ankrd52ANK_REP_REGION domain-containing protein. (1068 aa)
oxtUncharacterized protein; Belongs to the vasopressin/oxytocin family. (125 aa)
Adra2c.SG_PROTEIN_RECEP_F1_2 domain-containing protein. (442 aa)
A0A1L8HL83NMU domain-containing protein. (177 aa)
A0A1L8HLI5BHLH domain-containing protein. (272 aa)
tacr3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (431 aa)
tbxa2rG_PROTEIN_RECEP_F1_2 domain-containing protein. (371 aa)
tmem38bUncharacterized protein. (284 aa)
zdhhc21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (338 aa)
parp2Poly [ADP-ribose] polymerase. (742 aa)
A0A1L8HRG6Uncharacterized protein. (164 aa)
A0A1L8HRH1Uncharacterized protein. (814 aa)
A0A1L8HRI7Uncharacterized protein. (110 aa)
A0A1L8HRJ4Uncharacterized protein. (49 aa)
A0A1L8HRL3Uncharacterized protein. (316 aa)
A0A1L8HRY9Mothers against decapentaplegic homolog. (549 aa)
smad7Mothers against decapentaplegic homolog. (382 aa)
oxt-2Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (125 aa)
adra2cG_PROTEIN_RECEP_F1_2 domain-containing protein. (439 aa)
nmuNMU domain-containing protein. (186 aa)
hand2BHLH domain-containing protein. (210 aa)
tacr3-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (431 aa)
tbxa2r-2G_PROTEIN_RECEP_F1_2 domain-containing protein. (371 aa)
tmem38b-2Uncharacterized protein. (284 aa)
zdhhc21-2Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
parp2-2Poly [ADP-ribose] polymerase. (680 aa)
P2rx4.LUncharacterized protein. (154 aa)
myogMyogenin U1. (235 aa)
A0A1L8I125Uncharacterized protein. (141 aa)
A0A1L8I156Uncharacterized protein. (96 aa)
A0A1L8I2B6Uncharacterized protein. (868 aa)
A0A1L8I2V3Mothers against decapentaplegic homolog. (510 aa)
cmya5Uncharacterized protein. (1561 aa)
A0A310U0X3Uncharacterized protein. (73 aa)
atp2a2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
tnni1LOC100037198 protein. (187 aa)
sriLOC100037199 protein. (196 aa)
tnfrsf1a-2Tumor necrosis factor receptor 1. (412 aa)
tnnc1Cardiac troponin C. (161 aa)
smad7-2Mothers against decapentaplegic homolog. (382 aa)
edn1LOC100158354 protein. (221 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
LOC495046Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
trim63Rnf30-prov protein. (356 aa)
ucn1Urocortin 1. (158 aa)
cav1aCaveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
jupLOC398496 protein. (737 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
errfi1MGC68521 protein. (401 aa)
tnni1.2MGC64405 protein. (183 aa)
nkx2-5-2Nkx2.5 protein. (299 aa)
tnnc2MGC52923 protein. (161 aa)
cav3.2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
Cav-3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
LOC397803Cardiac troponin I. (244 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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