21 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sel1l	Fibronectin type-II domain-containing protein. (824 aa)
	mmp9	Gelatinase B. (671 aa)
	ror2-2	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (607 aa)
	kremen1	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
	prss12	Uncharacterized protein; Belongs to the peptidase S1 family. (851 aa)
	hgfac	Uncharacterized protein. (595 aa)
	ror2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	plat	Plasminogen activator; Belongs to the peptidase S1 family. (566 aa)
	hgf-2	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	mst1	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (718 aa)
	A0A1L8GM33	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (944 aa)
	Mst1.S	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (716 aa)
	A0A1L8GFH0	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (946 aa)
	A0A1L8FK09	Uncharacterized protein; Belongs to the peptidase S1 family. (829 aa)
	Habp2.L	Uncharacterized protein. (529 aa)
	kremen2	Uncharacterized protein. (420 aa)
	A0A1L8EWN9	Uncharacterized protein. (2484 aa)
	A0A1L8EVZ0	Uncharacterized protein. (1719 aa)
	A0A1L8EMB1	Uncharacterized protein. (683 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EMB1	plat	A0A1L8EMB1	A0A1L8H251	Uncharacterized protein.	Plasminogen activator; Belongs to the peptidase S1 family.	0.437
A0A1L8GFH0	ror2	A0A1L8GFH0	A0A1L8HPI6	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.566
A0A1L8GFH0	ror2-2	A0A1L8GFH0	Q8AV69	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.567
A0A1L8GM33	ror2	A0A1L8GM33	A0A1L8HPI6	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.567
A0A1L8GM33	ror2-2	A0A1L8GM33	Q8AV69	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.566
Habp2.L	f2	A0A1L8FI40	Q6DFJ5	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.436
Habp2.L	hgfac	A0A1L8FI40	A0A1L8HT91	Uncharacterized protein.	Uncharacterized protein.	0.524
Habp2.L	plat	A0A1L8FI40	A0A1L8H251	Uncharacterized protein.	Plasminogen activator; Belongs to the peptidase S1 family.	0.401
Mst1.S	hgfac	A0A1L8GHB0	A0A1L8HT91	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily.	Uncharacterized protein.	0.545
f2	Habp2.L	Q6DFJ5	A0A1L8FI40	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.436
f2	hgfac	Q6DFJ5	A0A1L8HT91	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.500
f2	plat	Q6DFJ5	A0A1L8H251	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Plasminogen activator; Belongs to the peptidase S1 family.	0.437
hgf	hgf-2	A0A1L8GTY1	A0A1L8GZD1	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.404
hgf	hgfac	A0A1L8GTY1	A0A1L8HT91	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Uncharacterized protein.	0.689
hgf	mmp9	A0A1L8GTY1	Q9W7L6	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Gelatinase B.	0.450
hgf-2	hgf	A0A1L8GZD1	A0A1L8GTY1	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.404
hgf-2	hgfac	A0A1L8GZD1	A0A1L8HT91	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Uncharacterized protein.	0.689
hgf-2	mmp9	A0A1L8GZD1	Q9W7L6	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Gelatinase B.	0.450
hgfac	Habp2.L	A0A1L8HT91	A0A1L8FI40	Uncharacterized protein.	Uncharacterized protein.	0.524
hgfac	Mst1.S	A0A1L8HT91	A0A1L8GHB0	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.545