195 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8H0Z0	Uncharacterized protein. (388 aa)
	A0A1L8H0Z1	DH domain-containing protein. (259 aa)
	A0A1L8H0Z3	Uncharacterized protein. (223 aa)
	A0A1L8H113	Uncharacterized protein. (295 aa)
	A0A1L8H178	Uncharacterized protein. (72 aa)
	A0A1L8H1R2	Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
	ikbkb	Uncharacterized protein. (769 aa)
	A0A1L8H465	Uncharacterized protein. (1172 aa)
	A0A1L8H547	Uncharacterized protein. (1608 aa)
	Itsn1.S	Uncharacterized protein. (1670 aa)
	ngf	NGF domain-containing protein; Belongs to the NGF-beta family. (242 aa)
	Aatf.S	Uncharacterized protein. (535 aa)
	omg	LRRNT domain-containing protein. (427 aa)
	A0A1L8H8W3	Uncharacterized protein. (1214 aa)
	arhgef7	Uncharacterized protein. (818 aa)
	A0A1L8G9U4	Uncharacterized protein. (1231 aa)
	arhgef10-2	DH domain-containing protein. (1379 aa)
	sos1-2	Uncharacterized protein. (1325 aa)
	Arhgef33.L	DH domain-containing protein. (855 aa)
	A0A1L8G7M0	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (445 aa)
	bcl2l11-2	Uncharacterized protein. (194 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	adam17	Uncharacterized protein. (855 aa)
	arhgef4	Uncharacterized protein. (658 aa)
	ngef	Uncharacterized protein. (691 aa)
	arhgef26	Uncharacterized protein. (868 aa)
	Ect2.S	Uncharacterized protein. (987 aa)
	A0A1L8G3U6	Uncharacterized protein. (1234 aa)
	arhgef10	DH domain-containing protein. (1383 aa)
	psen2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (449 aa)
	sos1	Uncharacterized protein. (1325 aa)
	Arhgef33.S	DH domain-containing protein. (805 aa)
	bcl2l11	Uncharacterized protein. (194 aa)
	ripk2-2	Uncharacterized protein. (545 aa)
	A0A1L8FX87	Uncharacterized protein. (1128 aa)
	Trio.L	Uncharacterized protein. (1879 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (283 aa)
	A0A1L8FUV2	Uncharacterized protein. (387 aa)
	ripk2	Uncharacterized protein. (550 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	Myd88.S	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
	Mag.L	Uncharacterized protein. (625 aa)
	Arhgef10l.L	DH domain-containing protein. (1028 aa)
	Arhgef1.L	DH domain-containing protein. (1104 aa)
	arhgef16-2	Uncharacterized protein. (714 aa)
	A0A1L8FLX2	PH domain-containing protein. (366 aa)
	arhgef12	Uncharacterized protein. (1464 aa)
	Casp2.L	Uncharacterized protein; Belongs to the peptidase C14A family. (423 aa)
	A0A1L8FI35	DH domain-containing protein. (1852 aa)
	A0A1L8FHW0	Uncharacterized protein. (480 aa)
	Arhgef19.L	Uncharacterized protein. (570 aa)
	A0A1L8FHG0	Uncharacterized protein. (581 aa)
	Arhgef1.S	DH domain-containing protein. (1108 aa)
	ect2	Uncharacterized protein. (986 aa)
	arhgef16	Uncharacterized protein. (708 aa)
	Arhgef12.S	Uncharacterized protein. (1489 aa)
	A0A1L8FDU4	Uncharacterized protein; Belongs to the peptidase C14A family. (423 aa)
	A0A1L8FDP4	Uncharacterized protein. (1758 aa)
	A0A1L8FDG1	Uncharacterized protein. (180 aa)
	A0A1L8FDF2	Uncharacterized protein. (111 aa)
