97 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ino80d	Uncharacterized protein. (1025 aa)
	parn	R3H domain-containing protein. (632 aa)
	Xrcc5.L	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (726 aa)
	Ino80d.L	Uncharacterized protein. (1025 aa)
	A0A1L8EXH6	Fibronectin type-III domain-containing protein. (730 aa)
	Parn.L	R3H domain-containing protein. (631 aa)
	slx4	BTB domain-containing protein. (1773 aa)
	A0A1L8F2G2	PHD-type domain-containing protein. (1187 aa)
	ppp1r10	Uncharacterized protein. (819 aa)
	setdb1	Uncharacterized protein. (1290 aa)
	A0A1L8F4X5	Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (299 aa)
	A0A1L8F4Y5	T-complex protein 1 subunit gamma. (508 aa)
	Dkc1.L	PUA domain-containing protein. (558 aa)
	atrx	Uncharacterized protein. (2276 aa)
	ppp1r10-2	Uncharacterized protein. (843 aa)
	ino80	Uncharacterized protein. (1539 aa)
	Setdb1.L	Uncharacterized protein. (1343 aa)
	Ncapd2.S	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1358 aa)
	tnks2	Poly [ADP-ribose] polymerase. (1165 aa)
	A0A1L8FGQ7	Uncharacterized protein. (250 aa)
	A0A1L8FH58	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (47 aa)
	A0A1L8FH67	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (122 aa)
	A0A1L8FH77	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (108 aa)
	A0A1L8FH84	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (54 aa)
	pnkp	FHA_2 domain-containing protein. (594 aa)
	fbxo42	F-box domain-containing protein. (690 aa)
	A0A1L8FJB7	Uncharacterized protein. (1021 aa)
	ercc1	Uncharacterized protein. (297 aa)
	A0A1L8FL85	NFRKB_winged domain-containing protein. (1263 aa)
	A0A1L8FMY4	Uncharacterized protein. (267 aa)
	fbxo42-2	F-box domain-containing protein. (690 aa)
	A0A1L8FPM5	Uncharacterized protein. (363 aa)
	A0A1L8FS70	Uncharacterized protein. (704 aa)
	A0A1L8FXS7	Uncharacterized protein. (705 aa)
	Nsmce2.L	SP-RING-type domain-containing protein. (238 aa)
	A0A1L8G2F3	Protein kinase domain-containing protein. (1486 aa)
	dhx36	Uncharacterized protein. (977 aa)
	A0A1L8G7B8	Uncharacterized protein. (306 aa)
	dhx36-2	Uncharacterized protein. (1000 aa)
	Atr.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa)
	Smc4.L	Structural maintenance of chromosomes protein. (1299 aa)
	fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa)
	Cdt1.S	CDT1 domain-containing protein. (615 aa)
	atf7ip	Fibronectin type-III domain-containing protein. (1262 aa)
	uchl5	Ubiquitin carboxyl-terminal hydrolase. (329 aa)
	tpr	TPR_MLP1_2 domain-containing protein. (2321 aa)
	fen1-2	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa)
	atf7ip-2	Fibronectin type-III domain-containing protein. (1254 aa)
	Uchl5.L	Ubiquitin carboxyl-terminal hydrolase. (329 aa)
	A0A1L8GNN2	Uncharacterized protein. (423 aa)
	ruvbl1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
	A0A1L8GRE9	Protein kinase domain-containing protein. (455 aa)
	Ncaph.S	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (700 aa)
	rad50	Zinc-hook domain-containing protein. (1311 aa)
	Dnmt1.S	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1492 aa)
	A0A1L8GW57	Uncharacterized protein. (1847 aa)
	Ddx11.L	Helicase ATP-binding domain-containing protein. (898 aa)
	rad50-2	Zinc-hook domain-containing protein. (1312 aa)
	cct2	Uncharacterized protein. (535 aa)
	pphln1-2	Uncharacterized protein. (345 aa)
	Pot1.L	Telo_bind domain-containing protein. (621 aa)
	A0A1L8H1M8	Uncharacterized protein. (638 aa)
	Map2k7.S	Protein kinase domain-containing protein. (489 aa)
	Dnmt1.L	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1488 aa)
	Setdb2.S	Uncharacterized protein. (702 aa)
	mphosph8	Uncharacterized protein. (834 aa)
	numa1	Uncharacterized protein. (2302 aa)
	mphosph8-2	Uncharacterized protein. (847 aa)
	numa1-2	Uncharacterized protein. (2309 aa)
