127 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ube2c	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
	Psmd3.S	PCI domain-containing protein. (498 aa)
	psmd11	PCI domain-containing protein. (422 aa)
	psmc5	AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
	cdc27	Uncharacterized protein. (833 aa)
	psma7	Proteasome subunit alpha type. (247 aa)
	Psmd12.S	PCI domain-containing protein. (455 aa)
	psmd3	PCI domain-containing protein. (547 aa)
	psmd11-2	PCI domain-containing protein. (422 aa)
	cdc27-2	Uncharacterized protein. (834 aa)
	psma7-2	Proteasome subunit alpha type. (248 aa)
	Anapc11.L	RING-type domain-containing protein. (143 aa)
	Psmd12.L	PCI domain-containing protein. (455 aa)
	A0A1L8EZQ1	Proteasome subunit alpha type. (236 aa)
	A0A1L8EZW5	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (352 aa)
	Psmc6.S	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	psmc1	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	A0A1L8F0S4	Uncharacterized protein. (84 aa)
	Psmd10.S	ANK_REP_REGION domain-containing protein. (270 aa)
	A0A1L8F3K4	Proteasome subunit beta. (279 aa)
	Psmb9.S	Proteasome subunit beta. (215 aa)
	Psmd8.S	PCI domain-containing protein. (271 aa)
	psmb4	Proteasome subunit beta; Belongs to the peptidase T1B family. (249 aa)
	A0A1L8F5A2	VWFA domain-containing protein. (635 aa)
	anapc2	CULLIN_2 domain-containing protein; Belongs to the cullin family. (810 aa)
	cdc26	Uncharacterized protein. (84 aa)
	psmd5	Uncharacterized protein. (505 aa)
	psmb7	Proteasome subunit beta. (277 aa)
	Psmd8.L	PCI domain-containing protein. (271 aa)
	Psmc1.L	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	psmc6	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	Bub1b.L	Uncharacterized protein. (890 aa)
	Psmb4.L	Proteasome subunit beta; Belongs to the peptidase T1B family. (249 aa)
	A0A1L8FDD6	VWFA domain-containing protein. (377 aa)
	cdk1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
	bub3	Uncharacterized protein. (330 aa)
	anapc16	Uncharacterized protein. (144 aa)
	ube2s	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (211 aa)
	A0A1L8FHS4	Prot_ATP_ID_OB domain-containing protein. (59 aa)
	A0A1L8FHT5	AAA domain-containing protein. (240 aa)
	A0A1L8FHT9	Uncharacterized protein. (94 aa)
	Cdk1.L	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
	bub3-2	Uncharacterized protein. (330 aa)
	anapc16-2	Uncharacterized protein. (144 aa)
	ube2s-2	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (211 aa)
	Anapc15-a	Uncharacterized protein. (120 aa)
	psma2	Proteasome subunit alpha type. (234 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	anapc15	Uncharacterized protein. (120 aa)
	anapc1	APC1_C domain-containing protein. (1948 aa)
	fam89a	Uncharacterized protein. (166 aa)
	A0A1L8G3T0	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (922 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	psme4	Uncharacterized protein. (1828 aa)
	fam89a-2	Uncharacterized protein. (166 aa)
	Psmd13.S	PCI domain-containing protein. (364 aa)
	Psma1.S	Proteasome subunit alpha type. (295 aa)
	psmd7	MPN domain-containing protein. (320 aa)
	A0A1L8GI18	Uncharacterized protein. (364 aa)
	A0A1L8GLZ6	Proteasome subunit alpha type. (261 aa)
	cdc20	WD_REPEATS_REGION domain-containing protein. (512 aa)
	A0A1L8GN61	Uncharacterized protein. (244 aa)
	A0A1L8GQD1	DUF4203 domain-containing protein. (566 aa)
	psmc2	AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
	cdc23	TPR_REGION domain-containing protein. (581 aa)
	Cdc23.L	TPR_REGION domain-containing protein. (580 aa)
	Psmb2.S	Proteasome subunit beta. (199 aa)
	Ccna1.S	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (418 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	Ccna1.L	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (421 aa)
	Ccna2.S	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (415 aa)
	kxd1	KxDL domain-containing protein. (195 aa)
	Psme1.S	Uncharacterized protein. (244 aa)
	A0A1L8HPK4	Uncharacterized protein. (256 aa)
	psmb5	Proteasome subunit beta. (257 aa)
	ubc	Uncharacterized protein. (533 aa)
	anapc4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (789 aa)
	Mad2l1.L	HORMA domain-containing protein. (203 aa)
	Kxd1.L	KxDL domain-containing protein. (195 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	psmb11	Proteasome subunit beta. (276 aa)
	psmb5-2	Proteasome subunit beta. (257 aa)
	Anapc5.L	Uncharacterized protein. (759 aa)
