STRINGSTRING
Ccr7.S Ccr7.S A0A1L8EKQ1 A0A1L8EKQ1 A0A1L8EKQ5 A0A1L8EKQ5 Ikzf3.S Ikzf3.S A0A1L8EKZ0 A0A1L8EKZ0 jmjd6 jmjd6 nhej1 nhej1 fzd5 fzd5 A0A1L8EQ99 A0A1L8EQ99 A0A1L8EQA7 A0A1L8EQA7 Stat3.2.L Stat3.2.L stat3.1 stat3.1 Ikzf3.L Ikzf3.L med1l med1l A0A1L8ES01 A0A1L8ES01 tmem98 tmem98 A0A1L8ESG4 A0A1L8ESG4 A0A1L8ETL3 A0A1L8ETL3 jmjd6-2 jmjd6-2 A0A1L8EVP6 A0A1L8EVP6 itgb6 itgb6 sp3 sp3 A0A1L8EX32 A0A1L8EX32 A0A1L8EX74 A0A1L8EX74 A0A1L8EX75 A0A1L8EX75 Lfng.L Lfng.L A0A1L8EXY7 A0A1L8EXY7 armc5 armc5 hectd1 hectd1 Tyro3.S Tyro3.S jag2 jag2 A0A1L8EZY9 A0A1L8EZY9 zbtb1 zbtb1 bcl11b bcl11b A0A1L8F0F3 A0A1L8F0F3 A0A1L8F0K0 A0A1L8F0K0 Batf.S Batf.S A0A1L8F0V0 A0A1L8F0V0 tsc1 tsc1 A0A1L8F1D9 A0A1L8F1D9 abl1 abl1 Foxp3.S Foxp3.S sash3 sash3 Cd40lg.S Cd40lg.S tgfb1 tgfb1 axl axl gata1 gata1 A0A1L8F4K5 A0A1L8F4K5 sema4a sema4a A0A1L8F518 A0A1L8F518 Rorc.S Rorc.S gon4l gon4l nrarp nrarp tsc1-2 tsc1-2 Itm2a.L Itm2a.L cd40lg cd40lg A0A1L8F8T7 A0A1L8F8T7 axl-2 axl-2 tgfb1-2 tgfb1-2 batf batf TSHR TSHR bcl11b-2 bcl11b-2 jag2-2 jag2-2 A0A1L8FAA6 A0A1L8FAA6 psen1 psen1 hectd1-2 hectd1-2 dll4 dll4 Ripk3.S Ripk3.S A0A1L8FC93 A0A1L8FC93 A0A1L8FCF2 A0A1L8FCF2 Sema4a.L Sema4a.L A0A1L8FD41 A0A1L8FD41 Rorc.L Rorc.L gon4l-2 gon4l-2 A0A1L8FDY2 A0A1L8FDY2 A0A1L8FE12 A0A1L8FE12 A0A1L8FEE8 A0A1L8FEE8 Nkx2-3.S Nkx2-3.S clcf1 clcf1 Pou2af1.S Pou2af1.S cd3e cd3e Cd3g.S Cd3g.S cd79a cd79a Bax.L Bax.L A0A1L8FIL9 A0A1L8FIL9 A0A1L8FIN3 A0A1L8FIN3 A0A1L8FJ64 A0A1L8FJ64 Nkx2-3.L Nkx2-3.L clcf1-2 clcf1-2 A0A1L8FKW5 A0A1L8FKW5 cd3e-2 cd3e-2 Pou2af1.L Pou2af1.L cd79a-2 cd79a-2 Itgb8.S Itgb8.S A0A1L8FR84 A0A1L8FR84 A0A1L8FRF3 A0A1L8FRF3 Eomes.S Eomes.S Tgfbr2.S Tgfbr2.S Cmtm7.S Cmtm7.S gli3 gli3 Bcl2.S Bcl2.S A0A1L8FT23 A0A1L8FT23 lyn lyn Tpd52.S Tpd52.S ripk2 ripk2 Fzd8.L Fzd8.L A0A1L8FW11 A0A1L8FW11 itgb8 itgb8 A0A1L8FWF0 A0A1L8FWF0 tgfbr2 tgfbr2 gli3-2 gli3-2 ikzf1 ikzf1 Med1.L Med1.L ccr9 ccr9 A0A1L8FX19 A0A1L8FX19 A0A1L8FXP7 A0A1L8FXP7 A0A1L8FYE8 A0A1L8FYE8 lyn-2 lyn-2 A0A1L8FZ33 A0A1L8FZ33 Tpd52.L Tpd52.L cdh17 cdh17 ripk2-2 ripk2-2 A0A1L8FZS0 A0A1L8FZS0 srf srf A0A1L8G189 A0A1L8G189 batf3 batf3 Pax1.S Pax1.S dll1 dll1 Dock10.S Dock10.S rsad2 rsad2 batf3-2 batf3-2 A0A1L8G6C6 A0A1L8G6C6 msh2 msh2 srf-2 srf-2 mertk mertk A0A1L8G7G5 A0A1L8G7G5 Themis.L Themis.L A0A1L8G8T2 A0A1L8G8T2 A0A1L8G9F4 A0A1L8G9F4 A0A1L8GAE1 A0A1L8GAE1 A0A1L8GBG3 A0A1L8GBG3 rsad2-2 rsad2-2 Blk.L Blk.L rag2 rag2 Traf6.S Traf6.S rag1 rag1 cbfb cbfb A0A1L8GFI0 A0A1L8GFI0 Rc3h1.S Rc3h1.S abl2 abl2 A0A1L8GGJ1 A0A1L8GGJ1 A0A1L8GGQ9 A0A1L8GGQ9 ep300 ep300 Lgals1.S Lgals1.S dcaf1 dcaf1 Traf6.L Traf6.L rag1-2 rag1-2 A0A1L8GJL1 A0A1L8GJL1 fadd fadd tnfsf13b tnfsf13b c-Jun c-Jun lgals1.1 lgals1.1 dll1-2 dll1-2 lgals1.3 lgals1.3 lef1-2 lef1-2 itm2a itm2a pir pir ctnnb1-2 ctnnb1-2 dnajb9-2 