82 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fndc3a-2	Uncharacterized protein. (1200 aa)
	mmp9	Gelatinase B. (671 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	kras-3	LOC397771 protein. (186 aa)
	hras	Small G-protein H-Ras. (189 aa)
	kitlg	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (270 aa)
	yes1	Tyrosine-protein kinase. (537 aa)
	pik3r1	MGC80357 protein. (722 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	pik3r2	Pik3r2-prov protein. (457 aa)
	kras-2	Uncharacterized protein. (187 aa)
	pik3r3	MGC84470 protein. (461 aa)
	krasl	Uncharacterized protein. (187 aa)
	ptpn6-2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (587 aa)
	src	Tyrosine-protein kinase. (532 aa)
	PIK3R1	Phosphoinositide-3-kinase. (722 aa)
	G67.L	Uncharacterized protein. (718 aa)
	Fer.L	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (774 aa)
	A0A1L8I158	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
	sh2b3	Uncharacterized protein. (618 aa)
	A0A1L8HWT4	Uncharacterized protein. (717 aa)
	Kit.L	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
	fer	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	Sh2b3.S	SH2 domain-containing protein. (617 aa)
	A0A1L8HNI8	Uncharacterized protein. (721 aa)
	Kit.S	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
	gab2-2	PH domain-containing protein. (677 aa)
	A0A1L8HIC2	Uncharacterized protein. (349 aa)
	A0A1L8HI67	Uncharacterized protein. (349 aa)
	LOC100496837.L	Uncharacterized protein. (360 aa)
	A0A1L8HI45	Uncharacterized protein. (363 aa)
	A0A1L8HI41	Uncharacterized protein. (330 aa)
	A0A1L8HFH3	Uncharacterized protein. (1374 aa)
	Csde1.L	Uncharacterized protein. (780 aa)
	A0A1L8HE12	Uncharacterized protein. (122 aa)
	nras	Uncharacterized protein. (189 aa)
	A0A1L8HCC4	Uncharacterized protein. (141 aa)
	gab2	PH domain-containing protein. (673 aa)
	fndc3a	Uncharacterized protein. (1202 aa)
	A0A1L8HA21	Uncharacterized protein. (331 aa)
	A0A1L8H9Z4	Uncharacterized protein. (263 aa)
	A0A1L8H9W0	Uncharacterized protein. (359 aa)
	A0A1L8H940	Uncharacterized protein. (137 aa)
	A0A1L8H7X8	Uncharacterized protein. (1433 aa)
	csde1	Uncharacterized protein. (833 aa)
	fes	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	Kitlg.S	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (270 aa)
	Fes.S	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (849 aa)
	grap2-2	Uncharacterized protein. (301 aa)
	grap2	Uncharacterized protein. (303 aa)
	fndc3b-2	Uncharacterized protein. (1204 aa)
	A0A1L8GA65	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1009 aa)
	sos1-2	Uncharacterized protein. (1325 aa)
	fndc3b	Uncharacterized protein. (1205 aa)
	A0A1L8G3Z7	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	sos1	Uncharacterized protein. (1325 aa)
	lyn-2	Tyrosine-protein kinase. (508 aa)
	grb10-2	Uncharacterized protein. (591 aa)
	lyn	Tyrosine-protein kinase. (508 aa)
	A0A1L8FSV1	Tyrosine-protein kinase. (400 aa)
	grb10	Uncharacterized protein. (535 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	kras	Uncharacterized protein. (186 aa)
	A0A1L8FG16	Uncharacterized protein. (559 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	ptpn6	Uncharacterized protein. (687 aa)
	fndc3c	Uncharacterized protein. (1205 aa)
	A0A1L8F3B0	Uncharacterized protein. (1205 aa)
	grap-2	Uncharacterized protein. (219 aa)
	grb14	Uncharacterized protein. (451 aa)
	grb2-2	Uncharacterized protein. (229 aa)
	A0A1L8EU06	Uncharacterized protein. (574 aa)
	Mmp9.L	Uncharacterized protein. (674 aa)
	grb7-2	Uncharacterized protein. (532 aa)
	stat3.1	Signal transducer and activator of transcription. (769 aa)
	Stat3.2.L	Signal transducer and activator of transcription. (760 aa)
	grap	Uncharacterized protein. (219 aa)
	A0A1L8EP71	Uncharacterized protein. (430 aa)
	grb2	Uncharacterized protein. (229 aa)
	A0A1L8EMB1	Uncharacterized protein. (683 aa)
	grb7	Uncharacterized protein. (532 aa)
	A0A1L8EKH9	STAT_int domain-containing protein. (635 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKH9	A0A1L8FG16	A0A1L8EKH9	A0A1L8FG16	STAT_int domain-containing protein.	Uncharacterized protein.	0.567
A0A1L8EKH9	A0A1L8FSV1	A0A1L8EKH9	A0A1L8FSV1	STAT_int domain-containing protein.	Tyrosine-protein kinase.	0.657
A0A1L8EKH9	A0A1L8I158	A0A1L8EKH9	A0A1L8I158	STAT_int domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.567
A0A1L8EKH9	G67.L	A0A1L8EKH9	A0A310TNC8	STAT_int domain-containing protein.	Uncharacterized protein.	0.473
A0A1L8EKH9	Kit.L	A0A1L8EKH9	A0A1L8HTR4	STAT_int domain-containing protein.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.473
A0A1L8EKH9	Kit.S	A0A1L8EKH9	A0A1L8HL85	STAT_int domain-containing protein.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.473
A0A1L8EKH9	Kitlg.S	A0A1L8EKH9	A0A1L8GUP3	STAT_int domain-containing protein.	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.	0.492
A0A1L8EKH9	Ptpn11.S	A0A1L8EKH9	Q92124	STAT_int domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.610
A0A1L8EKH9	grb2	A0A1L8EKH9	A0A1L8EMZ6	STAT_int domain-containing protein.	Uncharacterized protein.	0.457
A0A1L8EKH9	grb2-2	A0A1L8EKH9	A0A1L8EUF2	STAT_int domain-containing protein.	Uncharacterized protein.	0.457
A0A1L8EKH9	kitlg	A0A1L8EKH9	Q7ZXV0	STAT_int domain-containing protein.	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.	0.492
A0A1L8EKH9	lyn	A0A1L8EKH9	A0A1L8FT48	STAT_int domain-containing protein.	Tyrosine-protein kinase.	0.678
A0A1L8EKH9	lyn-2	A0A1L8EKH9	A0A1L8FZ11	STAT_int domain-containing protein.	Tyrosine-protein kinase.	0.678
A0A1L8EKH9	ptpn11b	A0A1L8EKH9	Q6GP31	STAT_int domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.610
A0A1L8EKH9	ptpn6	A0A1L8EKH9	A0A1L8FDW3	STAT_int domain-containing protein.	Uncharacterized protein.	0.423
A0A1L8EKH9	ptpn6-2	A0A1L8EKH9	Q4V854	STAT_int domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.423
A0A1L8EKH9	src	A0A1L8EKH9	Q2TAR1	STAT_int domain-containing protein.	Tyrosine-protein kinase.	0.746
A0A1L8EKH9	yes1	A0A1L8EKH9	Q6PF70	STAT_int domain-containing protein.	Tyrosine-protein kinase.	0.657
A0A1L8EMB1	Kitlg.S	A0A1L8EMB1	A0A1L8GUP3	Uncharacterized protein.	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.	0.625
A0A1L8EMB1	kitlg	A0A1L8EMB1	Q7ZXV0	Uncharacterized protein.	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.	0.625