(89 nodes) Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8HY24	Thioredoxin domain-containing protein. (108 aa)
	A0A1L8ELD5	TMEM189_B_dmain domain-containing protein. (249 aa)
	A0A1L8ELD8	UBIQUITIN_CONJUGAT_2 domain-containing protein. (186 aa)
	Birc7.L	RING-type domain-containing protein. (401 aa)
	A0A1L8ELY1	BH4_2 domain-containing protein. (219 aa)
	A0A1L8EP79	Uncharacterized protein. (788 aa)
	Ube2v1.L	UBIQUITIN_CONJUGAT_2 domain-containing protein. (201 aa)
	A0A1L8ET49	RING-type domain-containing protein. (407 aa)
	A0A1L8ETC2	BH4_2 domain-containing protein. (212 aa)
	A0A1L8EW93	Uncharacterized protein. (793 aa)
	Nme9.L	Uncharacterized protein; Belongs to the NDK family. (625 aa)
	txnip	Arrestin_C domain-containing protein. (388 aa)
	arrdc1	Arrestin_C domain-containing protein. (425 aa)
	Txnip.L	Arrestin_C domain-containing protein. (388 aa)
	A0A1L8FCP4	NACHT domain-containing protein. (882 aa)
	A0A1L8FCP9	NACHT domain-containing protein. (896 aa)
	nlrp3	NACHT domain-containing protein. (882 aa)
	A0A1L8FCQ3	NACHT domain-containing protein. (883 aa)
	A0A1L8FCS0	NACHT domain-containing protein. (883 aa)
	A0A1L8FDU4	Uncharacterized protein; Belongs to the peptidase C14A family. (423 aa)
	Casp2.L	Uncharacterized protein; Belongs to the peptidase C14A family. (423 aa)
	nod1	Uncharacterized protein. (946 aa)
	Bcl2.S	BH4_2 domain-containing protein. (253 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	ripk2	Uncharacterized protein. (550 aa)
	A0A1L8FXP7	BH4_2 domain-containing protein. (300 aa)
	ripk2-2	Uncharacterized protein. (545 aa)
	tab2	Uncharacterized protein. (690 aa)
	A0A1L8G366	Protein kinase domain-containing protein. (588 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	nlrc4	Uncharacterized protein. (1015 aa)
	A0A1L8G8E8	Uncharacterized protein. (690 aa)
	tab1	PPM-type phosphatase domain-containing protein. (500 aa)
	A0A1L8GHX3	Mitogen-activated protein kinase. (359 aa)
	A0A1L8GKF8	Uncharacterized protein. (1010 aa)
	A0A1L8GKL1	Uncharacterized protein. (495 aa)
	arrdc4	Arrestin_C domain-containing protein. (399 aa)
	pstpip1	Uncharacterized protein. (424 aa)
	Mapk11.S	Mitogen-activated protein kinase. (361 aa)
	A0A1L8GYZ5	Mitogen-activated protein kinase. (363 aa)
	P38-beta	Mitogen-activated protein kinase. (401 aa)
	Pstpip1.L	Uncharacterized protein. (372 aa)
	arrdc4-2	Arrestin_C domain-containing protein. (396 aa)
	A0A1L8H8J1	Uncharacterized protein. (463 aa)
	A0A1L8H8K5	Uncharacterized protein. (84 aa)
	A0A1L8H8N6	RanBP2-type domain-containing protein. (81 aa)
	A0A1L8H9B9	Uncharacterized protein. (264 aa)
	birc2	Uncharacterized protein. (609 aa)
	A0A1L8HAU6	Uncharacterized protein. (245 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	A0A1L8HEQ1	Uncharacterized protein. (122 aa)
	A0A1L8HER3	Protein kinase domain-containing protein. (107 aa)
	A0A1L8HES6	Uncharacterized protein. (553 aa)
	tab3	Uncharacterized protein. (692 aa)
	sugt1	Uncharacterized protein. (331 aa)
	birc2-2	Uncharacterized protein. (616 aa)
	panx1	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (428 aa)
	Arrdc2.S	Arrestin_C domain-containing protein. (424 aa)
	A0A1L8HNW1	Thioredoxin domain-containing protein. (151 aa)
	Bcl2l2.S	BH4_2 domain-containing protein. (188 aa)
	ubc	Uncharacterized protein. (533 aa)
	arrdc3	Arrestin_C domain-containing protein. (412 aa)
	A0A1L8HS56	F-BAR domain-containing protein. (296 aa)
	arrdc2	Arrestin_C domain-containing protein. (420 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	A0A1L8HXP2	Thioredoxin domain-containing protein. (150 aa)