dnajb9-2 anxa1.1-2 anxa1.1-2 cd74 cd74 irf1 irf1 tusc2-2 tusc2-2 mgc69520 mgc69520 stat5b stat5b lig4 lig4 anxa1.1 anxa1.1 cmtm7 cmtm7 gas6-2 gas6-2 ptpn2 ptpn2 zap70 zap70 anxa1.3 anxa1.3 ctnnb1 ctnnb1 fadd-2 fadd-2 cebpg cebpg lep-2 lep-2 gata3 gata3 X-Delta-2 X-Delta-2 Stat5a Stat5a gata1a-A gata1a-A xfz8 xfz8 lgalsvb-a lgalsvb-a LOC397855 LOC397855 sp3-2 sp3-2 tusc2 tusc2 sash3-2 sash3-2 ccr7 ccr7 LOC398065 LOC398065 A0A310UCY7 A0A310UCY7 Ikzf1.S Ikzf1.S G67.L G67.L malt1-2 malt1-2 A0A1L8I2P8 A0A1L8I2P8 ptger4-2 ptger4-2 Camk4.L Camk4.L A0A1L8HZL4 A0A1L8HZL4 psmb11 psmb11 syk syk A0A1L8HYC9 A0A1L8HYC9 A0A1L8HYA8 A0A1L8HYA8 A0A1L8HY95 A0A1L8HY95 stk11-2 stk11-2 A0A1L8HWG7 A0A1L8HWG7 Kit.L Kit.L rhoh-2 rhoh-2 A0A1L8HSZ2 A0A1L8HSZ2 A0A1L8HS54 A0A1L8HS54 malt1 malt1 A0A1L8HRT3 A0A1L8HRT3 ptger4 ptger4 A0A1L8HR34 A0A1L8HR34 Syk.S Syk.S anxa1.2 anxa1.2 A0A1L8HNH2 A0A1L8HNH2 stk11 stk11 lef1 lef1 Kit.S Kit.S rhoh rhoh A0A1L8HKJ9 A0A1L8HKJ9 A0A1L8HJ12 A0A1L8HJ12 A0A1L8HID3 A0A1L8HID3 Stat6.L Stat6.L Wnt1.L Wnt1.L A0A1L8HH85 A0A1L8HH85 Gpr18.L Gpr18.L gas6 gas6 A0A1L8HGR1 A0A1L8HGR1 il18r1 il18r1 Foxn1.L Foxn1.L gpr89b gpr89b A0A1L8HBZ9 A0A1L8HBZ9 pknox1-2 pknox1-2 A0A1L8HAR8 A0A1L8HAR8 A0A1L8HAQ5 A0A1L8HAQ5 A0A1L8HA03 A0A1L8HA03 wnt1 wnt1 A0A1L8H9R9 A0A1L8H9R9 A0A1L8H9B5 A0A1L8H9B5 A0A1L8H9B3 A0A1L8H9B3 Gpr18.S Gpr18.S A0A1L8H7W4 A0A1L8H7W4 Sox13.S Sox13.S pknox1 pknox1 rabl3 rabl3 Foxn1.S Foxn1.S A0A1L8H4Q1 A0A1L8H4Q1 Tp53.L Tp53.L A0A1L8H479 A0A1L8H479 rora-2 rora-2 Ncaph2.L Ncaph2.L A0A1L8GZW5 A0A1L8GZW5 lep lep Gata3.L Gata3.L prr7-2 prr7-2 Fnip1.L Fnip1.L itfg2 itfg2 fnip1 fnip1 Irf1.S Irf1.S prr7 prr7 dnajb9 dnajb9 ncaph2 ncaph2 A0A1L8GTG8 A0A1L8GTG8 rora rora Cd74.S Cd74.S A0A1L8GR26 A0A1L8GR26 IL12B IL12B braf braf fbxo7 fbxo7 Dcaf1.L Dcaf1.L lgals1.2 lgals1.2 A0A1L8GNW6 A0A1L8GNW6 ep300-2 ep300-2 A0A1L8GN98 A0A1L8GN98 Abl2.L Abl2.L Rc3h1.L Rc3h1.L A0A1L8GM23 A0A1L8GM23 Jun.L Jun.L A0A1L8GKL1 A0A1L8GKL1 cbfb-2 cbfb-2 CD79b.b CD79b.b A0A1L8EKH9 A0A1L8EKH9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ccr7.SG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (380 aa)
A0A1L8EKQ1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa)
A0A1L8EKQ5Uncharacterized protein. (534 aa)
Ikzf3.SUncharacterized protein. (511 aa)
A0A1L8EKZ0Uncharacterized protein. (226 aa)
jmjd6JmjC domain-containing protein. (403 aa)
nhej1Uncharacterized protein. (362 aa)
fzd5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
A0A1L8EQ99Fibronectin type-III domain-containing protein. (954 aa)
A0A1L8EQA7Fibronectin type-III domain-containing protein. (866 aa)
Stat3.2.LSignal transducer and activator of transcription. (760 aa)
stat3.1Signal transducer and activator of transcription. (769 aa)
Ikzf3.LUncharacterized protein. (513 aa)
