(11 nodes) Frizzled/Smoothened, transmembrane domain network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fzd6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
	A0A1L8EPZ4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
	A0A1L8ES96	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (554 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	A0A1L8EX74	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	fz3	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	fzd10a	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
	fzd9-2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
	fzd9	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
	fzd3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EPZ4	fzd6	A0A1L8EPZ4	A0A1L8FZR1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.402
A0A1L8ES96	fzd6	A0A1L8ES96	A0A1L8FZR1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.412
A0A1L8EX74	fzd6	A0A1L8EX74	A0A1L8FZR1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.406
fz3	fzd10a	B7ZQS8	B7ZQP6	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family.	0.438
fz3	fzd6	B7ZQS8	A0A1L8FZR1	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.581
fzd10a	fz3	B7ZQP6	B7ZQS8	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family.	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.438
fzd10a	fzd3	B7ZQP6	A0A1L8G5I1	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.434
fzd10a	fzd6	B7ZQP6	A0A1L8FZR1	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.473
fzd10a	xfz8	B7ZQP6	B7ZQV9	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.473
fzd3	fzd10a	A0A1L8G5I1	B7ZQP6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family.	0.434
fzd3	fzd6	A0A1L8G5I1	A0A1L8FZR1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.581
fzd3	fzd9	A0A1L8G5I1	A0A1L8H5V1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.407
fzd3	fzd9-2	A0A1L8G5I1	A0A1L8HDG3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.407
fzd3	xfz8	A0A1L8G5I1	B7ZQV9	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.401
fzd6	A0A1L8EPZ4	A0A1L8FZR1	A0A1L8EPZ4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.402
fzd6	A0A1L8ES96	A0A1L8FZR1	A0A1L8ES96	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.412
fzd6	A0A1L8EX74	A0A1L8FZR1	A0A1L8EX74	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.406
fzd6	fz3	A0A1L8FZR1	B7ZQS8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.581
fzd6	fzd10a	A0A1L8FZR1	B7ZQP6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family.	0.473
fzd6	fzd3	A0A1L8FZR1	A0A1L8G5I1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.581