31 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8HFU4	Endo/exonuclease/phosphatase domain-containing protein. (385 aa)
	A0A1L8FNH2	Uncharacterized protein. (217 aa)
	A0A1L8G8A5	Uncharacterized protein. (215 aa)
	A0A1L8G8H0	Uncharacterized protein. (334 aa)
	Rwdd2a.L	RWD domain-containing protein. (290 aa)
	A0A1L8GAI1	Uncharacterized protein. (287 aa)
	A0A1L8GAT9	Uncharacterized protein. (288 aa)
	Rwdd3.S	RWD domain-containing protein. (246 aa)
	A0A1L8GKE5	Uncharacterized protein. (333 aa)
	uba2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (641 aa)
	A0A1L8GRL7	Uncharacterized protein. (208 aa)
	A0A1L8GRM5	Uncharacterized protein. (184 aa)
	A0A1L8GSL8	Uncharacterized protein. (181 aa)
	hmgn1	Uncharacterized protein. (105 aa)
	rwdd2b	RWD domain-containing protein. (302 aa)
	A0A1L8FLF2	Uncharacterized protein. (312 aa)
	hmgn1-2	High mobility group HMG-14. (106 aa)
	A0A310U7P8	Uncharacterized protein. (178 aa)
	A0A310U2T5	Uncharacterized protein. (372 aa)
	A0A1L8HVS9	Uncharacterized protein. (230 aa)
	A0A1L8HVR7	Uncharacterized protein. (216 aa)
	A0A1L8HMQ9	Uncharacterized protein. (200 aa)
	sae1	ThiF domain-containing protein. (344 aa)
	A0A1L8F2I5	Uncharacterized protein. (323 aa)
	A0A1L8HEP2	Uncharacterized protein. (243 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	A0A1L8ETK0	Uncharacterized protein. (280 aa)
	A0A1L8EUG6	Uncharacterized protein. (156 aa)
	A0A1L8EVJ0	Uncharacterized protein. (262 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	A0A1L8F238	Uncharacterized protein. (228 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GAT9	A0A1L8HVR7	A0A1L8GAT9	A0A1L8HVR7	Uncharacterized protein.	Uncharacterized protein.	0.497
A0A1L8GAT9	A0A310U7P8	A0A1L8GAT9	A0A310U7P8	Uncharacterized protein.	Uncharacterized protein.	0.493
A0A1L8HFU4	A0A1L8HVR7	A0A1L8HFU4	A0A1L8HVR7	Endo/exonuclease/phosphatase domain-containing protein.	Uncharacterized protein.	0.478
A0A1L8HFU4	A0A310U7P8	A0A1L8HFU4	A0A310U7P8	Endo/exonuclease/phosphatase domain-containing protein.	Uncharacterized protein.	0.470
A0A1L8HVR7	A0A1L8GAT9	A0A1L8HVR7	A0A1L8GAT9	Uncharacterized protein.	Uncharacterized protein.	0.497
A0A1L8HVR7	A0A1L8HFU4	A0A1L8HVR7	A0A1L8HFU4	Uncharacterized protein.	Endo/exonuclease/phosphatase domain-containing protein.	0.478
A0A1L8HVR7	A0A310U7P8	A0A1L8HVR7	A0A310U7P8	Uncharacterized protein.	Uncharacterized protein.	0.476
A0A310U7P8	A0A1L8GAT9	A0A310U7P8	A0A1L8GAT9	Uncharacterized protein.	Uncharacterized protein.	0.493
A0A310U7P8	A0A1L8HFU4	A0A310U7P8	A0A1L8HFU4	Uncharacterized protein.	Endo/exonuclease/phosphatase domain-containing protein.	0.470
A0A310U7P8	A0A1L8HVR7	A0A310U7P8	A0A1L8HVR7	Uncharacterized protein.	Uncharacterized protein.	0.476
Rwdd2a.L	Sumo1.L	A0A1L8G9I7	A0A1L8EWZ5	RWD domain-containing protein.	Ubiquitin-like domain-containing protein.	0.470
Rwdd2a.L	Sumo1.S	A0A1L8G9I7	A0A1L8EPQ0	RWD domain-containing protein.	Ubiquitin-like domain-containing protein.	0.470
Rwdd2a.L	sae1	A0A1L8G9I7	A0A1L8F8T2	RWD domain-containing protein.	ThiF domain-containing protein.	0.603
Rwdd2a.L	uba2	A0A1L8G9I7	A0A1L8GLB0	RWD domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.401
Sumo1.L	Rwdd2a.L	A0A1L8EWZ5	A0A1L8G9I7	Ubiquitin-like domain-containing protein.	RWD domain-containing protein.	0.470
Sumo1.L	rwdd2b	A0A1L8EWZ5	A0A1L8HCR4	Ubiquitin-like domain-containing protein.	RWD domain-containing protein.	0.402
Sumo1.L	sae1	A0A1L8EWZ5	A0A1L8F8T2	Ubiquitin-like domain-containing protein.	ThiF domain-containing protein.	0.997
Sumo1.L	uba2	A0A1L8EWZ5	A0A1L8GLB0	Ubiquitin-like domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.998
Sumo1.S	Rwdd2a.L	A0A1L8EPQ0	A0A1L8G9I7	Ubiquitin-like domain-containing protein.	RWD domain-containing protein.	0.470
Sumo1.S	rwdd2b	A0A1L8EPQ0	A0A1L8HCR4	Ubiquitin-like domain-containing protein.	RWD domain-containing protein.	0.402