	A0A1L8FDA2	Uncharacterized protein. (178 aa)
	A0A1L8FD96	Uncharacterized protein. (263 aa)
	A0A1L8FD49	Uncharacterized protein. (230 aa)
	A0A1L8FD28	Uncharacterized protein. (160 aa)
	A0A1L8FD01	Uncharacterized protein. (338 aa)
	A0A310TPJ0	Uncharacterized protein. (248 aa)
	arhgef40-2	Uncharacterized protein. (1439 aa)
	lingo2-2	Ig-like domain-containing protein. (622 aa)
	A0A1L8HXH7	Uncharacterized protein. (1266 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	Kxd1.L	KxDL domain-containing protein. (195 aa)
	arhgef38-2	Uncharacterized protein. (781 aa)
	Casp3.L	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	A0A1L8HU07	Uncharacterized protein; Belongs to the peptidase C14A family. (266 aa)
	A0A1L8HTZ4	Uncharacterized protein; Belongs to the peptidase C14A family. (273 aa)
	ubc	Uncharacterized protein. (533 aa)
	arhgef40	Uncharacterized protein. (1443 aa)
	lingo2	Ig-like domain-containing protein. (611 aa)
	kxd1	KxDL domain-containing protein. (195 aa)
	Arhgef18.S	Uncharacterized protein. (1204 aa)
	A0A1L8HN44	Uncharacterized protein. (741 aa)
	arhgef38	Uncharacterized protein. (781 aa)
	casp3.2	Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
	A0A1L8HJY5	DH domain-containing protein. (2260 aa)
	A0A1L8HIC2	Uncharacterized protein. (349 aa)
	A0A1L8HI67	Uncharacterized protein. (349 aa)
	arhgef25-2	Uncharacterized protein. (751 aa)
	LOC100496837.L	Uncharacterized protein. (360 aa)
	A0A1L8HI45	Uncharacterized protein. (363 aa)
	A0A1L8HI41	Uncharacterized protein. (330 aa)
	A0A1L8HH24	Uncharacterized protein. (1439 aa)
	arhgef7-2	Uncharacterized protein. (802 aa)
	omg-2	LRRNT domain-containing protein. (427 aa)
	Ngf.L	NGF domain-containing protein; Belongs to the NGF-beta family. (232 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	A0A1L8HCP0	Uncharacterized protein. (1470 aa)
	Itsn1.L	Uncharacterized protein. (1270 aa)
	A0A1L8HB63	DH domain-containing protein. (1077 aa)
	A0A1L8HB41	Uncharacterized protein. (1314 aa)
	A0A1L8HA21	Uncharacterized protein. (331 aa)
	A0A1L8H9Z4	Uncharacterized protein. (263 aa)
	A0A1L8H9W0	Uncharacterized protein. (359 aa)
	arhgef25	Uncharacterized protein. (753 aa)
	arhgef2	Uncharacterized protein. (984 aa)
	A0A1L8FCZ4	Uncharacterized protein. (278 aa)
	ncstn-2	Ncstrn_small domain-containing protein. (713 aa)
	aph1a	Uncharacterized protein. (247 aa)
	arhgef11-2	Uncharacterized protein. (1593 aa)
	Nfkbia.L	ANK_REP_REGION domain-containing protein. (315 aa)
	psen1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
	sos2-2	Uncharacterized protein. (1332 aa)
	A0A1L8F951	Uncharacterized protein. (613 aa)
	A0A1L8F824	Uncharacterized protein. (1116 aa)
	Arhgef6.L	Uncharacterized protein. (777 aa)
	A0A1L8F784	Uncharacterized protein. (1352 aa)
	vav2	Uncharacterized protein. (832 aa)
	A0A1L8F5R7	Uncharacterized protein. (531 aa)
	A0A1L8F580	Uncharacterized protein. (126 aa)
	A0A1L8F513	Uncharacterized protein. (183 aa)
	A0A1L8F507	Uncharacterized protein. (167 aa)
	A0A1L8F500	Uncharacterized protein. (147 aa)