med1lMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa)
A0A1L8ES01Uncharacterized protein. (552 aa)
tmem98Uncharacterized protein. (226 aa)
A0A1L8ESG4Ig-like domain-containing protein. (239 aa)
A0A1L8ETL3Carrier domain-containing protein. (2510 aa)
jmjd6-2JmjC domain-containing protein. (403 aa)
A0A1L8EVP6Uncharacterized protein. (289 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (780 aa)
sp3Uncharacterized protein. (717 aa)
A0A1L8EX32Nudix hydrolase domain-containing protein. (1441 aa)
A0A1L8EX74Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
A0A1L8EX75Uncharacterized protein. (1160 aa)
Lfng.LBeta-1,3-N-acetylglucosaminyltransferase. (373 aa)
A0A1L8EXY7Fibronectin type-III domain-containing protein. (903 aa)
armc5BTB domain-containing protein. (934 aa)
hectd1Uncharacterized protein. (2556 aa)
Tyro3.SUncharacterized protein. (832 aa)
jag2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1223 aa)
A0A1L8EZY9Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
zbtb1Uncharacterized protein. (695 aa)
bcl11bUncharacterized protein. (810 aa)
A0A1L8F0F3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (356 aa)
A0A1L8F0K0G_PROTEIN_RECEP_F1_2 domain-containing protein. (607 aa)
Batf.SBZIP domain-containing protein. (115 aa)
A0A1L8F0V0Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (650 aa)
tsc1Uncharacterized protein. (1104 aa)
A0A1L8F1D9Uncharacterized protein. (707 aa)
abl1Tyrosine-protein kinase. (1122 aa)
Foxp3.SUncharacterized protein. (429 aa)
sash3Uncharacterized protein. (391 aa)
Cd40lg.SCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (273 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
axlUncharacterized protein. (890 aa)
gata1Uncharacterized protein. (367 aa)
A0A1L8F4K5Tyrosine-protein kinase receptor. (864 aa)
sema4aSema domain-containing protein; Belongs to the semaphorin family. (742 aa)
A0A1L8F518Fibronectin type-III domain-containing protein. (433 aa)
Rorc.SUncharacterized protein. (465 aa)
gon4lUncharacterized protein. (1918 aa)
nrarpANK_REP_REGION domain-containing protein. (114 aa)
tsc1-2Uncharacterized protein. (1102 aa)
Itm2a.LBRICHOS domain-containing protein. (246 aa)
cd40lgTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (279 aa)
A0A1L8F8T7G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (343 aa)
axl-2Uncharacterized protein. (896 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
batfBZIP domain-containing protein. (115 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (760 aa)
bcl11b-2Uncharacterized protein. (809 aa)
jag2-2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1227 aa)
A0A1L8FAA6Uncharacterized protein. (694 aa)
psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
hectd1-2Uncharacterized protein. (2578 aa)
dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (675 aa)
Ripk3.SProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (425 aa)
A0A1L8FC93Tyrosine-protein kinase receptor. (804 aa)
A0A1L8FCF2Ig-like domain-containing protein. (352 aa)
Sema4a.LSema domain-containing protein; Belongs to the semaphorin family. (719 aa)
A0A1L8FD41Uncharacterized protein. (428 aa)
Rorc.LUncharacterized protein. (504 aa)
gon4l-2Uncharacterized protein. (1752 aa)
A0A1L8FDY2Ig-like domain-containing protein. (467 aa)
A0A1L8FE12Uncharacterized protein. (179 aa)
A0A1L8FEE8SH2 domain-containing protein. (549 aa)
Nkx2-3.SHomeobox domain-containing protein. (335 aa)
clcf1Uncharacterized protein. (223 aa)
Pou2af1.SUncharacterized protein. (257 aa)
cd3eIGc2 domain-containing protein. (182 aa)
Cd3g.SIg-like domain-containing protein. (217 aa)
cd79aIg-like domain-containing protein. (207 aa)
Bax.LUncharacterized protein. (221 aa)
A0A1L8FIL9Ig-like domain-containing protein. (491 aa)
A0A1L8FIN3Uncharacterized protein. (306 aa)
A0A1L8FJ64SH2 domain-containing protein. (678 aa)
Nkx2-3.LHomeobox domain-containing protein. (331 aa)
clcf1-2Uncharacterized protein. (223 aa)
A0A1L8FKW5Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2533 aa)
cd3e-2Uncharacterized protein. (179 aa)
Pou2af1.LUncharacterized protein. (267 aa)
cd79a-2Ig-like domain-containing protein. (228 aa)
Itgb8.SIntegrin beta; Belongs to the integrin beta chain family. (726 aa)
A0A1L8FR84Uncharacterized protein. (220 aa)
A0A1L8FRF3TBD domain-containing protein. (382 aa)
Eomes.ST-box_assoc domain-containing protein. (668 aa)
Tgfbr2.SSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (800 aa)
Cmtm7.SMARVEL domain-containing protein. (164 aa)
gli3Uncharacterized protein. (1565 aa)
Bcl2.SBH4_2 domain-containing protein. (253 aa)
A0A1L8FT23HMG box domain-containing protein. (489 aa)
lynTyrosine-protein kinase. (508 aa)
Tpd52.SUncharacterized protein. (219 aa)
ripk2Uncharacterized protein. (550 aa)
Fzd8.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
A0A1L8FW11Uncharacterized protein. (139 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (809 aa)
A0A1L8FWF0TBD domain-containing protein. (207 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (795 aa)
gli3-2Uncharacterized protein. (1568 aa)
ikzf1Uncharacterized protein. (567 aa)
Med1.LMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (649 aa)
ccr9G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (366 aa)
A0A1L8FX19Uncharacterized protein. (68 aa)
A0A1L8FXP7BH4_2 domain-containing protein. (300 aa)
A0A1L8FYE8Tyrosine-protein phosphatase non-receptor type. (462 aa)
lyn-2Tyrosine-protein kinase. (508 aa)
A0A1L8FZ33HMG box domain-containing protein. (537 aa)
Tpd52.LUncharacterized protein. (219 aa)
cdh17Uncharacterized protein. (827 aa)
