(64 nodes) Lamellipodium network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dusp22a	MGC82394 protein. (209 aa)
	ppp1r9b	PDZ domain-containing protein. (748 aa)
	A0A1L8EL09	Abi_HHR domain-containing protein. (315 aa)
	Gcg2	Uncharacterized protein. (266 aa)
	ppp1r9al	Uncharacterized protein. (1315 aa)
	abi3	Abi_HHR domain-containing protein. (343 aa)
	ppp1r9b-2	PDZ domain-containing protein. (748 aa)
	Gcg.L	Uncharacterized protein. (266 aa)
	Fap.L	DPPIV_N domain-containing protein. (480 aa)
	A0A1L8EW16	Uncharacterized protein. (70 aa)
	A0A1L8EW23	Peptidase_S9 domain-containing protein. (35 aa)
	Dpp4.L	Uncharacterized protein; Belongs to the peptidase S9B family. (811 aa)
	A0A1L8EW78	Peptidase_S9 domain-containing protein. (135 aa)
	A0A1L8EW81	Uncharacterized protein. (1348 aa)
	A0A1L8EX39	Uncharacterized protein. (1637 aa)
	A0A1L8F066	WH1 domain-containing protein. (709 aa)
	A0A1L8F093	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1684 aa)
	fgd1	Uncharacterized protein. (867 aa)
	A0A1L8F3F3	WH1 domain-containing protein. (319 aa)
	Vasp.L	WH1 domain-containing protein. (386 aa)
	evl	WH1 domain-containing protein. (713 aa)
	cdc42bpb	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1731 aa)
	hax1	Uncharacterized protein. (284 aa)
	A0A1L8FET5	Phosphoinositide phospholipase C. (1716 aa)
	A0A1L8FFC5	Uncharacterized protein. (292 aa)
	G50	Uncharacterized protein. (980 aa)
	A0A1L8FI80	Uncharacterized protein. (462 aa)
	A0A1L8FJQ6	Uncharacterized protein. (2292 aa)
	A0A1L8FKR9	VWFA domain-containing protein. (210 aa)
	Epha2.L	Uncharacterized protein. (948 aa)
	A0A1L8FQZ9	Uncharacterized protein. (1119 aa)
	slc39a6	Uncharacterized protein. (653 aa)
	ppp1r9a	Uncharacterized protein. (1120 aa)
	A0A1L8FXR1	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (209 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	A0A1L8G5B3	PID domain-containing protein. (180 aa)
	fam89a-2	Uncharacterized protein. (166 aa)
	Cfl1.L	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (292 aa)
	Fgd4.S	Uncharacterized protein. (758 aa)
	antxr1	VWFA domain-containing protein. (566 aa)
	fgd6	Uncharacterized protein. (1343 aa)
	A0A1L8GV78	Uncharacterized protein. (831 aa)
	Fgd4.L	Uncharacterized protein. (822 aa)
	A0A1L8GXR8	Uncharacterized protein. (664 aa)
	A0A1L8GYD0	Uncharacterized protein. (1340 aa)
	antxr1-2	VWFA domain-containing protein. (566 aa)
	phactr4	Phosphatase and actin regulator. (694 aa)
	Epac	Uncharacterized protein. (896 aa)
	phactr4-2	Phosphatase and actin regulator. (709 aa)
	Rapgef3.L	Uncharacterized protein. (897 aa)
	apbb1	Uncharacterized protein. (650 aa)
	A0A1L8HL51	Uncharacterized protein. (757 aa)
	Sh3rf1.S	Uncharacterized protein. (839 aa)
	Unc5c.S	Uncharacterized protein. (912 aa)
	tesc	EF-hand domain-containing protein. (214 aa)
	A0A1L8HTM4	Uncharacterized protein. (730 aa)
	sh3rf1	Uncharacterized protein. (874 aa)
	Unc5c.L	Uncharacterized protein. (929 aa)
	tesc-2	EF-hand domain-containing protein. (214 aa)
	A0A310TLQ6	Protein kinase domain-containing protein. (82 aa)
	A0A310TN06	Uncharacterized protein. (354 aa)
	cib1	LOC496348 protein. (190 aa)
	cib1-2	LOC495358 protein. (190 aa)
	dpp4	LOC397888 protein; Belongs to the peptidase S9B family. (737 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EW16	Dpp4.L	A0A1L8EW16	A0A1L8EW34	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase S9B family.	0.676
A0A1L8EW16	dpp4	A0A1L8EW16	Q641D6	Uncharacterized protein.	LOC397888 protein; Belongs to the peptidase S9B family.	0.676
A0A1L8EW78	Fap.L	A0A1L8EW78	A0A1L8EW08	Peptidase_S9 domain-containing protein.	DPPIV_N domain-containing protein.	0.491
A0A1L8F066	A0A1L8F3F3	A0A1L8F066	A0A1L8F3F3	WH1 domain-containing protein.	WH1 domain-containing protein.	0.912
A0A1L8F066	Vasp.L	A0A1L8F066	A0A1L8F854	WH1 domain-containing protein.	WH1 domain-containing protein.	0.912
A0A1L8F3F3	A0A1L8F066	A0A1L8F3F3	A0A1L8F066	WH1 domain-containing protein.	WH1 domain-containing protein.	0.912
A0A1L8F3F3	Cfl1.L	A0A1L8F3F3	A0A1L8GJZ1	WH1 domain-containing protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.501
A0A1L8F3F3	evl	A0A1L8F3F3	A0A1L8F9X3	WH1 domain-containing protein.	WH1 domain-containing protein.	0.912
A0A1L8FET5	A0A1L8FJQ6	A0A1L8FET5	A0A1L8FJQ6	Phosphoinositide phospholipase C.	Uncharacterized protein.	0.900
A0A1L8FJQ6	A0A1L8FET5	A0A1L8FJQ6	A0A1L8FET5	Uncharacterized protein.	Phosphoinositide phospholipase C.	0.900
Cfl1.L	A0A1L8F3F3	A0A1L8GJZ1	A0A1L8F3F3	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	WH1 domain-containing protein.	0.501
Cfl1.L	Epha2.L	A0A1L8GJZ1	A0A1L8FPA0	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.400
Cfl1.L	Vasp.L	A0A1L8GJZ1	A0A1L8F854	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	WH1 domain-containing protein.	0.577
Dpp4.L	A0A1L8EW16	A0A1L8EW34	A0A1L8EW16	Uncharacterized protein; Belongs to the peptidase S9B family.	Uncharacterized protein.	0.676
Dpp4.L	Fap.L	A0A1L8EW34	A0A1L8EW08	Uncharacterized protein; Belongs to the peptidase S9B family.	DPPIV_N domain-containing protein.	0.687
Dpp4.L	Gcg.L	A0A1L8EW34	A0A1L8EW01	Uncharacterized protein; Belongs to the peptidase S9B family.	Uncharacterized protein.	0.676
Dpp4.L	Gcg2	A0A1L8EW34	A0A1L8EP35	Uncharacterized protein; Belongs to the peptidase S9B family.	Uncharacterized protein.	0.676
Epha2.L	Cfl1.L	A0A1L8FPA0	A0A1L8GJZ1	Uncharacterized protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.400
Fap.L	A0A1L8EW78	A0A1L8EW08	A0A1L8EW78	DPPIV_N domain-containing protein.	Peptidase_S9 domain-containing protein.	0.491
Fap.L	Dpp4.L	A0A1L8EW08	A0A1L8EW34	DPPIV_N domain-containing protein.	Uncharacterized protein; Belongs to the peptidase S9B family.	0.687