	cdc20b	WD_REPEATS_REGION domain-containing protein. (517 aa)
	A0A310TMH3	DUF4203 domain-containing protein. (227 aa)
	A0A310TNW1	Prot_ATP_ID_OB domain-containing protein. (153 aa)
	psmc2-2	XMSS1 protein; Belongs to the AAA ATPase family. (433 aa)
	psmc3-a	26S proteasome regulatory subunit 6A-A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). (423 aa)
	mad2l1	Mad2l1 protein. (203 aa)
	psmb6	Proteasome subunit beta. (233 aa)
	ccna2	MGC130969 protein; Belongs to the cyclin family. (415 aa)
	psma1	Proteasome subunit alpha type. (261 aa)
	anapc10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	anapc10-2	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	ube2c-2	LOC496302 protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
	Psmb3	Proteasome subunit beta. (205 aa)
	psmb3	Proteasome subunit beta. (205 aa)
	psmd10	LOC495968 protein. (227 aa)
	psmf1	LOC495127 protein. (263 aa)
	psme3	Psme3b protein. (254 aa)
	psme1	LOC494646 protein. (244 aa)
	anapc7	MGC81861 protein. (565 aa)
	psmd7-2	MGC84052 protein. (320 aa)
	psmb7-2	Proteasome subunit beta. (277 aa)
	psma6	Proteasome subunit alpha type. (246 aa)
	anapc7-2	Anapc7-prov protein. (565 aa)
	cdc16	Cdc16-prov protein. (621 aa)
	psmd9	MGC84770 protein. (208 aa)
	psme2	MGC84168 protein. (242 aa)
	rps27a	MGC81889 protein. (156 aa)
	psma5	Proteasome subunit alpha type. (247 aa)
	psmb2	Proteasome subunit beta. (199 aa)
	psmc5-2	MGC80185 protein; Belongs to the AAA ATPase family. (415 aa)
	uba52	MGC80109 protein. (128 aa)
	psme3-2	Psme3 protein. (254 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	psmb7.2	Proteasome subunit beta. (279 aa)
	psma4	Proteasome subunit alpha type. (261 aa)
	psmc3	Psmc3-b protein; Belongs to the AAA ATPase family. (423 aa)
	psmd14	Psmd14-prov protein. (310 aa)
	psmd6	P44s10-prov protein. (389 aa)
	psmd9-2	MGC53232 protein. (213 aa)
	psma3	Proteasome subunit alpha type. (255 aa)
	cdc20-2	Cdc20 protein. (506 aa)
	psmb8	Proteasome subunit beta. (271 aa)
	Q9IA80_XENLA	Securin. (188 aa)
	Nek2	Nek2A. (442 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EZQ1	A0A1L8EZW5	A0A1L8EZQ1	A0A1L8EZW5	Proteasome subunit alpha type.	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	0.996
A0A1L8EZQ1	A0A1L8F3K4	A0A1L8EZQ1	A0A1L8F3K4	Proteasome subunit alpha type.	Proteasome subunit beta.	0.968
A0A1L8EZQ1	A0A1L8F5A2	A0A1L8EZQ1	A0A1L8F5A2	Proteasome subunit alpha type.	VWFA domain-containing protein.	0.988
A0A1L8EZQ1	A0A1L8FDD6	A0A1L8EZQ1	A0A1L8FDD6	Proteasome subunit alpha type.	VWFA domain-containing protein.	0.988
A0A1L8EZQ1	A0A1L8FHS4	A0A1L8EZQ1	A0A1L8FHS4	Proteasome subunit alpha type.	Prot_ATP_ID_OB domain-containing protein.	0.957
A0A1L8EZQ1	A0A1L8FHT5	A0A1L8EZQ1	A0A1L8FHT5	Proteasome subunit alpha type.	AAA domain-containing protein.	0.992
A0A1L8EZQ1	A0A1L8FHT9	A0A1L8EZQ1	A0A1L8FHT9	Proteasome subunit alpha type.	Uncharacterized protein.	0.957
A0A1L8EZQ1	A0A1L8FTA7	A0A1L8EZQ1	A0A1L8FTA7	Proteasome subunit alpha type.	Ubiquitin-like domain-containing protein.	0.883
A0A1L8EZQ1	A0A1L8G3T0	A0A1L8EZQ1	A0A1L8G3T0	Proteasome subunit alpha type.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.994
A0A1L8EZQ1	A0A1L8G5V1	A0A1L8EZQ1	A0A1L8G5V1	Proteasome subunit alpha type.	Ubiquitin-like domain-containing protein.	0.948
A0A1L8EZQ1	A0A1L8GI18	A0A1L8EZQ1	A0A1L8GI18	Proteasome subunit alpha type.	Uncharacterized protein.	0.989
A0A1L8EZQ1	A0A1L8GLZ6	A0A1L8EZQ1	A0A1L8GLZ6	Proteasome subunit alpha type.	Proteasome subunit alpha type.	0.995
A0A1L8EZQ1	A0A1L8GN61	A0A1L8EZQ1	A0A1L8GN61	Proteasome subunit alpha type.	Uncharacterized protein.	0.880
A0A1L8EZQ1	A0A1L8HCZ9	A0A1L8EZQ1	A0A1L8HCZ9	Proteasome subunit alpha type.	Uncharacterized protein.	0.866
A0A1L8EZQ1	A0A1L8HPK4	A0A1L8EZQ1	A0A1L8HPK4	Proteasome subunit alpha type.	Uncharacterized protein.	0.880
A0A1L8EZQ1	A0A1L8HX68	A0A1L8EZQ1	A0A1L8HX68	Proteasome subunit alpha type.	Ubiquitin-like domain-containing protein.	0.883
A0A1L8EZQ1	A0A310TNW1	A0A1L8EZQ1	A0A310TNW1	Proteasome subunit alpha type.	Prot_ATP_ID_OB domain-containing protein.	0.983
A0A1L8EZQ1	Anapc5.L	A0A1L8EZQ1	A0A1L8I1N4	Proteasome subunit alpha type.	Uncharacterized protein.	0.690
A0A1L8EZQ1	Ccna1.L	A0A1L8EZQ1	A0A1L8HIV0	Proteasome subunit alpha type.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.542
A0A1L8EZQ1	Ccna1.S	A0A1L8EZQ1	A0A1L8HAP9	Proteasome subunit alpha type.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.542