	A0A1L8F4Y8	Uncharacterized protein. (342 aa)
	Arhgef2.S	Uncharacterized protein. (1003 aa)
	A0A1L8F4N0	Uncharacterized protein. (219 aa)
	ncstn	Ncstrn_small domain-containing protein. (713 aa)
	arhgef11	Uncharacterized protein. (1606 aa)
	A0A1L8F443	Uncharacterized protein. (2003 aa)
	A0A1L8F3B4	Uncharacterized protein. (1076 aa)
	Arhgef6.S	Uncharacterized protein. (770 aa)
	A0A1L8F2L6	Uncharacterized protein. (213 aa)
	A0A1L8F2K3	Uncharacterized protein. (438 aa)
	A0A1L8F1X3	Uncharacterized protein. (827 aa)
	fgd1	Uncharacterized protein. (867 aa)
	sos2	Uncharacterized protein. (1335 aa)
	A0A1L8EZY9	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
	Nfkbia.S	ANK_REP_REGION domain-containing protein. (312 aa)
	Arhgef3.1.S	Uncharacterized protein. (526 aa)
	Sestd1.L	CRAL-TRIO domain-containing protein. (696 aa)
	A0A1L8EVB9	Uncharacterized protein. (2852 aa)
	gna13	Uncharacterized protein. (377 aa)
	A0A1L8EU29	Transglut_N domain-containing protein. (228 aa)
	A0A1L8EU00	TGc domain-containing protein. (729 aa)
	Tgm6.L	TGc domain-containing protein. (702 aa)
	A0A1L8ETY1	Uncharacterized protein. (225 aa)
	Tgm3.2.L	TGc domain-containing protein. (706 aa)
	A0A1L8ETW3	TGc domain-containing protein. (617 aa)
	sestd1	CRAL-TRIO domain-containing protein. (696 aa)
	A0A1L8ENM9	Uncharacterized protein. (2737 aa)
	Tgm3.1.S	TGc domain-containing protein. (864 aa)
	A0A1L8EMI0	Transglut_N domain-containing protein. (141 aa)
	A0A1L8EMG3	Uncharacterized protein. (383 aa)
	A0A1L8EMF3	Transglut_C domain-containing protein. (181 aa)
	tgm3.2	TGc domain-containing protein. (693 aa)
	A0A1L8EMD5	TGc domain-containing protein. (144 aa)
	P75ntrb-A	Uncharacterized protein. (389 aa)
	ngef-2	Uncharacterized protein. (691 aa)
	arhgef4-2	Uncharacterized protein. (619 aa)
	arhgef26-2	Uncharacterized protein. (868 aa)
	Traf6.S	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
	vav3	Uncharacterized protein. (843 aa)
	Traf6.L	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
	A0A1L8GJQ1	Uncharacterized protein. (151 aa)
	A0A1L8GKL1	Uncharacterized protein. (495 aa)
	A0A1L8GLX9	Uncharacterized protein. (147 aa)
	vav3-2	Uncharacterized protein. (843 aa)
	Fgd4.S	Uncharacterized protein. (758 aa)
	A0A1L8GQR7	PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (762 aa)
	A0A1L8GRU9	Uncharacterized protein; Belongs to the peptidase C14A family. (225 aa)
	Akap13.S	Uncharacterized protein. (2572 aa)
	lingo1	Ig-like domain-containing protein. (606 aa)
	net1	Uncharacterized protein. (584 aa)
	ccdc71l	Uncharacterized protein. (209 aa)
	Arhgef37.S	Uncharacterized protein. (784 aa)
	Fgd4.L	Uncharacterized protein. (822 aa)
	Arhgef37.L	Uncharacterized protein. (852 aa)
	ccdc71l-2	Uncharacterized protein. (213 aa)
	net1-2	Uncharacterized protein. (583 aa)
	lingo1-2	Ig-like domain-containing protein. (606 aa)
	A0A1L8H0Y4	Uncharacterized protein. (150 aa)
	A0A1L8H0Y6	Uncharacterized protein. (1002 aa)
	ngfr	P75 neurotrophin receptor a-1. (401 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	sqstm1	MGC64432 protein. (454 aa)
