25 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Il1b.L	Interleukin-1. (145 aa)
	cldn5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)
	cldn5-2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)
	tnf	TNF_2 domain-containing protein. (227 aa)
	F11r.S	Uncharacterized protein. (289 aa)
	f11r	LOC398627 protein. (291 aa)
	il1b-A	Interleukin-1; Belongs to the IL-1 family. (283 aa)
	tnfrsf1a-2	Tumor necrosis factor receptor 1. (412 aa)
	tnf-2	Tumor necrosis factor alpha. (225 aa)
	s1pr3-2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	zdhhc21-2	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
	add1-2	Aldolase_II domain-containing protein. (843 aa)
	s1pr3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	zdhhc21	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (338 aa)
	add1	Aldolase_II domain-containing protein. (856 aa)
	ikbkb	Uncharacterized protein. (769 aa)
	A0A1L8H1M9	Interleukin-1. (282 aa)
	Rock1.S	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1367 aa)
	cdh5-2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (775 aa)
	cdh5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (774 aa)
	Rock2.L	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1373 aa)
	A0A1L8GB68	Uncharacterized protein. (456 aa)
	rock2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1399 aa)
	Proc.S	Uncharacterized protein. (455 aa)
	Rock1.L	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1360 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8H1M9	ikbkb	A0A1L8H1M9	A0A1L8H261	Interleukin-1.	Uncharacterized protein.	0.462
A0A1L8H1M9	tnf	A0A1L8H1M9	A0A1L8F3P0	Interleukin-1.	TNF_2 domain-containing protein.	0.622
A0A1L8H1M9	tnf-2	A0A1L8H1M9	A9CPG2	Interleukin-1.	Tumor necrosis factor alpha.	0.808
A0A1L8H1M9	tnfrsf1a-2	A0A1L8H1M9	A9CPG4	Interleukin-1.	Tumor necrosis factor receptor 1.	0.644
F11r.S	cdh5	A0A1L8F5C9	A0A1L8GEW5	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.650
F11r.S	cdh5-2	A0A1L8F5C9	A0A1L8GKR1	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.650
F11r.S	cldn5	A0A1L8F5C9	Q6GNW1	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.853
F11r.S	cldn5-2	A0A1L8F5C9	Q6PA22	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.853
F11r.S	f11r	A0A1L8F5C9	Q2VPP6	Uncharacterized protein.	LOC398627 protein.	0.901
Il1b.L	ikbkb	A0A1L8H1M6	A0A1L8H261	Interleukin-1.	Uncharacterized protein.	0.668
Il1b.L	il1b-A	A0A1L8H1M6	B7ZSG9	Interleukin-1.	Interleukin-1; Belongs to the IL-1 family.	0.901
Il1b.L	tnf	A0A1L8H1M6	A0A1L8F3P0	Interleukin-1.	TNF_2 domain-containing protein.	0.860
Il1b.L	tnf-2	A0A1L8H1M6	A9CPG2	Interleukin-1.	Tumor necrosis factor alpha.	0.930
Il1b.L	tnfrsf1a-2	A0A1L8H1M6	A9CPG4	Interleukin-1.	Tumor necrosis factor receptor 1.	0.795
Rock1.L	Rock1.S	A0A1L8FYP1	A0A1L8FSV4	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.900
Rock1.L	Rock2.L	A0A1L8FYP1	A0A1L8GBJ7	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.805
Rock1.L	rock2	A0A1L8FYP1	A0A1L8G5H9	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.805
Rock1.S	Rock1.L	A0A1L8FSV4	A0A1L8FYP1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.900
Rock1.S	Rock2.L	A0A1L8FSV4	A0A1L8GBJ7	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.805
Rock1.S	rock2	A0A1L8FSV4	A0A1L8G5H9	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.805