ripk2-2Uncharacterized protein. (545 aa)
A0A1L8FZS0DC_STAMP domain-containing protein. (493 aa)
srfMADS-box domain-containing protein. (449 aa)
A0A1L8G189Homeobox domain-containing protein. (381 aa)
batf3BZIP domain-containing protein. (127 aa)
Pax1.SPaired domain-containing protein. (449 aa)
dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
Dock10.SUncharacterized protein; Belongs to the DOCK family. (2159 aa)
rsad2Elp3 domain-containing protein. (350 aa)
batf3-2BZIP domain-containing protein. (127 aa)
A0A1L8G6C6Homeobox domain-containing protein. (387 aa)
msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (932 aa)
srf-2MADS-box domain-containing protein. (448 aa)
mertkUncharacterized protein. (979 aa)
A0A1L8G7G5Paired domain-containing protein. (437 aa)
Themis.LUncharacterized protein. (572 aa)
A0A1L8G8T2SEFIR domain-containing protein. (397 aa)
A0A1L8G9F4Autophagy protein 5; Involved in autophagic vesicle formation. (334 aa)
A0A1L8GAE1Uncharacterized protein; Belongs to the DOCK family. (2181 aa)
A0A1L8GBG3Uncharacterized protein. (431 aa)
rsad2-2Elp3 domain-containing protein. (363 aa)
Blk.LTyrosine-protein kinase. (497 aa)
rag2RAG2_PHD domain-containing protein. (520 aa)
Traf6.STNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1045 aa)
cbfbUncharacterized protein. (185 aa)
A0A1L8GFI0Uncharacterized protein. (848 aa)
Rc3h1.SUncharacterized protein. (1138 aa)
abl2Tyrosine-protein kinase. (1102 aa)
A0A1L8GGJ1Uncharacterized protein. (1173 aa)
A0A1L8GGQ9BZIP domain-containing protein. (137 aa)
ep300Uncharacterized protein. (2495 aa)
Lgals1.SGalectin. (134 aa)
dcaf1LisH domain-containing protein. (1485 aa)
Traf6.LTNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
rag1-2V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1045 aa)
A0A1L8GJL1BZIP domain-containing protein. (125 aa)
faddUncharacterized protein. (188 aa)
tnfsf13bBAFF; Belongs to the tumor necrosis factor family. (266 aa)
c-JunC-Jun protein; Belongs to the bZIP family. (312 aa)
lgals1.1Galectin. (134 aa)
dll1-2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
lgals1.3Galectin. (135 aa)
lef1-2Lymphoid enhancer factor XLEF-1. (372 aa)
itm2aMGC52743 protein. (247 aa)
pirMGC53094 protein; Belongs to the pirin family. (290 aa)
ctnnb1-2Ctnnb1-prov protein. (781 aa)
dnajb9-2Dnajb9-prov protein. (221 aa)
anxa1.1-2Annexin. (343 aa)
cd74MGC68635 protein. (293 aa)
irf1Interferon regulatory factor. (298 aa)
tusc2-2MGC68809 protein. (106 aa)
mgc69520MGC81231 protein; Belongs to the G-protein coupled receptor 1 family. (345 aa)
stat5bSignal transducer and activator of transcription. (781 aa)
lig4DNA ligase. (911 aa)
anxa1.1Annexin. (343 aa)
cmtm7Cklfsf7-prov protein. (164 aa)
gas6-2Gas6-prov protein. (669 aa)
ptpn2Tyrosine-protein phosphatase non-receptor type. (468 aa)