	vav2-2	MGC68892 protein. (832 aa)
	uba52	MGC80109 protein. (128 aa)
	rps27a	MGC81889 protein. (156 aa)
	vav1	Vav1-prov protein. (845 aa)
	psenen-2	LOC494701 protein. (101 aa)
	psenen	LOC495936 protein. (101 aa)
	gna13-2	Heterotrimeric guanine nucleotide binding protein subunit alpha-13. (377 aa)
	adam17-2	Disintegrin metalloproteinase. (839 aa)
	itsn1	Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for cdc42, and thereby stimulates actin nucleation mediated by wasl and the arp2/3 complex (By similarity). Involved in endocytosis of activated egfr, and probably also other growth factor receptors (By similarity). (1705 aa)
	A0A310UBN1	Uncharacterized protein. (530 aa)
	A0A310U4Z7	Uncharacterized protein. (588 aa)
	A0A1L8I3A3	DH domain-containing protein. (365 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EMD5	A0A1L8EMG3	A0A1L8EMD5	A0A1L8EMG3	TGc domain-containing protein.	Uncharacterized protein.	0.516
A0A1L8EMD5	A0A1L8EU29	A0A1L8EMD5	A0A1L8EU29	TGc domain-containing protein.	Transglut_N domain-containing protein.	0.521
A0A1L8EMG3	A0A1L8EMD5	A0A1L8EMG3	A0A1L8EMD5	Uncharacterized protein.	TGc domain-containing protein.	0.516
A0A1L8EMG3	A0A1L8EU29	A0A1L8EMG3	A0A1L8EU29	Uncharacterized protein.	Transglut_N domain-containing protein.	0.511
A0A1L8ENM9	Arhgef12.S	A0A1L8ENM9	A0A1L8FFX7	Uncharacterized protein.	Uncharacterized protein.	0.664
A0A1L8ENM9	Itsn1.L	A0A1L8ENM9	A0A1L8HCL0	Uncharacterized protein.	Uncharacterized protein.	0.700
A0A1L8ENM9	arhgef12	A0A1L8ENM9	A0A1L8FLD1	Uncharacterized protein.	Uncharacterized protein.	0.664
A0A1L8ENM9	gna13	A0A1L8ENM9	A0A1L8EV46	Uncharacterized protein.	Uncharacterized protein.	0.417
A0A1L8ENM9	gna13-2	A0A1L8ENM9	Q5HZN4	Uncharacterized protein.	Heterotrimeric guanine nucleotide binding protein subunit alpha-13.	0.417
A0A1L8ENM9	vav1	A0A1L8ENM9	Q6DCX0	Uncharacterized protein.	Vav1-prov protein.	0.480
A0A1L8EU29	A0A1L8EMD5	A0A1L8EU29	A0A1L8EMD5	Transglut_N domain-containing protein.	TGc domain-containing protein.	0.521
A0A1L8EU29	A0A1L8EMG3	A0A1L8EU29	A0A1L8EMG3	Transglut_N domain-containing protein.	Uncharacterized protein.	0.511
A0A1L8EVB9	gna13	A0A1L8EVB9	A0A1L8EV46	Uncharacterized protein.	Uncharacterized protein.	0.417
A0A1L8EVB9	gna13-2	A0A1L8EVB9	Q5HZN4	Uncharacterized protein.	Heterotrimeric guanine nucleotide binding protein subunit alpha-13.	0.417
A0A1L8EZY9	A0A1L8F4N0	A0A1L8EZY9	A0A1L8F4N0	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.935
A0A1L8EZY9	A0A1L8FUV2	A0A1L8EZY9	A0A1L8FUV2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.418
A0A1L8EZY9	A0A1L8G7M0	A0A1L8EZY9	A0A1L8G7M0	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.977
A0A1L8EZY9	Traf6.L	A0A1L8EZY9	A0A1L8GIM0	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.597
A0A1L8EZY9	Traf6.S	A0A1L8EZY9	A0A1L8GE35	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.597
A0A1L8EZY9	adam17	A0A1L8EZY9	A0A1L8G4Z1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.458