(53 nodes) Periplasmic binding protein-like I network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8GHK7	G_PROTEIN_RECEP_F3_4 domain-containing protein. (909 aa)
	gucy2c	Guanylate cyclase. (1065 aa)
	grin2b	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable); Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B sub [...] (1448 aa)
	A0A310TNT7	G_PROTEIN_RECEP_F3_4 domain-containing protein. (872 aa)
	A0A310TNR2	G_PROTEIN_RECEP_F3_4 domain-containing protein. (871 aa)
	A0A1L8HWN4	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1005 aa)
	A0A1L8HST2	G_PROTEIN_RECEP_F3_4 domain-containing protein. (879 aa)
	npr3	ANF_receptor domain-containing protein. (507 aa)
	A0A1L8HN96	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (998 aa)
	A0A1L8HJY9	Guanylate cyclase. (1105 aa)
	A0A1L8HCM2	Uncharacterized protein. (923 aa)
	A0A1L8HB42	G_PROTEIN_RECEP_F3_4 domain-containing protein. (1172 aa)
	A0A1L8H716	G_PROTEIN_RECEP_F3_4 domain-containing protein. (912 aa)
	A0A1L8H5K9	G_PROTEIN_RECEP_F3_4 domain-containing protein. (1045 aa)
	A0A1L8H3U5	G_PROTEIN_RECEP_F3_4 domain-containing protein. (785 aa)
	A0A1L8H3L3	G_PROTEIN_RECEP_F3_4 domain-containing protein. (844 aa)
	A0A1L8H3K5	G_PROTEIN_RECEP_F3_4 domain-containing protein. (842 aa)
	A0A1L8H3J2	G_PROTEIN_RECEP_F3_4 domain-containing protein. (877 aa)
	A0A1L8H3I4	G_PROTEIN_RECEP_F3_4 domain-containing protein. (828 aa)
	A0A1L8H3H7	G_PROTEIN_RECEP_F3_4 domain-containing protein. (850 aa)
	gucy2d	Guanylate cyclase. (1078 aa)
	grm3-2	G_PROTEIN_RECEP_F3_4 domain-containing protein. (878 aa)
	Gria1.L	Uncharacterized protein. (902 aa)
	grm3	G_PROTEIN_RECEP_F3_4 domain-containing protein. (878 aa)
	A0A1L8GR36	Uncharacterized protein. (902 aa)
	A0A1L8GPM9	G_PROTEIN_RECEP_F3_4 domain-containing protein. (909 aa)
	Grm2.L	G_PROTEIN_RECEP_F3_4 domain-containing protein. (888 aa)
	Grin2b.L	Uncharacterized protein. (1449 aa)
	A0A1L8GGS3	Guanylate cyclase. (1065 aa)
	A0A1L8G904	G_PROTEIN_RECEP_F3_4 domain-containing protein. (904 aa)
	Grik2.L	Uncharacterized protein. (913 aa)
	gprc6a	G_PROTEIN_RECEP_F3_4 domain-containing protein. (906 aa)
	A0A1L8G8T6	G_PROTEIN_RECEP_F3_4 domain-containing protein. (884 aa)
	A0A1L8G8N4	G_PROTEIN_RECEP_F3_4 domain-containing protein. (924 aa)
	A0A1L8G221	G_PROTEIN_RECEP_F3_4 domain-containing protein. (1170 aa)
	A0A1L8FNL7	Uncharacterized protein. (1364 aa)
	grik5-2	Uncharacterized protein. (995 aa)
	A0A1L8FMU1	G_PROTEIN_RECEP_F3_4 domain-containing protein. (773 aa)
	A0A1L8FMT1	G_PROTEIN_RECEP_F3_4 domain-containing protein. (771 aa)
	Grik4.L	Uncharacterized protein. (993 aa)
	A0A1L8FI39	Guanylate cyclase. (1122 aa)
	grik5	Uncharacterized protein. (995 aa)
	A0A1L8FFY4	Uncharacterized protein. (958 aa)
	A0A1L8FBM2	G_PROTEIN_RECEP_F3_4 domain-containing protein. (862 aa)
	A0A1L8FBJ7	G_PROTEIN_RECEP_F3_4 domain-containing protein. (781 aa)
	gabbr1	Uncharacterized protein. (980 aa)
	gria3	Uncharacterized protein. (887 aa)
	grin1	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (Ref.11,. Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable). (903 aa)
