(17 nodes) PKA activation in glucagon signalling network (Xenopus laevis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	prkar1b	Uncharacterized protein. (380 aa)
	prkar1b-2	Uncharacterized protein. (380 aa)
	thap7	Uncharacterized protein. (440 aa)
	A0A1L8FMR5	Uncharacterized protein. (440 aa)
	A0A1L8FUU7	Cyclic nucleotide-binding domain-containing protein. (594 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
	A0A1L8GHR4	Uncharacterized protein. (405 aa)
	Prkacb.S	Uncharacterized protein; Belongs to the protein kinase superfamily. (338 aa)
	A0A1L8GPR3	Uncharacterized protein. (404 aa)
	Prkar2b.S	Uncharacterized protein. (402 aa)
	A0A1L8GZ80	Uncharacterized protein. (406 aa)
	A0A1L8H2K5	Uncharacterized protein; Belongs to the protein kinase superfamily. (383 aa)
	A0A1L8HTS5	Cyclic nucleotide-binding domain-containing protein. (329 aa)
	thap1	THAP-type domain-containing protein. (225 aa)
	prkar1a	MGC82149 protein. (381 aa)
	prkar1a-2	Prkar1a protein. (381 aa)
	prkaca	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FMR5	A0A1L8FUU7	A0A1L8FMR5	A0A1L8FUU7	Uncharacterized protein.	Cyclic nucleotide-binding domain-containing protein.	0.682
A0A1L8FMR5	A0A1L8GHR4	A0A1L8FMR5	A0A1L8GHR4	Uncharacterized protein.	Uncharacterized protein.	0.682
A0A1L8FMR5	A0A1L8GPR3	A0A1L8FMR5	A0A1L8GPR3	Uncharacterized protein.	Uncharacterized protein.	0.682
A0A1L8FMR5	A0A1L8GZ80	A0A1L8FMR5	A0A1L8GZ80	Uncharacterized protein.	Uncharacterized protein.	0.682
A0A1L8FMR5	A0A1L8HTS5	A0A1L8FMR5	A0A1L8HTS5	Uncharacterized protein.	Cyclic nucleotide-binding domain-containing protein.	0.682
A0A1L8FMR5	Prkar2b.S	A0A1L8FMR5	A0A1L8GTZ4	Uncharacterized protein.	Uncharacterized protein.	0.682
A0A1L8FMR5	prkar1a	A0A1L8FMR5	Q6DJJ2	Uncharacterized protein.	MGC82149 protein.	0.682
A0A1L8FMR5	prkar1a-2	A0A1L8FMR5	Q6INK7	Uncharacterized protein.	Prkar1a protein.	0.682
A0A1L8FMR5	prkar1b	A0A1L8FMR5	A0A1L8EQL8	Uncharacterized protein.	Uncharacterized protein.	0.682
A0A1L8FMR5	prkar1b-2	A0A1L8FMR5	A0A1L8EXW8	Uncharacterized protein.	Uncharacterized protein.	0.682
A0A1L8FUU7	A0A1L8FMR5	A0A1L8FUU7	A0A1L8FMR5	Cyclic nucleotide-binding domain-containing protein.	Uncharacterized protein.	0.682
A0A1L8FUU7	A0A1L8H2K5	A0A1L8FUU7	A0A1L8H2K5	Cyclic nucleotide-binding domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.682
A0A1L8FUU7	Prkacb.S	A0A1L8FUU7	A0A1L8GLU4	Cyclic nucleotide-binding domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.682
A0A1L8FUU7	prkaca	A0A1L8FUU7	Q90WN3	Cyclic nucleotide-binding domain-containing protein.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.682
A0A1L8FUU7	prkacb	A0A1L8FUU7	A0A1L8GFG6	Cyclic nucleotide-binding domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.682
A0A1L8FUU7	thap1	A0A1L8FUU7	A0A1L8HXK5	Cyclic nucleotide-binding domain-containing protein.	THAP-type domain-containing protein.	0.682
A0A1L8FUU7	thap7	A0A1L8FUU7	A0A1L8FGL1	Cyclic nucleotide-binding domain-containing protein.	Uncharacterized protein.	0.682
A0A1L8GHR4	A0A1L8FMR5	A0A1L8GHR4	A0A1L8FMR5	Uncharacterized protein.	Uncharacterized protein.	0.682
A0A1L8GHR4	A0A1L8H2K5	A0A1L8GHR4	A0A1L8H2K5	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.771
A0A1L8GHR4	Prkacb.S	A0A1L8GHR4	A0A1L8GLU4	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.771