zap70Tyrosine-protein kinase. (617 aa)
anxa1.3Annexin. (363 aa)
ctnnb1Beta-catenin protein. (781 aa)
fadd-2Fas-associating death domain-containing protein. (188 aa)
cebpgMGC114733 protein. (143 aa)
lep-2Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
gata3XGATA-3 protein. (435 aa)
X-Delta-2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa)
Stat5aSignal transducer and activator of transcription. (781 aa)
gata1a-AGATA binding factor-1. (359 aa)
xfz8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
lgalsvb-aGalectin. (135 aa)
LOC397855Beta-1,3-N-acetylglucosaminyltransferase. (375 aa)
sp3-2LOC100037013 protein. (724 aa)
tusc2LOC100137709 protein. (106 aa)
sash3-2LOC100049772 protein. (386 aa)
ccr7LOC100036961 protein; Belongs to the G-protein coupled receptor 1 family. (358 aa)
LOC398065LOC398065 protein. (666 aa)
A0A310UCY7BHLH domain-containing protein. (333 aa)
Ikzf1.SC2H2-type domain-containing protein. (273 aa)
G67.LUncharacterized protein. (718 aa)
malt1-2Uncharacterized protein. (796 aa)
A0A1L8I2P8Uncharacterized protein. (473 aa)
ptger4-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
Camk4.LProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (388 aa)
A0A1L8HZL4Protein kinase domain-containing protein. (523 aa)
psmb11Proteasome subunit beta. (276 aa)
sykTyrosine-protein kinase. (605 aa)
A0A1L8HYC9Annexin. (242 aa)
A0A1L8HYA8BZIP domain-containing protein. (436 aa)
A0A1L8HY95Annexin. (338 aa)
stk11-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
A0A1L8HWG7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (383 aa)
Kit.LMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
rhoh-2Uncharacterized protein. (190 aa)
A0A1L8HSZ2Ig-like domain-containing protein. (235 aa)
A0A1L8HS54SCY domain-containing protein. (97 aa)
malt1Uncharacterized protein. (800 aa)
A0A1L8HRT3FN3_7 domain-containing protein. (446 aa)
ptger4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (476 aa)
A0A1L8HR34Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (387 aa)
Syk.STyrosine-protein kinase. (632 aa)
anxa1.2Annexin. (338 aa)
A0A1L8HNH2Tyrosine-protein kinase. (608 aa)
stk11Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
lef1HMG box domain-containing protein. (372 aa)
Kit.SMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
rhohUncharacterized protein. (191 aa)
A0A1L8HKJ9Ig-like domain-containing protein. (240 aa)
A0A1L8HJ12Uncharacterized protein. (781 aa)
A0A1L8HID3KRAP_IP3R_bind domain-containing protein. (255 aa)
Stat6.LSignal transducer and activator of transcription. (791 aa)
Wnt1.LProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
A0A1L8HH85G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (360 aa)
Gpr18.LG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (331 aa)