	tnks	Poly [ADP-ribose] polymerase. (1298 aa)
	smc5	AAA_15 domain-containing protein. (1063 aa)
	morc2	CW-type domain-containing protein. (1027 aa)
	mapkapk5	Protein kinase domain-containing protein. (484 aa)
	Ncapg.L	Cnd3 domain-containing protein. (1035 aa)
	naf1	Uncharacterized protein. (492 aa)
	smc2	Structural maintenance of chromosomes protein. (1202 aa)
	morc2-2	CW-type domain-containing protein. (1028 aa)
	mapkapk5-2	Protein kinase domain-containing protein. (484 aa)
	slf1	ANK_REP_REGION domain-containing protein. (904 aa)
	Cct5.S	Uncharacterized protein. (579 aa)
	A0A310U7K3	ANK_REP_REGION domain-containing protein. (486 aa)
	Gnl3.L	CP-type G domain-containing protein. (570 aa)
	h2afy	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (369 aa)
	LOC100037190	LOC100037190 protein. (331 aa)
	LOC100049093	LOC100049093 protein. (452 aa)
	fbxo4	LOC100158284 protein. (384 aa)
	ruvbl2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (462 aa)
	cct4	T-complex protein 1 subunit delta. (541 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	lig4	DNA ligase. (911 aa)
	cct4-2	T-complex protein 1 subunit delta. (539 aa)
	sirt6	MGC82564 protein. (331 aa)
	ruvbl1-2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
	mcrs1	Mcrs1-prov protein. (453 aa)
	ctnnb1-2	Ctnnb1-prov protein. (781 aa)
	cct2-2	Cct2-prov protein. (535 aa)
	Nek2	Nek2A. (442 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EXH6	Setdb1.L	A0A1L8EXH6	A0A1L8FBV0	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.909
A0A1L8EXH6	Setdb2.S	A0A1L8EXH6	A0A1L8HAK7	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.888
A0A1L8EXH6	setdb1	A0A1L8EXH6	A0A1L8F4F5	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.909
A0A1L8F2G2	A0A1L8FL85	A0A1L8F2G2	A0A1L8FL85	PHD-type domain-containing protein.	NFRKB_winged domain-containing protein.	0.457
A0A1L8F2G2	Pot1.L	A0A1L8F2G2	A0A1L8GZ08	PHD-type domain-containing protein.	Telo_bind domain-containing protein.	0.557
A0A1L8F2G2	Xrcc5.L	A0A1L8F2G2	A0A1L8EVE5	PHD-type domain-containing protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.420
A0A1L8F2G2	h2afy	A0A1L8F2G2	A1L2I5	PHD-type domain-containing protein.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.437
A0A1L8F2G2	mphosph8	A0A1L8F2G2	A0A1L8HAZ2	PHD-type domain-containing protein.	Uncharacterized protein.	0.488
A0A1L8F2G2	mphosph8-2	A0A1L8F2G2	A0A1L8HJ56	PHD-type domain-containing protein.	Uncharacterized protein.	0.488
A0A1L8F2G2	ruvbl1	A0A1L8F2G2	A0A1L8GPP7	PHD-type domain-containing protein.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.577
A0A1L8F2G2	ruvbl1-2	A0A1L8F2G2	Q6GR29	PHD-type domain-containing protein.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.577
A0A1L8F2G2	smc5	A0A1L8F2G2	A0A1L8HP39	PHD-type domain-containing protein.	AAA_15 domain-containing protein.	0.594
A0A1L8F4X5	Cct5.S	A0A1L8F4X5	A0A310U2H2	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	Uncharacterized protein.	0.999
A0A1L8F4X5	cct2	A0A1L8F4X5	A0A1L8GYM0	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	Uncharacterized protein.	0.996
A0A1L8F4X5	cct2-2	A0A1L8F4X5	Q8AVB7	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	Cct2-prov protein.	0.996
A0A1L8F4X5	cct4	A0A1L8F4X5	Q5XGW4	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	T-complex protein 1 subunit delta.	0.996
A0A1L8F4X5	cct4-2	A0A1L8F4X5	Q6GN66	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	T-complex protein 1 subunit delta.	0.996
A0A1L8F4Y5	Cct5.S	A0A1L8F4Y5	A0A310U2H2	T-complex protein 1 subunit gamma.	Uncharacterized protein.	0.999
A0A1L8F4Y5	cct2	A0A1L8F4Y5	A0A1L8GYM0	T-complex protein 1 subunit gamma.	Uncharacterized protein.	0.996
A0A1L8F4Y5	cct2-2	A0A1L8F4Y5	Q8AVB7	T-complex protein 1 subunit gamma.	Cct2-prov protein.	0.996