24 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mst1	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (718 aa)
	A0A1L8GM33	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (944 aa)
	F2.L	Uncharacterized protein; Belongs to the peptidase S1 family. (564 aa)
	Mst1.S	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (716 aa)
	A0A1L8GFH0	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (946 aa)
	A0A1L8G2F6	Uncharacterized protein. (566 aa)
	A0A1L8FK09	Uncharacterized protein; Belongs to the peptidase S1 family. (829 aa)
	Habp2.L	Uncharacterized protein. (529 aa)
	kremen2	Uncharacterized protein. (420 aa)
	Kremen2.S	Uncharacterized protein. (421 aa)
	hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	f12	Uncharacterized protein. (544 aa)
	hgf-2	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	plat	Plasminogen activator; Belongs to the peptidase S1 family. (566 aa)
	A0A1L8HKX6	Uncharacterized protein; Belongs to the peptidase S1 family. (556 aa)
	Musk.S	Uncharacterized protein. (942 aa)
	ror2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	Kremen1.S	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (452 aa)
	hgfac	Uncharacterized protein. (595 aa)
	prss12	Uncharacterized protein; Belongs to the peptidase S1 family. (851 aa)
	A0A1L8HXQ0	Uncharacterized protein. (903 aa)
	kremen1	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (607 aa)
	ror2-2	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FK09	Musk.S	A0A1L8FK09	A0A1L8HNT6	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.673
A0A1L8G2F6	A0A1L8HKX6	A0A1L8G2F6	A0A1L8HKX6	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.403
A0A1L8G2F6	F2.L	A0A1L8G2F6	A0A1L8GIR4	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.778
A0A1L8G2F6	Habp2.L	A0A1L8G2F6	A0A1L8FI40	Uncharacterized protein.	Uncharacterized protein.	0.527
A0A1L8G2F6	f12	A0A1L8G2F6	A0A1L8GXU3	Uncharacterized protein.	Uncharacterized protein.	0.403
A0A1L8G2F6	f2	A0A1L8G2F6	Q6DFJ5	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.823
A0A1L8G2F6	hgfac	A0A1L8G2F6	A0A1L8HT91	Uncharacterized protein.	Uncharacterized protein.	0.542
A0A1L8G2F6	plat	A0A1L8G2F6	A0A1L8H251	Uncharacterized protein.	Plasminogen activator; Belongs to the peptidase S1 family.	0.922
A0A1L8GFH0	ror2	A0A1L8GFH0	A0A1L8HPI6	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.566
A0A1L8GFH0	ror2-2	A0A1L8GFH0	Q8AV69	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.567
A0A1L8GM33	ror2	A0A1L8GM33	A0A1L8HPI6	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.567
A0A1L8GM33	ror2-2	A0A1L8GM33	Q8AV69	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.566
A0A1L8HKX6	A0A1L8G2F6	A0A1L8HKX6	A0A1L8G2F6	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.403
A0A1L8HKX6	F2.L	A0A1L8HKX6	A0A1L8GIR4	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.444
A0A1L8HKX6	Habp2.L	A0A1L8HKX6	A0A1L8FI40	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.442
A0A1L8HKX6	Mst1.S	A0A1L8HKX6	A0A1L8GHB0	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.545
A0A1L8HKX6	f2	A0A1L8HKX6	Q6DFJ5	Uncharacterized protein; Belongs to the peptidase S1 family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.444
A0A1L8HKX6	hgf	A0A1L8HKX6	A0A1L8GTY1	Uncharacterized protein; Belongs to the peptidase S1 family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.626
A0A1L8HKX6	hgf-2	A0A1L8HKX6	A0A1L8GZD1	Uncharacterized protein; Belongs to the peptidase S1 family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.626
A0A1L8HKX6	mst1	A0A1L8HKX6	A0A1L8GP52	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.545