19 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ngfr	P75 neurotrophin receptor a-1. (401 aa)
	Ngf.L	NGF domain-containing protein; Belongs to the NGF-beta family. (232 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	ngf	NGF domain-containing protein; Belongs to the NGF-beta family. (242 aa)
	ikbkb	Uncharacterized protein. (769 aa)
	A0A1L8GKL1	Uncharacterized protein. (495 aa)
	Traf6.L	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
	Traf6.S	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	ripk2-2	Uncharacterized protein. (545 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (283 aa)
	ripk2	Uncharacterized protein. (550 aa)
	Myd88.S	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
	A0A1L8F1X3	Uncharacterized protein. (827 aa)
	P75ntrb-A	Uncharacterized protein. (389 aa)
	ubc	Uncharacterized protein. (533 aa)
	rps27a	MGC81889 protein. (156 aa)
	sqstm1	MGC64432 protein. (454 aa)
	ubc-2	Ubc-prov protein. (609 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F1X3	A0A1L8G5V1	A0A1L8F1X3	A0A1L8G5V1	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.568
A0A1L8F1X3	A0A1L8GKL1	A0A1L8F1X3	A0A1L8GKL1	Uncharacterized protein.	Uncharacterized protein.	0.502
A0A1L8F1X3	A0A1L8HCZ9	A0A1L8F1X3	A0A1L8HCZ9	Uncharacterized protein.	Uncharacterized protein.	0.521
A0A1L8F1X3	Myd88.S	A0A1L8F1X3	A0A1L8FQF6	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.998
A0A1L8F1X3	Traf6.L	A0A1L8F1X3	A0A1L8GIM0	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
A0A1L8F1X3	Traf6.S	A0A1L8F1X3	A0A1L8GE35	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
A0A1L8F1X3	ikbkb	A0A1L8F1X3	A0A1L8H261	Uncharacterized protein.	Uncharacterized protein.	0.807
A0A1L8F1X3	myd88	A0A1L8F1X3	A0A1L8FV26	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.998
A0A1L8F1X3	ripk2	A0A1L8F1X3	A0A1L8FTF9	Uncharacterized protein.	Uncharacterized protein.	0.502
A0A1L8F1X3	ripk2-2	A0A1L8F1X3	A0A1L8FZI7	Uncharacterized protein.	Uncharacterized protein.	0.502
A0A1L8F1X3	rps27a	A0A1L8F1X3	Q6GMC1	Uncharacterized protein.	MGC81889 protein.	0.568
A0A1L8F1X3	sqstm1	A0A1L8F1X3	Q6PGS1	Uncharacterized protein.	MGC64432 protein.	0.843
A0A1L8F1X3	ubc	A0A1L8F1X3	A0A1L8HQK4	Uncharacterized protein.	Uncharacterized protein.	0.521
A0A1L8F1X3	ubc-2	A0A1L8F1X3	Q7SY79	Uncharacterized protein.	Ubc-prov protein.	0.521
A0A1L8G5V1	A0A1L8F1X3	A0A1L8G5V1	A0A1L8F1X3	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.568
A0A1L8G5V1	A0A1L8GKL1	A0A1L8G5V1	A0A1L8GKL1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.415
A0A1L8G5V1	A0A1L8HCZ9	A0A1L8G5V1	A0A1L8HCZ9	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.935
A0A1L8G5V1	Myd88.S	A0A1L8G5V1	A0A1L8FQF6	Ubiquitin-like domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.689
A0A1L8G5V1	Traf6.L	A0A1L8G5V1	A0A1L8GIM0	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.951
A0A1L8G5V1	Traf6.S	A0A1L8G5V1	A0A1L8GE35	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.951