gas6Uncharacterized protein. (668 aa)
A0A1L8HGR1Uncharacterized protein. (564 aa)
il18r1Uncharacterized protein. (558 aa)
Foxn1.LFork-head domain-containing protein. (667 aa)
gpr89bUncharacterized protein. (455 aa)
A0A1L8HBZ9Uncharacterized protein. (242 aa)
pknox1-2Homeobox domain-containing protein. (428 aa)
A0A1L8HAR8Uncharacterized protein. (139 aa)
A0A1L8HAQ5Uncharacterized protein. (779 aa)
A0A1L8HA03KRAP_IP3R_bind domain-containing protein. (256 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
A0A1L8H9R9Signal transducer and activator of transcription. (743 aa)
A0A1L8H9B5Uncharacterized protein. (111 aa)
A0A1L8H9B3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (360 aa)
Gpr18.SG_PROTEIN_RECEP_F1_2 domain-containing protein. (330 aa)
A0A1L8H7W4Uncharacterized protein. (139 aa)
Sox13.SHMG box domain-containing protein. (567 aa)
pknox1Homeobox domain-containing protein. (427 aa)
rabl3Uncharacterized protein. (235 aa)
Foxn1.SFork-head domain-containing protein. (646 aa)
A0A1L8H4Q1Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (200 aa)
Tp53.LP53 domain-containing protein. (137 aa)
A0A1L8H479Uncharacterized protein. (274 aa)
rora-2Uncharacterized protein. (464 aa)
Ncaph2.LUncharacterized protein. (624 aa)
A0A1L8GZW5Uncharacterized protein. (633 aa)
lepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
Gata3.LUncharacterized protein. (454 aa)
prr7-2Uncharacterized protein. (258 aa)
Fnip1.LUDENN FNIP1/2-type domain-containing protein. (1124 aa)
itfg2Uncharacterized protein. (444 aa)
fnip1UDENN FNIP1/2-type domain-containing protein. (1157 aa)
Irf1.SInterferon regulatory factor. (345 aa)
prr7Uncharacterized protein. (262 aa)
dnajb9J domain-containing protein. (221 aa)
ncaph2Uncharacterized protein. (620 aa)
A0A1L8GTG8Uncharacterized protein. (641 aa)
roraUncharacterized protein. (461 aa)
Cd74.SThyroglobulin type-1 domain-containing protein. (302 aa)
A0A1L8GR26HMG box domain-containing protein. (487 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (316 aa)
brafUncharacterized protein. (802 aa)
fbxo7F-box domain-containing protein. (500 aa)
Dcaf1.LLisH domain-containing protein. (1521 aa)
lgals1.2Galectin. (135 aa)
A0A1L8GNW6Galectin. (139 aa)
ep300-2Uncharacterized protein. (2492 aa)
A0A1L8GN98Uncharacterized protein. (1290 aa)
Abl2.LTyrosine-protein kinase. (1102 aa)
Rc3h1.LUncharacterized protein. (1114 aa)
A0A1L8GM23Uncharacterized protein. (1150 aa)
Jun.LBZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
A0A1L8GKL1Uncharacterized protein. (495 aa)
cbfb-2Uncharacterized protein. (185 aa)
CD79b.bCD79b.b. (224 aa)
A0A1L8EKH9STAT_int domain-containing protein. (635 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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