(18 nodes) Cystine knot, C-terminal network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8FU26	Uncharacterized protein. (358 aa)
	sostdc1-2	Wise-A. (213 aa)
	Nov.L	Uncharacterized protein. (343 aa)
	ccn2	Ctgf protein. (343 aa)
	grem1	Gremlin. (182 aa)
	ccn1l	LOC100137691 protein. (385 aa)
	A0A1L8HF49	CTCK domain-containing protein. (132 aa)
	ndp	CTCK domain-containing protein. (132 aa)
	dand5	CTCK domain-containing protein. (219 aa)
	vwf	Uncharacterized protein. (2841 aa)
	A0A1L8GLM2	Uncharacterized protein. (375 aa)
	gpha2	CTCK domain-containing protein. (125 aa)
	A0A1L8GCX0	Uncharacterized protein. (374 aa)
	sostdc1	CTCK domain-containing protein. (213 aa)
	ccn3	Uncharacterized protein. (345 aa)
	nbl1	CTCK domain-containing protein. (171 aa)
	A0A1L8F8K5	CTCK domain-containing protein. (271 aa)
	A0A1L8ELA8	Uncharacterized protein. (312 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GLM2	ccn2	A0A1L8GLM2	Q505L5	Uncharacterized protein.	Ctgf protein.	0.672
ccn1l	ccn2	A9UMN6	Q505L5	LOC100137691 protein.	Ctgf protein.	0.572
ccn2	A0A1L8GLM2	Q505L5	A0A1L8GLM2	Ctgf protein.	Uncharacterized protein.	0.672
ccn2	ccn1l	Q505L5	A9UMN6	Ctgf protein.	LOC100137691 protein.	0.572
ccn2	vwf	Q505L5	A0A1L8GWR2	Ctgf protein.	Uncharacterized protein.	0.584
grem1	sostdc1	B7ZQZ5	A0A1L8FVV7	Gremlin.	CTCK domain-containing protein.	0.426
grem1	sostdc1-2	B7ZQZ5	Q6VYA2	Gremlin.	Wise-A.	0.426
sostdc1	grem1	A0A1L8FVV7	B7ZQZ5	CTCK domain-containing protein.	Gremlin.	0.426
sostdc1-2	grem1	Q6VYA2	B7ZQZ5	Wise-A.	Gremlin.	0.426
vwf	ccn2	A0A1L8GWR2	Q505L5	Uncharacterized protein.	Ctgf protein.	0.584