	A0A1L8F440	G_PROTEIN_RECEP_F3_4 domain-containing protein. (884 aa)
	Gabbr1.S	Uncharacterized protein. (987 aa)
	gucy2f	Guanylate cyclase. (1112 aa)
	Grin1.S	Uncharacterized protein. (883 aa)
	A0A1L8EMV1	Uncharacterized protein. (1189 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EMV1	A0A1L8HN96	A0A1L8EMV1	A0A1L8HN96	Uncharacterized protein.	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.611
A0A1L8EMV1	A0A1L8HWN4	A0A1L8EMV1	A0A1L8HWN4	Uncharacterized protein.	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.611
A0A1L8EMV1	Grin1.S	A0A1L8EMV1	A0A1L8F0T7	Uncharacterized protein.	Uncharacterized protein.	0.835
A0A1L8EMV1	Grin2b.L	A0A1L8EMV1	A0A1L8GND5	Uncharacterized protein.	Uncharacterized protein.	0.733
A0A1L8EMV1	grin1	A0A1L8EMV1	A0A1L8F5J9	Uncharacterized protein.	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (Ref.11,. Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable).	0.889
A0A1L8EMV1	grin2b	A0A1L8EMV1	A7XY94	Uncharacterized protein.	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable); Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B sub [...]	0.733
A0A1L8F440	Gabbr1.S	A0A1L8F440	A0A1L8F3J3	G_PROTEIN_RECEP_F3_4 domain-containing protein.	Uncharacterized protein.	0.437
A0A1L8F440	Grm2.L	A0A1L8F440	A0A1L8GPG5	G_PROTEIN_RECEP_F3_4 domain-containing protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.576
A0A1L8F440	gabbr1	A0A1L8F440	A0A1L8F895	G_PROTEIN_RECEP_F3_4 domain-containing protein.	Uncharacterized protein.	0.437
A0A1L8F440	grm3	A0A1L8F440	A0A1L8GTT9	G_PROTEIN_RECEP_F3_4 domain-containing protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.469
A0A1L8F440	grm3-2	A0A1L8F440	A0A1L8GZI3	G_PROTEIN_RECEP_F3_4 domain-containing protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.469
A0A1L8FFY4	A0A1L8HCM2	A0A1L8FFY4	A0A1L8HCM2	Uncharacterized protein.	Uncharacterized protein.	0.601
A0A1L8FFY4	Grik2.L	A0A1L8FFY4	A0A1L8G8Y6	Uncharacterized protein.	Uncharacterized protein.	0.599
A0A1L8FNL7	A0A1L8HN96	A0A1L8FNL7	A0A1L8HN96	Uncharacterized protein.	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.580
A0A1L8FNL7	A0A1L8HWN4	A0A1L8FNL7	A0A1L8HWN4	Uncharacterized protein.	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.580
A0A1L8FNL7	Grin1.S	A0A1L8FNL7	A0A1L8F0T7	Uncharacterized protein.	Uncharacterized protein.	0.835
A0A1L8FNL7	Grin2b.L	A0A1L8FNL7	A0A1L8GND5	Uncharacterized protein.	Uncharacterized protein.	0.600
A0A1L8FNL7	grin1	A0A1L8FNL7	A0A1L8F5J9	Uncharacterized protein.	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (Ref.11,. Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable).	0.835
A0A1L8FNL7	grin2b	A0A1L8FNL7	A7XY94	Uncharacterized protein.	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable); Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B sub [...]	0.600
A0A1L8G221	A0A1L8HB42	A0A1L8G221	A0A1L8HB42	G_PROTEIN_RECEP_F3_4 domain-containing protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.901