	A0A1L8I050	Uncharacterized protein; Belongs to the peptidase C19 family. (807 aa)
	P2rx7.L	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (553 aa)
	arrdc3-2	Arrestin_C domain-containing protein. (412 aa)
	A0A1L8I1X3	NACHT domain-containing protein. (1304 aa)
	A0A1L8I1Y7	NACHT domain-containing protein. (1346 aa)
	A0A1L8I210	NACHT domain-containing protein. (1398 aa)
	A0A1L8I2M8	NACHT domain-containing protein. (1294 aa)
	A0A310TN86	Pyrin domain-containing protein. (91 aa)
	tmem189	TMEM189_B_dmain domain-containing protein. (289 aa)
	LOC100037235	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	LOC398025	TAB1. (498 aa)
	mapk14	Mitogen-activated protein kinase. (361 aa)
	map3k7	MAP3K7 protein. (616 aa)
	MGC116516	Mitogen-activated protein kinase. (359 aa)
	txn	LOC495354 protein. (105 aa)
	arrdc1-2	MGC82619 protein. (425 aa)
	rps27a	MGC81889 protein. (156 aa)
	bcl2l2	MGC80617 protein. (188 aa)
	pstpip2	MGC82532 protein. (333 aa)
	MGC80314	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	uba52	MGC80109 protein. (128 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	mapk12	Mitogen-activated protein kinase. (363 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ELD5	A0A1L8FTA7	A0A1L8ELD5	A0A1L8FTA7	TMEM189_B_dmain domain-containing protein.	Ubiquitin-like domain-containing protein.	0.646
A0A1L8ELD5	A0A1L8HX68	A0A1L8ELD5	A0A1L8HX68	TMEM189_B_dmain domain-containing protein.	Ubiquitin-like domain-containing protein.	0.646
A0A1L8ELD5	uba52	A0A1L8ELD5	Q6GQF3	TMEM189_B_dmain domain-containing protein.	MGC80109 protein.	0.646
A0A1L8ELD8	A0A1L8EP79	A0A1L8ELD8	A0A1L8EP79	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.524
A0A1L8ELD8	A0A1L8ET49	A0A1L8ELD8	A0A1L8ET49	UBIQUITIN_CONJUGAT_2 domain-containing protein.	RING-type domain-containing protein.	0.607
A0A1L8ELD8	A0A1L8EW93	A0A1L8ELD8	A0A1L8EW93	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.524
A0A1L8ELD8	A0A1L8FTA7	A0A1L8ELD8	A0A1L8FTA7	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.997
A0A1L8ELD8	A0A1L8G366	A0A1L8ELD8	A0A1L8G366	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Protein kinase domain-containing protein.	0.524
A0A1L8ELD8	A0A1L8G5V1	A0A1L8ELD8	A0A1L8G5V1	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.998
A0A1L8ELD8	A0A1L8G8E8	A0A1L8ELD8	A0A1L8G8E8	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.789
A0A1L8ELD8	A0A1L8GKL1	A0A1L8ELD8	A0A1L8GKL1	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.524
A0A1L8ELD8	A0A1L8H8J1	A0A1L8ELD8	A0A1L8H8J1	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.789
A0A1L8ELD8	A0A1L8H8K5	A0A1L8ELD8	A0A1L8H8K5	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.789
A0A1L8ELD8	A0A1L8H8N6	A0A1L8ELD8	A0A1L8H8N6	UBIQUITIN_CONJUGAT_2 domain-containing protein.	RanBP2-type domain-containing protein.	0.789
A0A1L8ELD8	A0A1L8HCZ9	A0A1L8ELD8	A0A1L8HCZ9	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.985
A0A1L8ELD8	A0A1L8HX68	A0A1L8ELD8	A0A1L8HX68	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.997
A0A1L8ELD8	A0A1L8I1X3	A0A1L8ELD8	A0A1L8I1X3	UBIQUITIN_CONJUGAT_2 domain-containing protein.	NACHT domain-containing protein.	0.607
A0A1L8ELD8	A0A1L8I1Y7	A0A1L8ELD8	A0A1L8I1Y7	UBIQUITIN_CONJUGAT_2 domain-containing protein.	NACHT domain-containing protein.	0.607
A0A1L8ELD8	A0A1L8I210	A0A1L8ELD8	A0A1L8I210	UBIQUITIN_CONJUGAT_2 domain-containing protein.	NACHT domain-containing protein.	0.607
A0A1L8ELD8	A0A1L8I2M8	A0A1L8ELD8	A0A1L8I2M8	UBIQUITIN_CONJUGAT_2 domain-containing protein.	NACHT domain-containing protein.	0.607